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Therapeutic implications of caffeine in neuropsychiatric disorders

An important new article reviews recently discovered properties of adenosine A2A receptor-dopamine D2 receptor and adenosine A1 receptor-dopamine D1 receptor heteromers--both of which are main targets for caffeine--and discusses the therapeutic implications of these findings.

7 Jan 2019

UC researchers receive $3.2 million grant to study stroke recurrence risk

Researchers at the University of Cincinnati have received a $3.2 million grant from the National Institute of Neurological Diseases to study the use of neuroimaging to pinpoint the risk factors of stroke recurrence.

7 Jan 2019

First patient enrolled in pancreatic cancer clinical trial

The Henry Ford Cancer Institute announced today it has enrolled the first patient in a new clinical trial to test the effectiveness of using precise, higher dose MRI-guided radiation therapy to treat pancreatic cancer.

7 Jan 2019

New findings from a safety and feasibility clinical trial on removal of senescent cells

Mayo Clinic researchers, along with collaborators from Wake Forest School of Medicine and the The University of Texas Health Sciences Center at San Antonio, have published findings from a safety and feasibility clinical trial on the removal of senescent cells from a small group of patients with pulmonary fibrosis

7 Jan 2019

Researchers identify genetic risk factor for atypical heart attack in women

New research published by teams from Leicester, UK and Paris, France in collaboration with international partners from the US and Australia, has found a common genetic factor that confers a significant risk of atypical heart attacks in women.

7 Jan 2019

Noninvasive hearing test may assist with early detection of autism spectrum disorders

A noninvasive hearing test may assist with early detection and diagnosis of autism spectrum disorders, according to research published in the Journal of the American Osteopathic Association.

7 Jan 2019

Cellular protein signal can be manipulated to favor bone building

In experiments in rats and human cells, Johns Hopkins Medicine researchers say they have added to evidence that a cellular protein signal that drives both bone and fat formation in selected stem cells can be manipulated to favor bone building.

7 Jan 2019

USC research could lay foundation for a vaccine against tick-borne virus

Two groundbreaking discoveries by USC researchers could lead to medications and a vaccine to treat or prevent a hemorrhagic fever transmitted by a new tick species before it spreads across the United States.

7 Jan 2019

Study of rare uterine sarcoma reveals clinically relevant molecular subtypes

Undifferentiated uterine sarcoma is a very rare but extremely aggressive cancer type. It can be divided into four groups with different characteristics of clinical importance - a new study at Karolinska Institutet reveals.

7 Jan 2019

Faulty immune receptor in HIV patients could be reason why many experience complications

For HIV patients, treatments that control the infection have come a long way. But many still struggle with a host of other disease-related complications such as neurocognitive disorders, cardiovascular issues, diabetes and chronic inflammation.

7 Jan 2019

Opioids contribute to rise in suicides and overdoses in the U.S.

Suicides and drug overdoses kill American adults at twice the rate today as they did just 17 years ago, and opioids are a key contributor to that rise, according to a new review and analysis by a University of Michigan team.

7 Jan 2019

Scientists identify new bat-borne virus related to Ebola

Researchers from Singapore's Duke-NUS Medical School, in collaboration with scientists in China, have identified and characterized a new genus of filovirus from a Rousettus bat in China. Their findings were published in the journal Nature Microbiology.

7 Jan 2019

Johns Hopkins researchers identify new marker for early detection of colorectal cancers

Johns Hopkins researchers have identified a protein involved in cell proliferation and the development of new blood vessels that could serve as a marker for the early detection of colorectal cancers.

7 Jan 2019

First viable mouse model of Hirschsprung's disease developed

About one in every 5,000 babies is born without enteric neurons in distal colon resulting in Hirschsprung's disease. Because of the lacking neurons, contents of the gut cannot pass normally resulting in constipation and enlargement of colon.

7 Jan 2019

Study confirms increased pneumonia risk with prescription opioids

A study led by researchers at Yale University has shown that taking prescribed opioids increases the risk of pneumonia, irrespective of HIV status.

7 Jan 2019

Alzheimer's pathophysiology shows racial disparities

A study has identified racial disparities between African-Americans and Caucasians in the way in which Alzheimer’s disease arises and develops.

7 Jan 2019

Cervical cancer screening rates are unacceptably low, finds Mayo Clinic study

The percentage of women who are screened for cervical cancer may be far lower than national data suggests, according to a Mayo Clinic study recently published in the Journal of Women's Health. Less than two-thirds of women ages 30 to 65 were up-to-date with cervical cancer screenings in 2016.

7 Jan 2019

New bioinspired material interacts with surrounding tissues to promote wound healing

Imperial researchers have developed new bioinspired material that interacts with surrounding tissues to promote healing.

7 Jan 2019

Medicaid plans cover doctors’ visits, hospital care — and now your GED

Emilia Ford became pregnant at 15 and, after her daughter was born, dropped out of high school.

7 Jan 2019

Genes are involved in development of atrial fibrillation

Atrial fibrillation is the most common form of heart arrhythmia. About ten per cent of everyone over age 75 develop this condition, in which the two upper chambers of the heart (the atria) beat much faster than the main chambers (the ventricles), creating a fluttering feeling in the chest.

7 Jan 2019