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Neuroscientists decipher new pathway in stem cell differentiation

How do neurons become neurons? They all begin as stem cells, undifferentiated and with the potential to become any cell in the body.Until now, however, exactly how that happens has been somewhat of a scientific mystery. New research conducted by UC Santa Barbara neuroscientists has deciphered some of the earliest changes that occur before stems cells transform into neurons and other cell types.

25 Mar 2016

Speech-controlled nutrition-logging system may help lose weight

For people struggling with obesity, logging calorie counts and other nutritional information at every meal is a proven way to lose weight. The technique does require consistency and accuracy, however, and when it fails, it's usually because people don't have the time to find and record all the information they need.

25 Mar 2016

DNA sequence features predict genome-wide binding pattern of key protein involved in brain disorders

Researchers from the University of Illinois at Urbana-Champaign and the University of California-Davis are combining in vivo experimentation with computation for highly accurate prediction of the genome-wide binding pattern of a key protein involved in brain disorders.

25 Mar 2016

Wnt secretion inhibitors may reduce renal fibrosis

Renal fibrosis or the scarring of kidneys, following an injury, reduces their function and can cause kidney disease to progressively worsen.

25 Mar 2016

European Obesity Day to focus on growing obesity epidemic

The growing obesity epidemic, which is predicted to affect more than half of all European citizens by 2030, will be the focus of European Obesity Day to be held on 21 May.

25 Mar 2016

Findings could help explain origin of type 2 diabetes in children of obese mothers

A new study led by researchers at The Saban Research Institute of Children's Hospital Los Angeles reports that the presence of leptin - a hormone secreted by fat cells that is critical to maintaining energy balance in the body -- inhibits the prenatal development of neuronal connections between the brain and pancreas. The findings could help explain the origin of type 2 diabetes, particularly in children of obese mothers.

25 Mar 2016

Lancet experts call for evidence-based approach to drug policy

Fifty years of drug policies aimed at restricting and criminalizing drug use and minor possession have had serious detrimental effects on the health, wellbeing and human rights of drug users and the wider public, according to a major new report by The Lancet and Johns Hopkins University in the US

25 Mar 2016

Personalized medicine promises better treatment options for cystic fibrosis patients

For a highly variable disease like cystic fibrosis, personalized medicine promises treatments based on individual factors, down to the molecular level. This promise is especially alluring for the treatment of children with cystic fibrosis, who are at particular risk for complications that could affect them throughout their lives.

25 Mar 2016

Study gives insight into reasons behind hospital deaths in older people

Despite the rates of hospital deaths in England declining, nearly two-thirds of people aged 85 and over, and more than half of people aged 95 and over still die in hospital, new research has found.

25 Mar 2016

Self-repairing cancer cells: A new pathway for cancer treatment

With narrow bodies and no collarbones, mice are able to squeeze through holes as small as a quarter-inch in diameter. Cancer cells similarly are able to migrate through extremely tight quarters but with a major difference: The journey often comes at a price - the deformation and, in some cases, rupture of the outer lining of a cell's nucleus. While deformation and rupture can sometimes lead to cell death, the cell - about 90 percent of the time - also has the ability to repair itself.

25 Mar 2016

Social microvolunteering app could support Alzheimer's caregivers

Every day, more than 15 million unpaid caregivers provide care to people with Alzheimer's disease, with little outside support and often at the risk of their own health.

25 Mar 2016

New research highlights potential for emergence of new form of Ebolavirus

New research at the University of Kent has highlighted the potential for the emergence of a new form of Ebolavirus. A team from the University's School of Biosciences examined the differences between Ebolaviruses that cause severe disease in humans and the Reston virus that does not.

25 Mar 2016

Study shows preterm born individuals at risk of lower health-related quality of life

Parents of very premature babies are more worried about their grown up children's lives than mothers and fathers whose babies were born full term.

25 Mar 2016

Penn chemists find potential ways to use methane in pharmaceuticals, value-added substances

Methane is the world's most abundant hydrocarbon. It's the major component of natural gas and shale gas and, when burned, is an effective fuel. But it's also a major contributor to climate change, with 24 times greater potency as a greenhouse gas than carbon dioxide.

25 Mar 2016

Penn’s CHW model can now be used in outpatient settings

Penn's Innovative Community Health Worker (CHW) model, shown to reduce admissions and lead to better health outcomes for hospitalized patients, can now be used in outpatient settings, according to a study from researchers at the Perelman School of Medicine in the journal Population Health Management.

25 Mar 2016

Technically poor root fillings linked to stress and economy

Only half of all root fillings that are done in the Swedish public dental service are of good quality. The reason that dentists accept technically poor root fillings can be that they feel root fillings are difficult, associate them with stress and frustration as well as that a good quality root treatment often takes longer than what the dental care tariff allots as compensation.

25 Mar 2016

Incretin-based drugs do not increase risk of heart failure

Incretin-based drugs, a type of medication used to treat type 2 diabetes, do not increase the risk of being hospitalized for heart failure relative to commonly used combinations of oral anti-diabetic drugs, according to a new study published in the New England Journal of Medicine.

25 Mar 2016

Restrictions to opioid prescription block their use for safe, effective pain relief

Opioids are very effective for treating some types of pain, such as cancer pain and postoperative pain, but not for other kinds of pain like chronic low back pain. An increase in the number of opioid-related deaths among addicts has led to the current movement to restrict opioid prescribing by state and federal authorities.

25 Mar 2016

Computational method helps assess patient-specific progression of osteoarthritis in knee joint

Osteoarthritis is a degenerative disease in which the articular cartilage protecting the joint starts to degenerate and wear off over time. The main risk factors of osteoarthritis are advanced age and overweight-induced significant stresses on the knee joint.

25 Mar 2016

Lack of UBE3A gene causes Angelman syndrome

The gene UBE3A plays a critical role in early neurological development. If UBE3A is overexpressed - or if the enzymatic function of UBE3A protein is hyperactive - autism ensues. A lack of functional UBE3A causes Angelman syndrome (AS), a neurodevelopmental disorder characterized by severe developmental delay, motor deficits, absence of speech, and, in most cases, epilepsy.

25 Mar 2016

Medical News

Neuroscientists decipher new pathway in stem cell differentiation

Speech-controlled nutrition-logging system may help lose weight

DNA sequence features predict genome-wide binding pattern of key protein involved in brain disorders

Wnt secretion inhibitors may reduce renal fibrosis

European Obesity Day to focus on growing obesity epidemic

Findings could help explain origin of type 2 diabetes in children of obese mothers

Lancet experts call for evidence-based approach to drug policy

Personalized medicine promises better treatment options for cystic fibrosis patients

Study gives insight into reasons behind hospital deaths in older people

Self-repairing cancer cells: A new pathway for cancer treatment

Social microvolunteering app could support Alzheimer's caregivers

New research highlights potential for emergence of new form of Ebolavirus

Study shows preterm born individuals at risk of lower health-related quality of life

Penn chemists find potential ways to use methane in pharmaceuticals, value-added substances

Penn’s CHW model can now be used in outpatient settings

Technically poor root fillings linked to stress and economy

Incretin-based drugs do not increase risk of heart failure

Restrictions to opioid prescription block their use for safe, effective pain relief

Computational method helps assess patient-specific progression of osteoarthritis in knee joint

Lack of UBE3A gene causes Angelman syndrome

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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