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Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

A single dose of mesenchymal stem cells delivered intravenously to patients with chronic non-ischemic cardiomyopathy was not associated with significant cardiac structural or functional improvements, but did result in several clinically relevant benefits, according to results from a phase II-a randomized trial.

29 Aug 2016

Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

BRAF mutation occurs in between 40% and 50% of metastasising melanomas (skin cancers), boosting tumour growth.

29 Aug 2016

PCSK9 inhibitor can reduce need for apheresis treatment in patients with familial hypercholesterolemia

Patients who have heterozygous familial hypercholesterolemia (HeFH), a condition that causes abnormally raised low-density lipoprotein cholesterol (LDL-C) levels and premature cardiovascular disease, can significantly reduce or even eliminate their need for expensive and time-consuming apheresis treatments with the PCSK9 inhibitor alirocumab.

29 Aug 2016

Large cardiopoietic regenerative therapy trial for patients with congestive heart failure reveals new insights

A therapy that uses bone-marrow stem cells to promote heart repair did not significantly improve the primary outcome over a sham procedure among patients with congestive heart failure.

29 Aug 2016

An Introduction to Specialty Pharmaceuticals

In this interview, News Medical talks to David Moran, Managing Director of Clinigen SP about specialty pharmaceuticals.

From Clinigen Group 29 Aug 2016

Cleft palate repair costs the same for internationally adopted children

Since 2009, United States residents have adopted more children from China than any other country. Since China has a high prevalence of cleft lip and palate, some of these children require extra medical care early in their lives. Many prospective families are fearful of the treatment costs needed by a child affected by cleft lip and palate. However, recent research suggests that the costs are not nearly as high as previously thought.

29 Aug 2016

Each NHS hospital admission linked to 2% increased risk of death for heart failure patients

Heart failure patients have a 2% increased risk of dying with each admission to NHS hospitals, according to research presented at ESC Congress 2016 today.

29 Aug 2016

Waiting impulsivity may help spot offspring of alcoholics at risk for developing alcohol addiction

Researchers know that youth with a family history of alcoholism have a greater risk of developing an alcohol use disorder; this heightened vulnerability may be due to impulsive behavior.

29 Aug 2016

Occasional medicine users not getting the full benefits of their medicines

Survey findings released for Be Medicinewise Week (22-28 August) have revealed that occasional users of medicines—including prescription, over-the-counter, and alternative or complementary forms of medicines—are potentially not getting the full benefits from their medicines, compared to people who take medicines more often.

29 Aug 2016

Cases of rotavirus infections fall by 84% thanks to vaccination

Figures published by Public Health England have shown that the number of diagnosed Rotavirus cases, a highly infectious virus which may cause vomiting and diarrhoea, have dropped by 84% since the introduction of a vaccine to the national childhood immunisation schedule in July 2013.

29 Aug 2016

Is the virtual gene panel the way forward asks Congenica at Dx Summit

Although the current practice of analysing defined gene panels for a specific disease has great utility, it is of limited benefit when a condition is not well defined.

29 Aug 2016

Blacktrace launches Particle Works, a nano- and microstructure specialist brand

Blacktrace Holdings Limited, a leading group of companies focused on Productizing Science®, will be launching its latest brand, Particle Works, at the NANOTEXNOLOGY 2016 conference in Thessaloniki, Greece, from the 4th to the 8th of July. The Blacktrace group’s many years of expertise and world-leading capabilities in the design, development and manufacture of automated microfluidic continuous flow equipment provide the perfect foundation for this newly created brand specializing in high performance nano- and microstructured materials.

29 Aug 2016

Leading Chikungunya vaccine in clinical trial phase 2

With the first patient vaccinated, a Phase 2 clinical trial of a promising prophylactic vaccine candidate against Chikungunya fever has now commenced. The product is the most advanced Chikungunya vaccine candidate globally and is developed by the Austrian biotech company Themis Bioscience GmbH.

29 Aug 2016

Dr Google is here to stay - so how do you do it safely?

