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Targeting PI3Kβ alone and with combination therapy in PTEN-deficient tumors

The cover for issue 11 of Oncotarget features Figure 6, "Effects of AZD8186 in combination with anti-PD1 on syngeneic models," by Owusu-Brackett, et al.

18 Mar 2020

Viewpoint: Could infectious pathogens play a role in Alzheimer's disease?

For researchers investigating Alzheimer's Disease (AD), a devastating neurodegenerative illness afflicting close to 6 million Americans, it is the best and worst of times.

18 Mar 2020

Key COVID-19 information for gastroenterologists and patients with digestive conditions

A paper published today in Clinical Gastroenterology and Hepatology by clinicians at Icahn School of Medicine at Mount Sinai outlines key information gastroenterologists and patients with chronic digestive conditions need to know about COVID-19, or coronavirus.

18 Mar 2020

Obese children more prone to anxiety, depression and shortening of life

Two studies published in the journals PLOS Medicine and BMC Medicine in March 2020 show that obesity in childhood is linked to a higher risk of future anxiety, depression, and death in early adult life compared to children in the general population. This could shape efforts to detect specific risk factors that predispose children to obesity and thus prevent it.

18 Mar 2020

A view from the front lines of California’s COVID-19 battle

On Tuesday, Dr. Jeanne Noble devoted time between patient visits to hanging clear 2-gallon plastic bags at each of her colleagues' workstations.

18 Mar 2020

Drug from scorpion venom could offer hope for children with fetal alcohol spectrum disorder

A research team led by Children's National Hospital faculty was able to "rescue" a pre-clinical model of fetal alcohol spectrum disorder in juvenile models, reversing motor skill deficits with the help of a novel drug derived from scorpion venom.

18 Mar 2020

Psychosis may be caused by problems with specialized nerve cells

A new Japanese study in mice published in the journal Nature indicates that the cause of the profound mental disturbance termed psychosis could be due to defects in the functioning of specialized nerve cells deep inside the brain, and due to some types of learning behavior. This could help understand how delusions arise in psychosis or schizophrenia, and eventually to develop therapies for these conditions.

18 Mar 2020

$FLS care effective for patients with fragility fractures$

FLS care effective for patients with fragility fractures

For patients with fragility fractures related to underlying bone weakness, a dedicated fracture liaison service can lower the risk of subsequent fractures, suggests a study in the March 18, 2020 issue of The Journal of Bone & Joint Surgery.

18 Mar 2020

Researchers identify new way to treat Danon disease using gene therapy

Danon disease is a very rare, life-threatening condition where the fundamental biological process of removing and recycling proteins does not work.

18 Mar 2020

Patient navigators reduce ER visits, hospitalization for high consumers of health care

Texas is one of a handful of states operating under a Medicaid 1115 Transformation Waiver that allows the expansion of Medicaid managed care while simultaneously maintaining hospital funding.

18 Mar 2020

Why is the tobacco industry supporting wider access to medical cannabis?

A new study published in the BMJ reveals disturbing connections between organizations and groups that are lobbying for broader access to medical cannabis and those who are fighting for the legalization of recreational cannabis. This raises questions as to the reasons behind the industry’s support for measures that will make it easier for patients to gain access to medical cannabis – is it because of the knowledge that by so doing, they will also be able to market the drug for recreational use in the UK?

18 Mar 2020

Pregnancy rate more than doubled with online program for infertile women

A new study published in March 2020 in the journal PLOS ONE reports that the online version of a well-respected program that counsels infertile women achieved the same level of success as the person-to-person equivalent. This was true about both the reduction in emotional distress and the increase in pregnancy rates.

18 Mar 2020

Social media giants join forces to tackle spread of fake coronavirus news

Social media giants such as Facebook, Google, LinkedIn, Microsoft, Reddit, Twitter, and YoutTube have, for the first time, joined hands to fight the spread of fake news on their platforms. They have issued a joint statement.

18 Mar 2020

How to disinfect your home when someone has COVID-19

The novel coronavirus has continued to infect hundreds of thousands of individuals. The associated disease COVID-19 was declared a pandemic by the World Health Organization last week.

18 Mar 2020

UK puts emergency laws in place for coronavirus

The United Kingdom has announced emergency laws to curb the spread of the coronavirus disease (COVID-19), giving the government more powers to protect public health, strengthen social care, support the public, and boost the NHS capacity.

18 Mar 2020

Individuals should to 'drink to thirst' to manage exercise-related hyponatremia

Hyponatremia is a condition of low sodium concentration in the blood. Prolonged overhydration during exercise is the primary cause of all forms of exercise-associated hyponatremia (EAH) and should be avoided.

18 Mar 2020

C-Path and Lundbeck join hands to improve scientific community's insight in Alzheimer's

The Critical Path Institute and H. Lundbeck A/S are proud to announce that they will work together to significantly improve the scientific community's insight in Alzheimer's disease through Lundbeck's contribution of a unique set of clinical trial data from more than 2,500 AD patients to the Critical Path for Alzheimer's Disease consortium's integrated database for qualified researchers across the globe to access.

18 Mar 2020