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St George Street Capital signs agreement with AstraZeneca to develop two compounds in the clinic

St George Street Capital, a UK registered charity, has signed a license agreement with AstraZeneca to develop two compounds in the clinic: one for idiopathic male infertility, and the other for renal transplant rejection. The agreement enables additional compounds to be added in the future.

From AstraZeneca 14 Oct 2019

New data shows rise in obesity prevalence among reception-aged children in 2018-19

Obesity prevalence among reception-aged schoolchildren in England increased between 2017-18 and 2018-19, new statistics from NHS Digital show.

14 Oct 2019

Mogrify raises additional $16 million to accelerate the development of life-saving cell therapies

Mogrify Ltd (Mogrify), a UK company aiming to transform the development of life-saving cell therapies, today announced the initial close of its Series A funding. The Company raised $16 million USD in this round, bringing the total investment to over $20 million USD to date.

14 Oct 2019

Femtogenix announces efficacy, toxicity data of new DNA-binding ADC payload molecules

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate (ADC) payloads, today announced data verifying the favorable toxicity profile and potent efficacy of its Pyridinobenzodiazepine (PDD) ADC payload platform in tumor cell models.

14 Oct 2019

Poor paternal diet may impact the heart health of offspring

When trying to get pregnant, couples often change their lifestyles, going on crash diets or taking up stricter exercise regimens. New research, done on mice, suggests that men might be best off avoiding crash diets, as it may affect the heart health of their offspring.

14 Oct 2019

California’s new transparency law reveals steep rise in wholesale drug prices

Drugmakers fought hard against California's groundbreaking drug price transparency law, passed in 2017. Now, state health officials have released their first report on the price hikes those drug companies sought to shield.

14 Oct 2019

Patients eligible for charity care instead get big bills

When Ashley Pintos went to the emergency room of St. Joseph Medical Center in Tacoma, Wash., in 2016, with a sharp pain in her abdomen and no insurance, a representative demanded a $500 deposit before treating her.

14 Oct 2019

Researchers uncover rising trends of suicide attempts among black teens

Adding to what is known about the growing crisis of suicide among American teens, a team led by researchers at the McSilver Institute for Poverty Policy and Research at New York University have uncovered several troubling trends during the period of 1991-2017, among Black high school students in particular.

14 Oct 2019

New study could change the way traumatic brain injuries are treated

Traumatic brain injuries, including concussions, can be caused by anything from sports injuries to battlefield trauma.

14 Oct 2019

Overdose prevention should also focus on alcohol use, study suggests

For several years, the national spotlight has shone on the need to prevent and rapidly treat opioid overdoses. But a new study suggests a need for more focus on the risk of alcohol overdoses among people who use opioids of all kinds, as well as cocaine, marijuana and certain prescription drugs.

14 Oct 2019

Study highlights role of patient maximizing-minimizing preferences in thyroid cancer surveillance

Not all patients feel the same way about medical treatment. Some are "minimizers," preferring to see a doctor as little as possible and to give health issues a chance to resolve on their own. Others are "maximizers" who want to treat a disease to the fullest extent possible, even if doesn't make a big difference in the overall outcome.

14 Oct 2019

Advancements in the use of AI in Oncology explored at Cleveland

Artificial Intelligence, machine learning and smart computing are all rapidly transforming the global health and medical landscape, including at Case Western Reserve University and among its health-care partners in Northeast Ohio and beyond.

14 Oct 2019

Novel clinical trial to examine use of cannabidiol in people with Parkinson's-related psychosis

A pioneering clinical trial will investigate the use of cannabidiol (CBD) - a compound found in the cannabis plant - in people with Parkinson's-related psychosis.

14 Oct 2019

Ophthalmologists find more evidence linking common bladder drug to retinal conditions

A drug widely prescribed for a bladder condition for decades, now appears to be toxic to the retina, the light sensing tissue at the back of the eye that allows us to see.

14 Oct 2019

Impress your boss with this course

In this webinar, Dr. Michael W. Dong, Pittcon Short Course Instructor, will review best practices, short cuts, and tricks-of-the-trade to help pharmaceutical and other scientists to become more successful in developing effective HPLC methods (potency and ICH-compliant stability-indicating assays) using method templates and universal generic gradient methods.

From Pittcon 14 Oct 2019

Coffee beans show promise in fighting inflammation, insulin resistance

Coffee has long been proven to provide many health benefits. Aside from its ability to keep us awake throughout the day, it is packed with antioxidants that ward off free radicals.

14 Oct 2019

Caution urged in reducing opioids for pain

After years and decades in which healthcare providers were freely prescribing opiates for all sorts of painful conditions, the US Centers for Disease Control and Prevention (CDC) published guidelines to help bring down opioid prescription rates and with them, addiction and overdose-related death rates. Though these were not binding, they urged physicians to be cautious in dealing with opioids when prescribing for pain.

13 Oct 2019

Popcorn packaging contains high levels of toxic chemicals

Many chemicals used at home and in various industries use per- and polyfluoroalkyl substances (PFAS). Several studies have traced these substances in materials used for packaging foods, such as microwavable bags and food containers.

13 Oct 2019

Rotavirus plays role in development of type 1 diabetes

A new article published in the journal PLOS Pathogens on October 10, 2019, claims that the common rotavirus may be responsible for the occurrence of type 1 diabetes, a form of diabetes which occurs in children and is due to destruction of the pancreatic islet cells that produce the hormone insulin to normalize blood glucose levels.

13 Oct 2019

Prescription drug nonadherence linked to food insecurity, study shows

Food insecurity is linked to higher disease rates but not much is known about the reasons for this. A new study of more than 10,000 Canadian households shows that this connection may be at least partially attributed to lack of access to prescription medication.

11 Oct 2019