Almost four out of five Australians (78%) report that they look for information about medicines on the internet, according to a new 2016 survey* released during Be Medicinewise Week (22-28 August).

29 Aug 2016

Blade implants in oral surgery still successful after 50 years

Journal of Oral Implantology – For nearly 50 years, the unique design of the blade implant and the ease of inserting it into a patient’s mouth have made it popular among oral surgeons. As the implant’s golden jubilee approaches, some of its original designers take a new look at a creation that has “passed the test of time.”

29 Aug 2016

Ethicon partners with Touch Surgery to improve global surgical training

Ethicon, Inc., part of the Johnson & Johnson Medical Devices Companies, announces a strategic collaboration with Touch Surgery to help improve patient outcomes by delivering simulated surgical training based on the safe and efficacious use of Ethicon products in a free mobile app that can reach medical professionals in even remote regions of the world.

29 Aug 2016

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

Janssen-Cilag International NV has announced the submission of a Type II variation application to the European Medicines Agency (EMA), seeking to broaden the existing marketing authorisation for the immunotherapy DARZALEX® (daratumumab) to include treatment of adult patients with relapsed multiple myeloma who have received at least one prior therapy. The expanded indication is based on daratumumab in combination with lenalidomide (an immmunomodulatory agent) and dexamethasone, or bortezomib (a PI) and dexamethasone.

29 Aug 2016

Boehringer Ingelheim and Duke expand collaboration to create largest patient registry for idiopathic pulmonary fibrosis (IPF)

Boehringer Ingelheim Pharmaceuticals, Inc. and the Duke Clinical Research Institute (DCRI) announced today the expansion of the Idiopathic Pulmonary Fibrosis – PROspective Outcomes (IPF-PRO) Registry, a patient registry developed to uncover insights into IPF, a rare and serious lung disease. The expansion will increase the study enrollment from 300 patients at 18 study sites to 1,500 patients at approximately 45 sites, creating the largest registry of newly diagnosed IPF patients.

29 Aug 2016

Study results confirm safety and efficacy of INSIGHTEC’s Exablate Neuro system for the treatment of essential tremor

INSIGHTEC, the leader in MR-guided Focused Ultrasound (MRgFUS) therapy, has announced that the New England Journal of Medicine (NEJM) has published the results of a pivotal study of their Exablate Neuro system for the non-invasive treatment of essential tremor (ET). The study met its primary endpoint with patients treated with Exablate Neuro demonstrating a clinically significant 47% improvement in a composite tremor score at three months as compared to no change in the sham cohort.

29 Aug 2016

Research shows AEDs fail to save lives without basic life support education

Automatic external defibrillators (AEDs) fail to save lives when the public does not have basic life support education, according to research presented today at ESC Congress 2016.

29 Aug 2016

Medical News

Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

PCSK9 inhibitor can reduce need for apheresis treatment in patients with familial hypercholesterolemia

Large cardiopoietic regenerative therapy trial for patients with congestive heart failure reveals new insights

An Introduction to Specialty Pharmaceuticals

Cleft palate repair costs the same for internationally adopted children

Each NHS hospital admission linked to 2% increased risk of death for heart failure patients

Waiting impulsivity may help spot offspring of alcoholics at risk for developing alcohol addiction

Occasional medicine users not getting the full benefits of their medicines

Cases of rotavirus infections fall by 84% thanks to vaccination

Is the virtual gene panel the way forward asks Congenica at Dx Summit

Blacktrace launches Particle Works, a nano- and microstructure specialist brand

Leading Chikungunya vaccine in clinical trial phase 2

Dr Google is here to stay - so how do you do it safely?

Blade implants in oral surgery still successful after 50 years

Ethicon partners with Touch Surgery to improve global surgical training

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

Boehringer Ingelheim and Duke expand collaboration to create largest patient registry for idiopathic pulmonary fibrosis (IPF)

Study results confirm safety and efficacy of INSIGHTEC’s Exablate Neuro system for the treatment of essential tremor

Research shows AEDs fail to save lives without basic life support education

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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