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Study finds black-white disparities in preterm birth in Canada

Black women in Canada have substantially higher rates of premature births than white women, mirroring relative disparities in the United States, according to a study led by researchers at McGill University. The findings are based on new cohort data from the Canadian Live Birth, Infant Death and Stillbirth Database linked to the Canadian census data.

10 Nov 2015

Researchers find greater genetic diversity among cancer cells than anticipated

The most rigorous genetic sequencing ever carried out on a single tumor reveals far greater genetic diversity among cancer cells than anticipated. Researchers from the University of Chicago and the Beijing Institute of Genomics estimate that the tumor, about 3.5 centimeters in diameter, contained more than 100 million distinct mutations within the coding regions of its genes—thousands of times more than expected.

10 Nov 2015

New method may extend use of noninvasive prenatal testing to detect chromosomal abnormalities

Researchers at the University of California, San Diego School of Medicine developed a method to expand the types of chromosomal abnormalities that noninvasive prenatal testing (NIPT) can detect. The study, published November 9 by Proceedings of the National Academy of Sciences, uses a semiconductor sequencing platform to identify small chromosomal deletions or duplications, such as occur in Cri du Chat Syndrome and DiGeorge Syndrome, with a simple blood test from the expectant mother.

10 Nov 2015

Idera begins enrollment in IMO-8400 Phase 2 clinical trial for treatment of dermatomyositis

Idera Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company developing Toll-like receptor (TLR) and RNA therapeutics for patients with cancer and rare diseases, today announced that the company has commenced enrollment in a Phase 2 clinical trial of IMO-8400, an investigational TLR 7, 8 and 9 antagonist, in patients with dermatomyositis. Dermatomyositis is a rare and debilitating inflammatory muscle and skin disease associated with significant morbidity, decreased quality of life and an increased risk of premature death.

10 Nov 2015

People with high fitness levels in midlife have lower annual health care costs after age 65

People with high fitness levels in midlife have significantly lower annual health care costs after age 65 than people with low fitness in midlife, after adjusting for cardiovascular risk factors, according to a study published in the Journal of the American College of Cardiology.

10 Nov 2015

Possible reasons found for Alzheimer’s treatment failure

Agglutinated proteins in the brain, known as amyloid-β plaques, are a key characteristic of Alzheimer’s. One treatment option uses special antibodies to break down these plaques.

10 Nov 2015

Women need different treatment from men with addiction, says McMaster University-led study

Painkillers prescribed by doctors are the starting point for an opioid addiction for more than half of female methadone clinic patients, and they need different treatment from men with addiction, says a study led by McMaster University researchers.

10 Nov 2015

Protein sensor for proprioception found

Can you touch a finger to the tip of your nose with your eyes closed? Most of us can, thanks to a sense called proprioception, which tells us where our body parts are relative to each other and our environment. Not surprisingly, this sense is essential for normal movement and balance—walking, for instance.

10 Nov 2015

Group therapy helps improve healthy behavior in people with cardiovascular risk factors

Peer group support, in the form of group therapy, was found to help improve healthy behavior in people with cardiovascular risk factors, according to a study released today by Valentin Fuster, MD, PhD, Director of Mount Sinai Heart and Physician-in-Chief of The Mount Sinai Hospital. Mount Sinai Heart is ranked No. 7 in the nation by U.S. News & World Report in its 2015 "Best Hospitals" issue.

10 Nov 2015

HSS researchers help identify lupus patients at increased risk of problem pregnancies

For years doctors have been advising patients with lupus not to get pregnant. It was assumed that the likelihood of pregnancy complications was too high in this population. However, ongoing work by researchers at Hospital for Special Surgery is helping identify those lupus patients who are - and aren't - at increased risk of problem pregnancies.

10 Nov 2015

L-DOPA drug may delay or prevent age-related macular degeneration

A drug already used safely to treat Parkinson's disease, restless leg syndrome and other movement disorders also could delay or prevent the most common cause of blindness affecting more than 9 million older Americans - age-related macular degeneration (AMD).

10 Nov 2015

Isosorbide mononitrate does not increase HFpEF patients' daily activity level

Heart failure patients with preserved ejection fraction (HFpEF) -- where the heart becomes stiff and cannot relax or fill properly -- did not have increased exercise tolerance after taking isosorbide mononitrate, compared to a placebo, according to a study presented today at the American Heart Association's Scientific Sessions 2015.

