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Blood stem cell self-renewal dependent on surroundings

Stem cells have two important capabilities: they can develop into a wide range of cell types and simultaneously renew themselves, creating fresh stem cells. Using a model of the blood forming (hematopoietic) system, researchers at the Technical University of Munich (TUM) have now been able to precisely determine, which signaling pathways play an essential role in the self-renewal of blood stem cells. A particularly decisive role in this process is the interactive communication with surrounding tissue cells in the bone marrow.

3 Nov 2015

Approval to start trial of Videregen's replacement trachea technology

The INSPIRE consortium, led by Videregen Ltd, has received approval from the MHRA1 to start a UK clinical trial with its tissue engineered replacement trachea.

3 Nov 2015

Alnylam presents positive ongoing phase 2 open-label extension data for Patisiran and Revusiran

Alnylam Pharmaceuticals, Inc. has announced new results from its ongoing Phase 2 open-label extension (OLE) studies with patisiran and revusiran, investigational RNAi therapeutics targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR amyloidosis).

3 Nov 2015

Misleading symptoms confuse management of older patients with post-HSE relapse

Research shows that teenagers and adults with immune-mediated relapse after herpes simplex encephalitis rarely display the symptoms typically seen in children, delaying the initiation of vital immunotherapy.

3 Nov 2015

General psychiatric support warranted in MS patients

Multiple sclerosis has a nonspecific effect on psychiatric morbidity, increasing the risk of all psychiatric disorders, shows a large population-based study.

3 Nov 2015

Standing one-quarter of the day linked to reduced likelihood of obesity

Standing for at least one-quarter of the day has been linked to lower odds of obesity in a new study led by the American Cancer Society in collaboration with The Cooper Institute, the University of Texas, and the University of Georgia.

3 Nov 2015

Researchers explore effects of hypoglycemia on cardiovascular autonomic control

Past studies have shown an association between strict control of blood sugar and increased mortality. These studies have also suggested that a consequence of this strict control is low blood sugar (called hypoglycemia), which may have adverse effects on the heart.

3 Nov 2015

Researchers find strong associations between hunger and poor health

It may come as a surprise that, even after the Great Recession ended in 2009, almost 50 million people in the United States are food insecure -- that is, they lack access to adequate food because of limited money or other resources. University of Illinois economist Craig Gundersen and University of Kentucky's James Ziliak examined recent research on food insecurity and its association with poor health and offer suggestions, including that doctors screen for hunger.

3 Nov 2015

Lab experiment leads researchers to major red blood cell discovery

A bizarre result of a routine lab experiment has led researchers at the University of Virginia School of Medicine to an unexpected new way to trigger the production of red blood cells. This could represent a significant step forward in the battle against anemia, benefitting people with diabetes, people with kidney disease or cancer, and older people for whom anemia can become a chronic problem.

3 Nov 2015

Good news for patients suffering from dry age-related macular degeneration

Scientists have good news for patients who suffer from currently untreatable dry age-related macular degeneration (dry AMD). In a new study, researchers identified a potential target for future therapies to slow the progression of the blinding condition. Published in Investigative Ophthalmology & Visual Science, the findings indicate that treatments currently used for other conditions could also work for dry AMD.

3 Nov 2015

VUMC, UCSF investigators awarded $6 million NIH grant to develop implantable artificial kidney

The National Institutes of Health has awarded a four-year, $6 million grant to investigators at Vanderbilt University Medical Center and the University of California at San Francisco to develop an implantable artificial kidney.

3 Nov 2015

First scholarly medical journal launched by Marshall University School of Medicine

The Marshall University Joan C. Edwards School of Medicine has launched its first scholarly medical journal. The Marshall Journal of Medicine is a peer-reviewed, open-access online journal designed to shed light on medical issues and conditions of priority to West Virginians and the Appalachian region.

3 Nov 2015

Couples who share household work have satisfying sex life

Looking for more and better sex? If you're a man, you might consider doing the dishes once in a while. A new study out of the University of Alberta reveals that couples enjoyed more frequent and satisfying sex for both partners when men made a fair contribution to housework. The same study also found there's no relationship between the amount of housework male partners completed and the sexual functioning of a couple.

3 Nov 2015

APOE ε4 predicts risk of future depression

One of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).

3 Nov 2015

HIV, Ebola appear to be of animal origin

The hepatitis A virus can trigger acute liver inflammation which generally has a mild course in small children but which can become dangerous in adults.

3 Nov 2015

$Older people with age-related muscle loss face greater risk of falls, bone fractures$

Older people with age-related muscle loss face greater risk of falls, bone fractures

Older people with an age-related loss of muscle mass and strength may be at greater risk of falling and bone fractures, according to new research led by the University of Southampton.

3 Nov 2015

Deaths from avoidable risk factors: an interview with Dr Ali Mokdad, IHME

The study showed that about thirty percent to maybe half of the leading causes of death in the world are preventable. These are risk factors that you could manage and thus you could prevent a lot of premature deaths.

3 Nov 2015

Expert proposes new solution to current gridlock over regulation of dietary supplements

A former principal deputy commissioner of the U.S. Food and Drug Administration is proposing a solution to the current gridlock over the regulation of dietary supplements: Focus less on whether these vitamins, minerals and herbal extracts actually do what they claim and instead take important steps to improve their safety.

3 Nov 2015

Aprima selects Kno2 interoperability platform to meet attestation requirements under Meaningful Use Stage 2

Aprima Medical Software has selected the Kno2™ interoperability platform to enable its physician practices to easily and cost-effectively meet the requirements for electronic transmission of Transition of Care (TOC) documents mandated under Meaningful Use Stage 2.

3 Nov 2015

Federal food policy changes boost healthful food options at smaller urban corner stores

Federal food policy changes led to increased availability of healthy foods at smaller urban corner stores in Baltimore, new Johns Hopkins Bloomberg School of Public Health research suggests. Increases in healthy food were greatest in corner stores and in neighborhoods with a majority of black residents.

3 Nov 2015

Medical News

Blood stem cell self-renewal dependent on surroundings

Approval to start trial of Videregen's replacement trachea technology

Alnylam presents positive ongoing phase 2 open-label extension data for Patisiran and Revusiran

Misleading symptoms confuse management of older patients with post-HSE relapse

General psychiatric support warranted in MS patients

Standing one-quarter of the day linked to reduced likelihood of obesity

Researchers explore effects of hypoglycemia on cardiovascular autonomic control

Researchers find strong associations between hunger and poor health

Lab experiment leads researchers to major red blood cell discovery

Good news for patients suffering from dry age-related macular degeneration

VUMC, UCSF investigators awarded $6 million NIH grant to develop implantable artificial kidney

First scholarly medical journal launched by Marshall University School of Medicine

Couples who share household work have satisfying sex life

APOE ε4 predicts risk of future depression

HIV, Ebola appear to be of animal origin

Older people with age-related muscle loss face greater risk of falls, bone fractures

Deaths from avoidable risk factors: an interview with Dr Ali Mokdad, IHME

Expert proposes new solution to current gridlock over regulation of dietary supplements

Aprima selects Kno2 interoperability platform to meet attestation requirements under Meaningful Use Stage 2

Federal food policy changes boost healthful food options at smaller urban corner stores

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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