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Study: Nurses may have poorest perceptions of workplace safety climate

JCompared to other groups of healthcare practitioners, nurses may have the poorest perceptions of workplace safety climate and the highest rates of injuries and sick time, suggests a single-hospital study in the May/June issue of the Journal of Healthcare Management.

5 Jun 2020

Antiviral effects for COVID-19: Early is better

A new study by an international team of researchers and published on the preprint server medRxiv* in June 2020 describes the possible reasons for inconsistent or null findings in clinical studies of antiviral drugs to date. It proposes a new approach to decide the sample size in light of its findings.

5 Jun 2020

New leukemia immune profiles predict drug resistance, positive responses to immunotherapy

By analyzing 442 samples from three groups of children and adults with acute myeloid leukemia (AML), researchers have identified new immune classes of the disease that predict the likelihood of drug resistance and positive responses to immunotherapy.

5 Jun 2020

Precautions for intimacy, sex, during COVID-19

Amid the coronavirus disease (COVID-19) pandemic, safe sex practices are as important as other measures to prevent infection. Little focus has been given to sexual health, but a new study highlights how couples can reduce the transmission of the novel coronavirus.

5 Jun 2020

A learning health system for dentists

The largest study to date of electronic dental records delves into both previously inaccessible data and data from understudied populations with the ultimate goal of improving oral treatment outcomes.

5 Jun 2020

Study may pave for new therapeutic approaches for Parkinson's disease

Researchers have uncovered a link between the structure of the protein alpha-synuclein and its likelihood to misfold and aggregate.

5 Jun 2020

Study highlights increased consumption of opioids in patients with osteoarthritis

Fentanyl, tramadol or tilidine: New European figures show that even in Europe increasingly more people are taking opioids for pain connected with rheumatic and musculoskeletal diseases.

5 Jun 2020

Experts debate over future Parkinson’s disease trial involving growth factors

Growth factors such as glial cell line-derived neurotrophic factor (GDNF) were initially thought to be exciting new treatments for Parkinson's disease (PD), but trials have been disappointing.

5 Jun 2020

WHO resumes hydroxychloroquine drug trial in COVID-19

The coronavirus disease (COVID-19) has rippled across the world with a devastating effect. As scientists raced to find an effective treatment for patients, existing malaria and rheumatoid arthritis drug hydroxychloroquine became one of the most popular candidates.

5 Jun 2020

New analysis supports first-line stereotactic radiosurgery for small cell lung cancer

The international First-line Radiosurgery for Small-Cell Lung Cancer (FIRE-SCLC) analysis led by University of Colorado Cancer Center researchers and published today in JAMA Oncology details clinical outcomes for 710 patients with brain metastases from small cell lung cancer treated with first-line stereotactic radiosurgery (SRS), without prior treatment with whole-brain radiation (WBRT) or prophylactic cranial irradiation (PCI).

5 Jun 2020

New report documents trends before the legalization of cannabis in Michigan

Nearly twelve years ago, Michigan voters approved the use of medical cannabis by residents with certain health conditions. A year and a half ago, they voted to approve its use by all adults, for any reason.

5 Jun 2020

Trial results show efficacy of netakimab for treating moderate-to-severe plaque psoriasis

Netakimab is a humanized anti-interleukin 17A antibody approved for the treatment of moderate-to-severe plaque psoriasis.

5 Jun 2020

U.K. doctors test lipid ibuprofen as COVID-19 treatment

The non-steroidal anti-inflammatory drug (NSAID) Ibuprofen is being tested as a potential treatment for the coronavirus disease (COVID-19). Doctors in the United Kingdom rolled out a clinical trial of the everyday painkiller to see if it reduces respiratory failure in patients experiencing severe COVID-19 disease.

4 Jun 2020

Assessing the integrity of remdesivir clinical trial during COVID-19 pandemic

As acknowledged in the first remdesivir double-blind placebo-controlled clinical trial addressing treatment for COVID-19 recently published in Lancet (Wang, et al., April 29, 2020), a statistician at Rutgers Cancer Institute of New Jersey was called on to guard the integrity of that trial.

4 Jun 2020

Current advances in nanoparticles and their role as anticancer drug-delivery vectors

Nanotechnology has contributed a great deal to the field of medical science. It has enabled researchers to design tools to deliver drugs to specific targets in a living organism.

4 Jun 2020

A SARS-CoV-2 antibody magnetic immuno-detection test

A new report, released on the preprint server bioRxiv by researchers at the Fraunhofer Institute for Molecular Biology and Applied Ecology, describes the development of an innovative serologic test that could provide a fast, easy, and inexpensive method of detecting high titers of antibody in the serum of SARS-CoV-2 infected people.

4 Jun 2020

Designing a prototype spike protein vaccine for SARS-CoV-2

A recent study published on the preprint server bioRxiv in June 2020 reports the development of a prototype vaccine containing multiple antigenic sites, based on the spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is causing the current COVID-19 pandemic. If successful, this could lead to the development of an effective, non-allergenic vaccine that induces both humoral and cellular immunity.

4 Jun 2020

Comparing genomes to understand how mutations affect the COVID-19 pandemic

Now, a new study by researchers at the Massachusetts Institute of Technology and the Center for Computational Biology, Flatiron Institute and published online on the bioRxiv preprint server describes how the use of comparative genomics helps to identify protein-coding and non-coding functional genes.

4 Jun 2020

SARS-CoV-2 gene deletions may cause milder infections and increase human-to-human transmission

In their recent paper released on the bioRxiv preprint server, a research group from Spain demonstrated how genome changes and deletions in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could represent a strategy of natural selection used for lessening the impact of infection in order to increase viral transmission potential.

4 Jun 2020

Malaria risk in deforestation hotspots linked to demand for agricultural commodities

A paper recently published in Nature Communications is the first to show a connection between demand from certain developed countries for agricultural commodities and the growing risk of malaria in the countries that supply those goods.

4 Jun 2020