10 Nov 2015

Self-weighing may have negative psychological outcomes for young women

Self-weighing can be a useful tool to help adults control their weight, but for adolescents and young adults this behavior may have negative psychological outcomes. Researchers from the University of Minnesota tracked the self-weighing behaviors of more than 1,900 young adults as part of Project EAT (Eating and Activity in Teens and Young Adults) and found increases in self-weighing to be significantly related to increases in weight concern and depression and decreases in body satisfaction and self-esteem among females.

10 Nov 2015

Sorafenib increases progression-free survival and disease control rate in NSCLC patients

Sorafenib, a tyrosine kinase inhibitor (TKI) targeting the receptors for vascular endothelial growth factor, platelet derived growth factor, and mast/stem cell growth factor, modestly increases progression-free survival (PFS), time to progression, and disease control rate in non-small cell lung cancer (NSCLC) patients who have relapsed or failed two or three previous treatment regimens.

10 Nov 2015

Disclosing genetic risk for CHD results in lower low-density lipoprotein cholesterol

A group of researchers led by Mayo Clinic has discovered that disclosing genetic risk for coronary heart disease (CHD) results in lower low-density lipoprotein cholesterol (LDL), also known as bad cholesterol. The findings of the Myocardial Infarction Genes (MI-GENES) Study were presented today at the annual American Heart Association Scientific Sessions 2015 as a late-breaking clinical trial.

10 Nov 2015

Researchers identify factors that spark formation of pluripotent cells

Researchers at EMBL's European Bioinformatics Institute and the Wellcome Trust- Medical Research Council Cambridge Stem Cell Institute at the University of Cambridge have identified factors that spark the formation of pluripotent cells.

10 Nov 2015

Thickness of the cortex in FFA can predict a person's ability to recognize faces and objects

When you see a familiar face, when a bird-watcher catches a glimpse of a rare bird perched on a limb, or when a car-fancier spots a classic auto driving past, the same small region in the brain becomes engaged.

10 Nov 2015

Ambulances deployed at temporary locations can reduce response time, save lives

Ambulances deployed at temporary locations that can be changed depending on the time of day and accident statistics can reduce response time and may save lives on the way to the hospital. Researchers at Sahlgrenska University studied fluid deployment of ambulances in Shiraz, Iran.

10 Nov 2015

Environmental factors may lead to development of some childhood cancers

Environmental factors may be a contributory cause in the development of some childhood cancers, leading scientists have revealed.

10 Nov 2015

Screening for asymptomatic atrial fibrillation could reduce risk of stroke, premature death

Screening for asymptomatic atrial fibrillation (AF) in people aged 65 and over and treating it with anticoagulant medications could greatly reduce the risk of stroke and premature death, say cardiologists in today's Journal of the American Medical Association.

10 Nov 2015

Medical News

Study finds black-white disparities in preterm birth in Canada

Researchers find greater genetic diversity among cancer cells than anticipated

New method may extend use of noninvasive prenatal testing to detect chromosomal abnormalities

Idera begins enrollment in IMO-8400 Phase 2 clinical trial for treatment of dermatomyositis

People with high fitness levels in midlife have lower annual health care costs after age 65

Possible reasons found for Alzheimer’s treatment failure

Women need different treatment from men with addiction, says McMaster University-led study

Protein sensor for proprioception found

Group therapy helps improve healthy behavior in people with cardiovascular risk factors

HSS researchers help identify lupus patients at increased risk of problem pregnancies

L-DOPA drug may delay or prevent age-related macular degeneration

Isosorbide mononitrate does not increase HFpEF patients' daily activity level

Self-weighing may have negative psychological outcomes for young women

Sorafenib increases progression-free survival and disease control rate in NSCLC patients

Disclosing genetic risk for CHD results in lower low-density lipoprotein cholesterol

Researchers identify factors that spark formation of pluripotent cells

Thickness of the cortex in FFA can predict a person's ability to recognize faces and objects

Ambulances deployed at temporary locations can reduce response time, save lives

Environmental factors may lead to development of some childhood cancers

Screening for asymptomatic atrial fibrillation could reduce risk of stroke, premature death

How real-time off-gas analysis improves fermentation process control

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AI-powered analytics and experimental validation

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