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Genetic mutations in deadly Ebola virus appear to block antibody-based treatments

Genetic mutations called "escape variants" in the deadly Ebola virus appear to block the ability of antibody-based treatments to ward off infection, according to a team of U.S. Army scientists and collaborators. Their findings, published online this week in the journal Cell Reports, have implications for the continued development of therapeutics to treat Ebola virus disease, which has claimed the lives of over 11,000 people in West Africa since last year.

14 Sep 2015

Uninsured, Medicaid stroke victims experience worse medical outcomes than patients with private insurance

Stroke victims who use Medicaid or are uninsured were more likely to die, stay hospitalized longer and have worse medical outcomes than patients with private insurance, a study by University of Florida Health researchers has found.

14 Sep 2015

Weaker physical fitness, higher body fat content linked to arterial stiffness in children

Arterial wall stiffness and reduced arterial dilation are the first signs of cardiovascular diseases that can be measured. The Physical Activity and Nutrition in Children Study (PANIC) carried out in the Institute of Biomedicine at the University of Eastern Finland shows that low levels of physical activity, weaker physical fitness and higher body fat content are linked to arterial stiffness already in 6-8 year-old children.

14 Sep 2015

New UCLA study finds novel approach that may help delay declines in health

Why do some people remain healthy into their 80s and beyond, while others age faster and suffer serious diseases decades earlier? New research led by UCLA life scientists may produce a new way to answer that question -- and an approach that could help delay declines in health.

14 Sep 2015

Researchers identify new epigenetic markers for colorectal cancer

Researchers at Nanjing University, China, found new epigenetic markers for colorectal cancer which may offer a new approach for treatment.

14 Sep 2015

New study reveals link between cardiorespiratory fitness, brain activation and executive function in older adults

The aging process is associated with declines in brain function, including memory and how fast our brain processes information, yet previous research has found that higher levels of cardiorespiratory fitness in older adults leads to better executive function in the brain, which helps with reasoning and problem solving. Higher cardiorespiratory fitness levels have also been found to increase brain volume in key brain regions.

14 Sep 2015

Surgeons participate in record-setting day of organ transplantation at Baylor University Medical Center

One week ago, surgical teams took part in a record-setting day of organ transplantation at Baylor University Medical Center at Dallas. Surgeons on the medical staff performed nine organ transplants on seven patients in one calendar day.

11 Sep 2015

HealthSouth to offer $300M aggregate principal amount of senior notes through private placement

HealthSouth Corporation today announced it intends to offer through a private placement, subject to market and other conditions, $300 million aggregate principal amount of senior notes due 2025.

11 Sep 2015

New technique could improve selectivity of cancer drugs, decrease unwanted side effects in future

A class of therapeutic drugs known as protein kinase inhibitors has in the past decade become a powerful weapon in the fight against various life-threatening diseases, including certain types of leukemia, lung cancer, kidney cancer and squamous cell cancer of the head and neck.

11 Sep 2015

ULURU signs definitive agreement to sell common stock to European investors

ULURU Inc., a specialty pharmaceutical company focused on the development of a portfolio of wound management and oral care products, today announced the signing of a definitive agreement to sell an aggregate of 4,079,539 shares of its common stock at a price per share of $0.38 to a group of European investors, which is expected to result in gross proceeds of $1,550,225.

11 Sep 2015

Online course offered in October on zoonotic disease

Recent outbreaks of plague, tularemia and increasing incidents of rabies exposure highlight the importance of zoonotic disease education for physicians and public health professionals.

11 Sep 2015

nCounterRNA:Protein pancancer immune profiling panel launched by NanoString

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced the commercial launch of the nCounter® RNA:Protein PanCancer Immune Profiling Panel

From NanoString Technologies 11 Sep 2015

Mirati to present data on tyrosine kinase inhibitor at ESMO 2015 European Cancer Congress

Mirati Therapeutics, Inc., an oncology company focusing on genetic and epigenetic drivers of cancer, today announced it will present data on its tyrosine kinase inhibitor, MGCD516, at the ESMO 2015 European Cancer Congress being held in Vienna, Austria from September 25-29, 2015.

