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Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate payloads, today announced data demonstrating the potent efficacy and favorable toxicity profile of a reduced potency analogue from its Pyridinobenzodiazepine ADC payload platform in solid tumor models.

From Pheon Therapeutics 29 Oct 2019

Employers are scaling back their dependence on high-deductible health plans

Everything old is new again. As open enrollment gets underway for next year's job-based health insurance coverage, some employees are seeing traditional plans offered alongside or instead of the plans with sky-high deductibles that may have been their only choice in the past.

29 Oct 2019

UVA scientists awarded $2.7 million NIH grant to study genetic variation linked with heart disease

The National Institutes of Health has awarded a $2.7 million grant to scientists from the University of Virginia to study a genetic variation associated with coronary heart disease.

29 Oct 2019

States try a gentler approach to getting Medicaid enrollees to work

Under pressure from the Republican-controlled Pennsylvania legislature to require Medicaid recipients to work as a condition for coverage, state health officials have devised a gentler approach to getting beneficiaries into jobs.

29 Oct 2019

NYU researcher awarded $1.7 million NIH grant to optimize cancer treatment

Weiqiang Chen, assistant professor of biomedical engineering and mechanical and aerospace engineering at the NYU Tandon School of Engineering, has been awarded the Maximizing Investigators' Research Award (R35) from the National Institute of General Medical Sciences, a division of the National Institutes of Health.

29 Oct 2019

NEOMED professor receives DOD grant to explore if exercise proves to be neuroprotective

Sheila Fleming, Ph.D., an assistant professor of pharmaceutical sciences at Northeast Ohio Medical University, was recently awarded a three-year, $954,566 grant by the U.S. Army Medical Research Acquisition Activity for the project titled, "Exercise Effects on Synuclein Aggregation, Neuroinflammation, and Neurodegeneration."

29 Oct 2019

Pro-inflammatory protein could play key role in protecting against herpes virus

Researchers at the University of Arizona College of Medicine - Phoenix have discovered a function in a pro-inflammatory protein that could play an important part in improving current and future therapeutics for the herpes virus.

29 Oct 2019

Snooze you can use: California legislates more sleep for better health

Teenagers don’t get enough sleep, and California's effort to fix the problem may serve as a wake-up call to other states' lawmakers.

29 Oct 2019

Fresenius Medical Care enhances support for home dialysis patients in Western Australia

Fresenius Medical Care, the world's leading provider of dialysis products and services, announced the further enhancement of support for home dialysis patients in Western Australia.

29 Oct 2019

Farmworkers face daunting health risks in California’s wildfires

Farm laborers in yellow safety vests walked through neatly arranged rows of grapes Friday, harvesting the last of the deep purple bundles that hung from the vines, even as the sky behind them was dark with soot.

29 Oct 2019

Novel antibodies could provide a universal flu vaccine

Now, a new study published in the journal Science on October 25, 2019, reports on a set of three novel antibodies that bind to another type of viral cell surface antigen called neuraminidase (NA) that is necessary for viral replication.

28 Oct 2019

Horrifying HIV epidemic in Pakistani town children due to syringe reuse

Allegations abound in this small Pakistani town of Ratodero, in the province of Sindh. Stung by poverty, pediatricians, barbers and dentists alike brave the risk of transmitting fatal and incurable HIV infection by sharing the same needles, tools and blades for multiple patients and clients, without sterilizing them in between uses.

28 Oct 2019

Counting helps infants relate things to numbers

Infants and animals are able to understand approximate quantities of different types, in terms of relative proportions of the numbers of different sets of objects, provided the difference in numbers is large. This is represented by approximate number systems (ANS) in a rough way.

28 Oct 2019

Discovery of causal link between hydrogen sulfide and schizophrenia

Researchers from the RIKEN Center for Brain Science in Japan have found certain chemical markers that are associated with schizophrenia. They worked with lab mice with models of schizophrenia as well as post mortem brain specimens of persons with schizophrenia. The study titled, “Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology,” was published in the latest issue of the journal EMBO Molecular Medicine.

28 Oct 2019

WHO expert panel discusses digital technology in public health

For the first time ever, the World Health Organization (WHO) has brought together experts in the domain of public health to discuss how digital health technologies can help achieve its goals of global health. The panel, called the Digital Health Technical Advisory Group, discussed a wide range of topics from how data is dealt with, through issues of cost-effectiveness and evidence-based decision making, to making digital health a widely available and ethically bound solution.

28 Oct 2019

Sugar-sweetened acidic drinks linked to obesity and tooth wear among adults

A new study published today in the journal Clinical Oral Investigations, has found that sugar-sweetened acidic drinks, such as soft drinks, is the common factor between obesity and tooth wear among adults.

28 Oct 2019

Work in progress on medicine for treatment of ulcerative colitis

IKBFU center for clinical research scientists have participated in the international VARSITY clinical research. It's the world's first research aimed at finding the most effective drug among anti-inflammatory ones for the treatment of ulcerative colitis.

28 Oct 2019

Some types of proteins can stabilize damaged DNA

At the University of Copenhagen, researchers have discovered how some types of proteins stabilize damaged DNA and thereby preserve DNA function and integrity. This new finding also explains why people with inborn or acquired defects in certain proteins cannot keep their DNA stable and develop diseases such as cancer.

28 Oct 2019

Eating one avocado a day associated with lower levels of LDL

Move over, apples -- new research from Penn State suggests that eating one avocado a day may help keep "bad cholesterol" at bay.

28 Oct 2019

New diagnostic technique enables grading of tumor consistency using MRI

Researchers from Charité - Universitätsmedizin Berlin have developed a new diagnostic technique which enables the grading of tumor consistency using magnetic resonance imaging (MRI). The researchers used an imaging technique known as tomoelastography to visualize the mechanical properties of liver tumors.

28 Oct 2019