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Brigatinib drug may offer first-line treatment option for ALK-positive NSCLC

Results of a 275-patient, multi-national phase III clinical trial known as ALTA-1L published today in the New England Journal of Medicine and presented concurrently in the press program at the International Association for the Study of Lung Cancer (IASLC) World Conference on Lung Cancer 2018 argue for brigatinib as a first-line treatment option for advanced ALK-positive non-small cell lung cancer.

26 Sep 2018

VRK1 protein may enable cancer cells to colonize new areas of the body during metastasis

Sometimes negative results can point researchers in the right direction. In results published in PLOS ONE on September 4, 2018, scientists at the Medical University of South Carolina examined a protein called vaccinia-related kinase 1 that they hypothesized was important for metastasis. They found that, rather than causing cancer cells to migrate and invade, VRK1 over-expression had the opposite effect.

26 Sep 2018

Alzheimer’s disease researchers makes significant breakthroughs

Researchers in Sweden and United Kingdom have made a breakthrough in Alzheimer’s disease research. They could soon be on the path to develop new drugs that could fight the disease more effectively.

26 Sep 2018

Pathogenic bacteria hibernate to escape antibiotic treatments

BACTERIA University of Copenhagen researchers have discovered a surprising tactic of pathogenic bacteria when being attacked by antibiotics: hibernation.

26 Sep 2018

New born syphilis on the rise sparking concerns

Congenital syphilis or new born syphilis occurs in the new born baby when the mother is affected with the syphilis bacteria during pregnancy or delivery and passes it on to her baby. A new report that was released this Tuesday (25th September 2018) by the US Centres for Disease Control and Prevention (CDC) that showed that in the US, the numbers of these new born syphilis cases have doubled since 2013.

26 Sep 2018

New TB vaccine effective in half of the population in phase II trials

GlaxoSmithKline has come up with an experimental vaccine against tuberculosis (TB) that has shown effective prevention of the infection in half of the population it has been administered to. This could be a breakthrough in preventing the killer disease say researchers since most of the recent vaccines developed against the disease have failed to show efficacy.

26 Sep 2018

Prostatectomy plus radiotherapy associated with greater survival in prostate cancer patients

High-risk prostate cancer, that which has continued to grow but not yet metastasized, is commonly treated with combination therapies. Each method has pros and cons, but there is little clarity whether one might be more effective than the other.

25 Sep 2018

Hybrid operating room enables faster diagnosis, treatment of patients with lung cancer

Representing a paradigm shift in thoracic surgery, the hybrid operating room combines three techniques into a single appointment eliminating multiple clinical visits for improved patient experience and outcomes.

25 Sep 2018

UCI study finds new cause of cerebral microbleeds

A team of researchers including UCI project scientist Rachita Sumbria, PhD and UCI neurologist Mark J. Fisher, MD have provided, for the first time, evidence that blood deposits in the brain may not require a blood vessel tear.

25 Sep 2018

Driver gene mutations found to be common for cancer metastases

Driver genes in different metastases from the same patient are remarkably similar, providing optimism for the success of future targeted therapies, according to a published study by Science.

25 Sep 2018

Novel drug alleviates memory deficits and neuropathology in Alzheimer's animal model

New research conducted at the Lady Davis Institute at the Jewish General Hospital reveals that a novel drug reverses memory deficits and stops Alzheimer disease pathology in an animal model.

25 Sep 2018

Study reveals connection between hunger and mood

It seems "hangry" isn't just a made-up term. University of Guelph researchers have revealed that the sudden drop in glucose we experience when we are hungry can impact our mood.

25 Sep 2018

Increased physical activity associated with improvement in IBS symptoms

Increased physical activity is now being emphasized as a treatment option for the gastric intestinal disease known as IBS. Research at Sahlgrenska Academy, Sweden, indicates improvements in both intestinal function and self-esteem of patients who exercise more.

25 Sep 2018

Patients with paralysis manage to walk thanks to new technology

Two of four participants in a study conducted at the Kentucky Spinal Cord Injury Research Center at the University of Louisville (UofL) have managed to walk over ground after having suffered traumatic complete spinal cord injury.

25 Sep 2018

New model enables anyone to run powerful simulations, complex calculations easily

Imagine a world in which complex calculations that could help improve someone’s health, clean up our planet or test an entrepreneur’s big idea don’t require specific skills.

25 Sep 2018

Study analyzes quality of protein supplements in function of source, treatment and storage

Powdered protein supplements are one of the most commonly consumed nutritional supplements, whether by professional sportspeople or amateurs, even by those who use them for aesthetic purposes instead of sporting ones.

25 Sep 2018

FDA grants Orphan Drug Designation to Myelo001 for treatment of Acute Radiation Syndrome

Myelo Therapeutics GmbH announced today that the US Food and Drug Administration has granted an Orphan Drug Designation to its orally applied new chemical entity Myelo001 for the treatment of Acute Radiation Syndrome.

25 Sep 2018

NeoTract presents new clinical data from studies of UroLift System for patients with BPH

NeoTract, a wholly owned subsidiary of Teleflex Incorporated focused on addressing unmet needs in the field of urology, today announced the presentation of new clinical data at the World Congress of Endourology 2018 Annual Conference from two U.K. studies of the company's novel UroLift System for patients with Benign Prostatic Hyperplasia.

25 Sep 2018

5 things to know about Trump’s new ‘public charge’ immigration proposal

A proposed rule from the White House would make it harder for legal immigrants to get green cards if they have received certain kinds of public assistance — including Medicaid, food stamps and housing subsidies. Green cards allow them to live and work permanently in the United States.

25 Sep 2018

Cerevance starts dosing in Phase I clinical trial of CVN424 for treatment of Parkinson's disease

Cerevance, a clinical-stage drug discovery and development company focused on brain diseases, today announced the start of dosing in a Phase I first-in-human clinical trial of CVN424, an oral compound being developed for symptomatic treatment of Parkinson's disease.

25 Sep 2018

Medical News

Brigatinib drug may offer first-line treatment option for ALK-positive NSCLC

VRK1 protein may enable cancer cells to colonize new areas of the body during metastasis

Alzheimer’s disease researchers makes significant breakthroughs

Pathogenic bacteria hibernate to escape antibiotic treatments

New born syphilis on the rise sparking concerns

New TB vaccine effective in half of the population in phase II trials

Prostatectomy plus radiotherapy associated with greater survival in prostate cancer patients

Hybrid operating room enables faster diagnosis, treatment of patients with lung cancer

UCI study finds new cause of cerebral microbleeds

Driver gene mutations found to be common for cancer metastases

Novel drug alleviates memory deficits and neuropathology in Alzheimer's animal model

Study reveals connection between hunger and mood

Increased physical activity associated with improvement in IBS symptoms

Patients with paralysis manage to walk thanks to new technology

New model enables anyone to run powerful simulations, complex calculations easily

Study analyzes quality of protein supplements in function of source, treatment and storage

FDA grants Orphan Drug Designation to Myelo001 for treatment of Acute Radiation Syndrome

NeoTract presents new clinical data from studies of UroLift System for patients with BPH

5 things to know about Trump’s new ‘public charge’ immigration proposal

Cerevance starts dosing in Phase I clinical trial of CVN424 for treatment of Parkinson's disease

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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