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Maternal immune dysfunction linked to risk of autism with intellectual disability in children

Pregnant women with higher levels of inflammatory cytokines and chemokines, proteins that control communication between cells of the immune system, may be at significantly greater risk of having a child with autism combined with intellectual disability, researchers with the UC Davis MIND Institute have found.

8 Jun 2016

Maternal topiramate use in conjunction with other anti-epileptic drugs may cause fetal malformations

In an analysis of pregnancies in Australia from 1999 to 2014 in which women were taking anti-epileptic drugs, fetal malformation rates fell over time in pregnancies where only one drug was taken, but rates increased in pregnancies where multiple drugs were taken.

8 Jun 2016

Study challenges notion of fear of weight gain in patients with anorexia nervosa

A study from Inserm, Paris Descartes University and Sainte Anne Hospital suggests that anorexia nervosa might not be explained by fear of gaining weight, but by the pleasure of losing it... and that the phenomenon might be genetically influenced.

8 Jun 2016

Common angina drug can stimulate patient's own white blood cells to combat cryptococcosis

A drug, more commonly used in the treatment of angina, could be the focus of a new strategy in fighting the fatal fungal infection cryptococcosis

8 Jun 2016

First European fully superconductive coil reaching a magnetic field of 25 Tesla produced

Today, the magnets used in nuclear magnetic resonance (NMR) and medical magnetic resonance imaging (MRI) represent the primary commercial applications of superconductivity. NMR, used mainly in the chemical and pharmaceutical industry, allows discovering new molecules, studying the structure of proteins or analyzing food content. It is essential for drug development or the quality control of chemical compounds.

From Bruker BioSpin Division 8 Jun 2016

PREDIMED study weighs in to dietary fat discussion

A prespecified analysis of the PREDIMED study suggests that an increase in the proportion of calories consumed as fat in the context of a Mediterranean-style diet does not have an adverse effect on bodyweight.

8 Jun 2016

Post-CABG hospital stays longer in severely obese patients

Severely obese patients have longer hospital stays after coronary artery bypass grafting than patients with normal body mass index, which may be due to their increased infection risk, Canadian researchers report.

8 Jun 2016

TAVI matches SAVR for early and midterm mortality

Transcatheter aortic valve implantation has similar early and midterm mortality to surgical aortic valve replacement in patients with aortic stenosis, including those at low to intermediate risk, show results of a systematic review and meta-analysis.

8 Jun 2016

Cerebral microbleeds warn of dementia risk

A high cerebral microbleed count increases an individual's risk of cognitive deterioration and dementia, study results indicate.

8 Jun 2016

Unsafe antiplatelet use persists in PCI patients

Contraindicated antiplatelet use is rare but persists in patients undergoing percutaneous coronary intervention, show US study data.

8 Jun 2016

Subcutaneous treatment with cord blood stem cells improves eczema symptoms

A new study suggests that treatment with stem cells from umbilical cord blood might be an effective therapy for patients with moderate-to-severe eczema, or atopic dermatitis.

7 Jun 2016

Mice implanted with human glia cells exhibit reduced symptoms of Huntington's disease

Researchers have successfully reduced the symptoms and slowed the progression of Huntington's disease in mice using healthy human brain cells. The findings, which were published today in the journal Nature Communications, could ultimately point to a new method to treat the disease.

7 Jun 2016

Researchers find link between obesity and disease relapse in pediatric Hodgkin lymphoma patients

Obesity has been identified as an adverse risk factor for survival in many adult and childhood cancers, but not in pediatric Hodgkin lymphoma, the most common cancer in adolescents.

7 Jun 2016

Nivolumab drug benefits metastatic RCC patients who continued treatment beyond progression

In a large randomized study, the immunotherapy drug nivolumab, a checkpoint inhibitor, was shown to be a safe and effective therapy for kidney cancer even in patients who continued treatment after their disease progressed.

7 Jun 2016

Two autologous stem-cell transplants improve survival of children with high-risk neuroblastoma

Children with high-risk neuroblastoma whose treatment included two autologous stem-cell transplants were more likely to be free of cancer three years later than patients who underwent a single transplant, a Phase 3 clinical trial has found.

7 Jun 2016

Scientists discover unexpected functions of snoRNAs that explains cause of some diseases

Scientists have discovered unexpected functions of small nucleolar RNAs (snoRNAs) that explain the cause of some diseases.

7 Jun 2016

Fit Families program helps combat childhood obesity in New Mexico

Battling the childhood obesity epidemic is a priority for many researchers, as obesity during adolescence increases the risk of chronic diseases throughout life. Because obese children have lower quality of life and self-esteem, greater levels of depression and anxiety, and also face more teasing and bullying than normal-weight peers, including mental health in any intervention is necessary.

7 Jun 2016

GFE3 protein may help researchers modify brain activity, memory in targeted ways

Scientists at USC have developed a new tool to modify brain activity and memory in targeted ways, without the help of any drugs or chemicals.

7 Jun 2016

Responsive parenting intervention helps curb childhood obesity

Mothers who practiced responsive parenting -- including reacting promptly and appropriately to hunger and fullness cues -- were less likely to have overweight babies at their one-year checkup than those who did not, say health researchers.

7 Jun 2016

RapifleX MALDI PharmaPlus Solution for uHTS launched by Bruker

At the 64th ASMS Conference, Bruker announces the launch of the new rapifleX™ MALDI PharmaPulse™ (MPP) solution. It is the latest addition to Bruker’s portfolio of innovative products designed to assist pharmaceutical, biotech and CRO customers to accelerate drug discovery, and rapifleX MPP can dramatically lower the cost of ultra-high throughput screening (uHTS) with further improved results.

From Bruker Daltonics 7 Jun 2016

Medical News

Maternal immune dysfunction linked to risk of autism with intellectual disability in children

Maternal topiramate use in conjunction with other anti-epileptic drugs may cause fetal malformations

Study challenges notion of fear of weight gain in patients with anorexia nervosa

Common angina drug can stimulate patient's own white blood cells to combat cryptococcosis

First European fully superconductive coil reaching a magnetic field of 25 Tesla produced

PREDIMED study weighs in to dietary fat discussion

Post-CABG hospital stays longer in severely obese patients

TAVI matches SAVR for early and midterm mortality

Cerebral microbleeds warn of dementia risk

Unsafe antiplatelet use persists in PCI patients

Subcutaneous treatment with cord blood stem cells improves eczema symptoms

Mice implanted with human glia cells exhibit reduced symptoms of Huntington's disease

Researchers find link between obesity and disease relapse in pediatric Hodgkin lymphoma patients

Nivolumab drug benefits metastatic RCC patients who continued treatment beyond progression

Two autologous stem-cell transplants improve survival of children with high-risk neuroblastoma

Scientists discover unexpected functions of snoRNAs that explains cause of some diseases

Fit Families program helps combat childhood obesity in New Mexico

GFE3 protein may help researchers modify brain activity, memory in targeted ways

Responsive parenting intervention helps curb childhood obesity

RapifleX MALDI PharmaPlus Solution for uHTS launched by Bruker

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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