11 Sep 2015

Aspen Dental opens new office in Richmond, Kentucky

A new Aspen Dental is opening in Richmond, Kentucky on Thursday, September 17. Located at 1072 Barnes Mill Road, the conveniently-located practice will provide dental services that range from dentures and preventive care to general dentistry and restoration.

11 Sep 2015

Aridis' AR-301 granted FDA Fast Track Designation for treatment of pneumonia caused by S. aureus

Aridis Pharmaceuticals, Inc., a biopharmaceutical company applying proprietary technologies to produce novel anti-infectives and immunotherapies for infectious diseases, announced today that the U.S. Food and Drug Administration granted Fast Track Designation to AR-301, the Company's fully human anti-Staphylococcal alpha-toxin IgG1 monoclonal antibody (mAb).

11 Sep 2015

A growing number of deaths attributed to avoidable risk factors

A wide range of avoidable risk factors to health – ranging from air pollution to poor diets to unsafe water – account for a growing number of deaths and a significant amount of disease burden, according to a new analysis of 79 risks in 188 countries.

11 Sep 2015

Penn Medicine researchers show that DNA editing errors can lead to cancer

Sometimes when the immune system makes small mistakes, the body amplifies its response in a big way: Editing errors in the DNA of developing T and B cells can cause blood cancers. Now, researchers from the Perelman School of Medicine, University of Pennsylvania have shown that when the enzyme key to cutting and pasting segments of DNA hits so-called "off-target" spots on a chromosome, the development of immune cells can lead to cancer in animal models.

11 Sep 2015

Simple vision test can be a valuable sideline tool for concussion detection in athletes

A timed vision test that involves rapidly reading numbers off of cards can be a valuable sideline tool for detecting whether a concussion occurred while playing sports, according to a meta-analysis and systematic review led by NYU Langone Medical Center concussion specialists.

11 Sep 2015

New collaboration may allow researchers to develop potential gene therapies for pediatric diseases

A new collaboration between Seattle Children's Research Institute and bluebird bio, Inc., a biotechnology company based in Cambridge, Mass. and Seattle, will allow researchers to develop potentially transformative gene therapies for severe genetic and rare pediatric diseases. The collaboration supports pediatric researchers in Seattle who will work with bluebird bio scientists and the company's gene editing technology to research potential cures for genetic pediatric diseases.

11 Sep 2015

Targeting exhausted immune cells may change prognosis for leukemia relapse patients after transplant

Targeting exhausted immune cells may change the prognosis for patients with acute myeloid leukemia (AML) relapse after a stem cell transplant, according to Penn State College of Medicine researchers.

11 Sep 2015

Medical News

Genetic mutations in deadly Ebola virus appear to block antibody-based treatments

Uninsured, Medicaid stroke victims experience worse medical outcomes than patients with private insurance

Weaker physical fitness, higher body fat content linked to arterial stiffness in children

New UCLA study finds novel approach that may help delay declines in health

Researchers identify new epigenetic markers for colorectal cancer

New study reveals link between cardiorespiratory fitness, brain activation and executive function in older adults

Surgeons participate in record-setting day of organ transplantation at Baylor University Medical Center

HealthSouth to offer $300M aggregate principal amount of senior notes through private placement

New technique could improve selectivity of cancer drugs, decrease unwanted side effects in future

ULURU signs definitive agreement to sell common stock to European investors

Online course offered in October on zoonotic disease

nCounterRNA:Protein pancancer immune profiling panel launched by NanoString

Mirati to present data on tyrosine kinase inhibitor at ESMO 2015 European Cancer Congress

Aspen Dental opens new office in Richmond, Kentucky

Aridis' AR-301 granted FDA Fast Track Designation for treatment of pneumonia caused by S. aureus

A growing number of deaths attributed to avoidable risk factors

Penn Medicine researchers show that DNA editing errors can lead to cancer

Simple vision test can be a valuable sideline tool for concussion detection in athletes

New collaboration may allow researchers to develop potential gene therapies for pediatric diseases

Targeting exhausted immune cells may change prognosis for leukemia relapse patients after transplant

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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