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Cascade Chemistry selected to help speed clinical testing of promising investigational drug for COVID-19

Cascade Chemistry, a leading contract research and manufacturing organization serving the pharmaceutical, materials, and chemical industries, today announced that it has been selected to produce the active pharmaceutical ingredient for clinical trial supplies of RBT-9, an investigational therapy entering a Phase 2 trial for the treatment of COVID-19 patients who are at high risk of deteriorating health due to age or comorbid conditions such as kidney or cardiovascular disease.

16 Jun 2020

Why improved pneumonia diagnosis is needed now more than ever

News-Medical speaks to Dr. William La Via about why improved pneumonia diagnosis is vital, especially in the wake of the COVID-19 pandemic.

16 Jun 2020

Cell signaling pathway could treat chronic kidney disease and other medical conditions

Scientists have discovered an important cell signaling pathway in the kidney which if stopped, could hold the key to treating chronic kidney disease as well as other deadly conditions, including heart attack and stroke.

16 Jun 2020

Study highlights processes that act as barriers to use evidence-based pulmonary embolism testing

Common barriers exist to the use of risk stratification tools in the evaluation of pulmonary embolism in the emergency department and provide insight into where to focus efforts for future implementation endeavors.

16 Jun 2020

COVID-19 health crisis highlights food insecurity among children

One in four households with children have reported a child experiencing hunger as a result of the COVID-19 health crisis, according to the latest CUNY SPH COVID-19 tracking survey.

16 Jun 2020

Study shows high folate levels associated with improved cognition in older adults

A new study led by researchers from The Irish Longitudinal Study on Ageing (TILDA) at Trinity College Dublin challenges claims from some international scientific circles, that having high blood levels of folate (folic acid) increases the risk of poor cognition in older adults, especially in those with low levels of vitamin B12.

16 Jun 2020

New mapping tool details SNAP policies related to food shopping during the pandemic

The complex food shopping patterns that financially insecure families employ have been upended by the COVID-19 crisis.

16 Jun 2020

Link between ALS and Alzheimer's disease can help advance the search for new therapies

On the surface, amyotrophic lateral sclerosis (ALS) and Alzheimer's disease share two commonalities: Both are progressively debilitating neurodegenerative conditions--meaning symptoms get worse--and, at least for now, neither has an effective treatment, let alone a cure.

16 Jun 2020

Many Americans face high out-of-pocket medical costs for COVID-19 hospitalizations

If past hospitalizations for pneumonia and other respiratory illnesses are any guide, many Americans could face high out-of-pocket medical costs for COVID-19 hospitalizations despite the fact that many insurers have waived their cost-sharing requirements, a study from researchers at Johns Hopkins Bloomberg School of Public Health suggests.

16 Jun 2020

Researchers call for policy reform in nursing support amid current pandemic

There are close to 28 million nurses around the world who comprise a global workforce that delivers about 90 percent of primary healthcare, including frontline response to the COVID-19 pandemic.

16 Jun 2020

Blood vessels can sense the metabolic state of neighboring neural cells, shows study

The brain is our most energy-hungry and metabolically active organ. It is responsible for our thoughts, ideas, movement and ability to learn.

16 Jun 2020

Scientists develop self-assessment tool for evaluation and treatment of COVID-19

Of the more than 275,000 people worldwide who accessed a USC web-based COVID-19 patient self-assessment tool, only 20 percent reported severe symptoms requiring immediate medical attention, according to new research published in the Journal of General Internal Medicine.

16 Jun 2020

Scientists develop molecules that can remodel gut bacteria to a healthier state

Scientists at Scripps Research have developed molecules that can remodel the bacterial population of intestines to a healthier state and they have shown--through experiments in mice--that this reduces cholesterol levels and strongly inhibits the thickened-artery condition known as atherosclerosis.

16 Jun 2020

Early genetic rescue may be a potential therapy in autism spectrum disorder

A mouse study by Craig Powell, M.D., Ph.D., and colleagues suggests that early genetic rescue may be a potential therapy in autism spectrum disorder or ASD.

16 Jun 2020

Micro-dystrophin gene therapy can improve outcomes in children with Duchenne muscular dystrophy

Researchers from Nationwide Children's Hospital have published in JAMA Neurology results from the first four patients treated in the first clinical trial of systemic delivery of micro-dystrophin gene therapy in children with Duchenne muscular dystrophy (DMD) - and initial findings suggest that the therapy can provide functional improvement that is greater than that observed under the standard of care.

16 Jun 2020

Study reports structure of enzyme activator for high pathogenic avian influenza

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing the current pandemic of COVID-19, is the focus of many investigators seeking to find an effective vaccine or therapeutic. Among the potential targets are various protease enzymes suspected of allowing the virus to gain entry to host cells and establish a successful infection.

16 Jun 2020

People who feel social disconnection appear to have a lonelier, neural self-representation

Social connection with others is critical to a person's mental and physical well-being. How the brain maps relationships with other people in relation to one's self has long been a mystery.

16 Jun 2020

SARS-CoV-2 mutation reduces S1 shedding, increases infective potential

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the seventh coronavirus known to infect humans. SARS-CoV-2 emerged in the last month of 2019 in Wuhan, China, sparking off the ongoing COVID-19 pandemic. This virus enters the host cells through receptor binding and membrane fusion between the viral and host cell membrane.

16 Jun 2020

Oxytocin study may help treat a variety of psychiatric conditions

During the pandemic lockdown, as couples have been forced to spend days and weeks in one another's company, some have found their love renewed while others are on their way to divorce court.

16 Jun 2020

Antibody cocktail is being tested in human COVID-19 trials

Following two studies that screened thousands of human antibodies to SARS-CoV-2 to identify highly potent pairs, in which both antibodies bind the viral target simultaneously, a resultant antibody cocktail is being tested in human trials.

16 Jun 2020

Medical News

Cascade Chemistry selected to help speed clinical testing of promising investigational drug for COVID-19

Why improved pneumonia diagnosis is needed now more than ever

Cell signaling pathway could treat chronic kidney disease and other medical conditions

Study highlights processes that act as barriers to use evidence-based pulmonary embolism testing

COVID-19 health crisis highlights food insecurity among children

Study shows high folate levels associated with improved cognition in older adults

New mapping tool details SNAP policies related to food shopping during the pandemic

Link between ALS and Alzheimer's disease can help advance the search for new therapies

Many Americans face high out-of-pocket medical costs for COVID-19 hospitalizations

Researchers call for policy reform in nursing support amid current pandemic

Blood vessels can sense the metabolic state of neighboring neural cells, shows study

Scientists develop self-assessment tool for evaluation and treatment of COVID-19

Scientists develop molecules that can remodel gut bacteria to a healthier state

Early genetic rescue may be a potential therapy in autism spectrum disorder

Micro-dystrophin gene therapy can improve outcomes in children with Duchenne muscular dystrophy

Study reports structure of enzyme activator for high pathogenic avian influenza

People who feel social disconnection appear to have a lonelier, neural self-representation

SARS-CoV-2 mutation reduces S1 shedding, increases infective potential

Oxytocin study may help treat a variety of psychiatric conditions

Antibody cocktail is being tested in human COVID-19 trials

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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