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Combination therapy is safe and effective for older patients diagnosed with acute lymphoblastic leukemia

A study led by The University of Texas MD Anderson Cancer Center showed that treatment combining lower doses of chemotherapy with the monoclonal antibody inotuzumab ozogamicin (INO), with or without the drug blinatumomab, is safe and effective in patients over 60 years of age who were newly diagnosed with a high-risk form of acute lymphoblastic leukemia (ALL) known as Philadelphia chromosome-negative ALL.

10 Dec 2019

Rutgers researchers identify small mutations for AML and MDS through deep DNA sequencing

Deep DNA sequencing analysis conducted by Rutgers Cancer Institute of New Jersey investigators examining genomic differences within tumors for prediction of disease relapse in certain hematologic malignancies has identified small mutations.

9 Dec 2019

Retrospective review: Proton therapy well tolerated in patients undergoing breast conserving surgery

While the assessment of proton therapy in breast cancer treatment continues through clinical trials, data relating to early toxicity and cosmetic outcomes for this population are limited.

9 Dec 2019

Common antibiotic appears to boost the effect of radiation on tumor cells

The antibiotic vancomycin alters the gut microbiome in a way that can help prime the immune system to more effectively attack tumor cells after radiation therapy.

9 Dec 2019

Mapping genetic links between diseases using data from electronic health records

Physicians use standard disease classifications based on symptoms or location in the body to help make diagnoses. These classifications, called nosologies, can help doctors understand which diseases are closely related, and thus may be caused by the same underlying issues or respond to the same treatments.

9 Dec 2019

New strategies needed to manage ibrutinib-related toxicities in CLL patients, study suggests

New findings by Yale Cancer Center and Smilow Cancer Hospital researchers show that as the use of the drug ibrutinib climbs in patients with chronic lymphocytic leukemia, so do the rates of patients who stop taking the drug.

9 Dec 2019

'Achilles' heel' of deadly superbug identified

A deadly superbug that infects an estimated 54,500 Americans a year has a secret weapon, a protein, that allows it to defy antibiotic treatment and immune system attacks.

9 Dec 2019

Experts publish new book with recommendations to reduce Latino cancer

As U.S. Latinos face a staggering 142% projected rise in cancer cases by 2030, UT Health San Antonio leaders gathered international cancer experts to publish a new book with innovative research and recommendations to reduce Latino cancer.

9 Dec 2019

Researchers receive federal grant to study educational outcomes of children with special needs

A team of New Jersey researchers received a major federal grant to study the educational outcomes of children with special health care needs.

9 Dec 2019

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

Researchers demonstrated that Lactobacillus rhamnosus can dose-dependently reestablish a balanced intestinal microbiome and counter the liver-damaging effects of alcohol consumption in mice to reverse the results of chronic alcohol-induced liver injury.

9 Dec 2019

Study uses machine learning and health data to identify suicide risk factors

First-of-its-kind study used machine learning and health data from the entire Danish population to create sex-specific suicide risk profiles, illuminating the complex mix of factors that may predict suicide.

9 Dec 2019

Relapsed mantle cell lymphoma patients may benefit from CAR T-cell therapy

A one-year follow-up study led by The University of Texas MD Anderson Cancer Center revealed a majority of patients with mantle cell lymphoma resistant to prior therapies may benefit from treatment with CD19-targeting chimeric antigen receptor (CAR) T-cell therapy.

9 Dec 2019

Medical errors: Many patients today still aren’t safe

In 1999, the Institute of Medicine issued To Err Is Human, a 300-page declaration of a crisis in patient safety.

9 Dec 2019

Stem cell transplant following treatment with PD-1 inhibitor is safe, effective for patients with Hodgkin lymphoma

A new analysis shows that a donor stem cell transplant following treatment with an immune checkpoint inhibitor is generally safe and produces good outcomes for patients with Hodgkin lymphoma, easing concerns that these patients are at heightened risk for severe immune-related complications.

9 Dec 2019

Aspirin may no longer provide benefit as primary prevention for cardiovascular disease

A new paper in Family Practice, published by Oxford University Press, found that the widespread use of statins and cancer screening technology may have altered the benefits of aspirin use.

9 Dec 2019

Dead probiotic reduces age-related leaky gut in older mice, study finds

Scientists at Wake Forest School of Medicine have identified a dead probiotic that reduces age-related leaky gut in older mice. The study is published in the journal GeroScience.

9 Dec 2019

Penn researchers receive nearly $5 million to reduce opioid cravings

Opioid overdoses take the lives of tens of thousands of Americans annually. Two researchers from Penn State College of Medicine have received nearly $5 million from the National Institutes of Health to study whether an already-approved drug can be used to reduce cravings and prevent relapse in those struggling with opioid addiction.

9 Dec 2019

New software tool uses AI to recognize cancer cells from digital pathology images

UT Southwestern researchers have developed a software tool that uses artificial intelligence to recognize cancer cells from digital pathology images - giving clinicians a powerful way of predicting patient outcomes.

9 Dec 2019

New nanoparticle innovation detects vascular calcification in atherosclerosis

Heart disease and stroke are the world's two most deadly diseases, causing over 15 million deaths in 2016 according to the World Health Organization.

9 Dec 2019

Pairing chemotherapy azacitidine with enasidenib boosts complete remission in AML patients

A multi-institutional, Phase II study led by The University of Texas MD Anderson Cancer Center showed that pairing standard chemotherapy azacitidine (AZA) with a drug called enasidenib (ENA) measurably boosts complete remission in patients newly diagnosed with a specific form of acute myeloid leukemia (AML).

9 Dec 2019

Medical News

Combination therapy is safe and effective for older patients diagnosed with acute lymphoblastic leukemia

Rutgers researchers identify small mutations for AML and MDS through deep DNA sequencing

Retrospective review: Proton therapy well tolerated in patients undergoing breast conserving surgery

Common antibiotic appears to boost the effect of radiation on tumor cells

Mapping genetic links between diseases using data from electronic health records

New strategies needed to manage ibrutinib-related toxicities in CLL patients, study suggests

'Achilles' heel' of deadly superbug identified

Experts publish new book with recommendations to reduce Latino cancer

Researchers receive federal grant to study educational outcomes of children with special needs

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

Study uses machine learning and health data to identify suicide risk factors

Relapsed mantle cell lymphoma patients may benefit from CAR T-cell therapy

Medical errors: Many patients today still aren’t safe

Stem cell transplant following treatment with PD-1 inhibitor is safe, effective for patients with Hodgkin lymphoma

Aspirin may no longer provide benefit as primary prevention for cardiovascular disease

Dead probiotic reduces age-related leaky gut in older mice, study finds

Penn researchers receive nearly $5 million to reduce opioid cravings

New software tool uses AI to recognize cancer cells from digital pathology images

New nanoparticle innovation detects vascular calcification in atherosclerosis

Pairing chemotherapy azacitidine with enasidenib boosts complete remission in AML patients

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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