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Researchers visualize molecular organization of TNFα receptor molecules

Whether a sick cell dies, divides, or travels through the body is regulated by a sophisticat-ed interplay of signal molecules and receptors on the cell membrane.

17 Jan 2020

Amblyopia treatment may need to be revised, research suggests

When University of California, Irvine neurobiologist Carey Y.L. Huh, Ph.D., set her sights on discovering more about amblyopia, she brought personal insight to her quest. As a child, Huh was diagnosed with the condition, which is often called "lazy eye."

17 Jan 2020

Research: Firms’ strategic decisions affect evolution of activism and emergence of mobilization

According to received wisdom, local activism against the establishment of industrial plants follows a cycle, with its highest intensity a short time after mobilization.

17 Jan 2020

Inexpensive drug may be used to counteract treatment resistance in patients with leukemia

A common and inexpensive drug may be used to counteract treatment resistance in patients with acute myeloid leukemia, one of the most common forms of blood cancer.

17 Jan 2020

Finding has major ramifications for ongoing drug development against MLL-rearranged leukemia

A massive research effort over more than a quarter century has tried to make personalized blood stem cells for use in treating leukemias, among many other uses.

17 Jan 2020

Fitness tracker devices show potential as predictors of flu outbreaks

Researchers at Scripps Research Translational Institute have found that fitness tracker devices – wearable tracker devices that measure heart rate and sleep duration – are better predictors of real-time flu outbreaks than current surveillance methods.

17 Jan 2020

Discovery on heart cell research may lead to inaccurate data

Researchers studying proteins in heart cells have unexpectedly discovered that a common microscopy fluorescent protein carries reversible photobleaching properties. This phenomenon may lead to inaccurate or unreliable data.

17 Jan 2020

Scientists urge further caution on use of Viagra for fetal therapy

University of Manchester scientists investigating a possible treatment for fetal growth restriction, a condition in which babies grow poorly in the womb, have urged further caution on the use of Viagra.

17 Jan 2020

First randomized clinical trial compares targeted therapies for acute lymphoblastic leukemia

Researchers from St. Jude Children's Research Hospital and the Chinese Children's Cancer Group led the first randomized, Phase III clinical trial comparing targeted therapies for acute lymphoblastic leukemia (ALL) driven by the Philadelphia chromosome.

17 Jan 2020

Improved microfluidic brain chip can assess the effectiveness of cancer drugs in record time

The Akay Lab biomedical research team at the University of Houston is reporting an improvement on a microfluidic brain cancer chip previously developed in their lab.

17 Jan 2020

Estrogen plays a role in expansion of liver metastases in non-sex-specific cancers

It is known that the tumor microenvironment plays an important role in the progression of cancer. But could estrogen present in this microenvironment facilitate the growth of liver metastases in women affected by colon, pancreatic and lung cancers?

17 Jan 2020

UT Southwestern study identifies new vulnerability in kidney tumors

A UT Southwestern researcher led a team that identified a new vulnerability in kidney tumors, the 10th most common cause of cancer death in men and women.

17 Jan 2020

Employers’ dream of controlling health costs turns to workers’ sleep

Charlie Blakey had a sense he was sleeping poorly since he often would wake up tired and hear from his wife how loudly he breathed during the night.

17 Jan 2020

Most youths do not get timely addiction treatment after opioid overdose

A study of more than 4 million Medicaid claims records during a recent seven-year period concludes that less than a third of the nearly 3,800 U.S. adolescents and young adults who experienced a nonfatal opioid overdose got timely (within 30 days) follow-up addiction treatment to curb or prevent future misuse and reduce the risk of a second overdose.

17 Jan 2020

15 percent of people in the US are physically inactive, CDC report says

The new year may have motivated people to jot down their fitness goals, but a new country-wide map of inactivity in the Centers for Disease Control and Prevention (CDC), may show that this might not be feasible unless people start to become more physically active.

17 Jan 2020

New HIV infections among gay and bisexual men in the UK fall by 71 percent

The Human Immunodeficiency Virus (HIV) is a highly contagious infection usually transmitted through body fluids during sexual contact, blood transfusion, during pregnancy, delivery, and breastfeeding through breast milk. Worldwide, there were about 37.9 million people across the globe with HIV in 2018, and approximately 1.7 million people became newly infected across the globe in 2018 alone.

16 Jan 2020

Discovery of mechanism by which Zika virus enters brain cells

Two independent studies published by Cell Press on January 16, 2020, report that the mechanism by which Zika virus enters brain cells has been identified and even more, exploited to prevent Zika infection and to kill cancer cells instead.

16 Jan 2020

Genetically engineered mosquitoes halt Dengue spread

A new study published in the journal PLOS Pathogens in January 2020 reports the development of mosquitoes that have been genetically modified to resist infection by several types of the dengue virus. This is the first time ever that all types of the virus have been targeted by the engineering of the mosquito DNA. Covering all virus types is essential to achieve proper disease control.

16 Jan 2020

Sepsis killing more people than earlier thought

According to a new study published in the latest issue of The Lancet, this week, more people across the globe are dying of sepsis than earlier believed. A team from the University of Pittsburgh and University of Washington schools of medicine led the research along with their colleagues from different disciplines.

16 Jan 2020

"Jumping genes" within eggs determine their survival

Females are born with a finite supply of eggs and with age the genetic quality of the eggs decline say researchers from Carnegie Institute. The study from researchers Marla Tharp, Safia Malki, and Alex Bortvin was published in the latest issue of Nature Communications. The study was titled, “Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity.”

16 Jan 2020