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Roche submits cobas EGFR v2 test PMA to FDA as companion diagnostic test for AZD9291

Roche today announced it has submitted the cobas EGFR Mutation Test v2 for Premarket Approval (PMA) to the U.S. Food and Drug Administration, as a companion diagnostic test for AZD9291, an AstraZeneca investigational therapy for non-small cell lung cancer patients with an acquired resistant mutation.

30 Jul 2015

Easter Seals’ board chairman climbs Mount Kilimanjaro to raise money for annual fundraiser

Rick Davidson, international board chairman for Easter Seals, the leading non-profit provider of services for individuals with autism, developmental disabilities, physical disabilities and other special needs, will make the complex and demanding climb and decent of Mount Kilimanjaro to raise money for Climb for Kids, a fundraiser for Easter Seals.

30 Jul 2015

IBM, CVS Health to transform care management services for patients with chronic disease

CVS Health (NYSE: CVS) and IBM today announced they will use predictive analytics and Watson cognitive computing to transform care management services for patients with chronic disease.

30 Jul 2015

More work needed to support consumers after enrolling in insurance plan under Affordable Care Act

Enrolling in an insurance plan under the Affordable Care Act is only the first step for consumers to be actively engaged in their health care, according to a new analysis from RAND Corporation researchers.

30 Jul 2015

Novel 3D human skin tissue model could help detect presence of known skin sensitizers in medical device extracts

New research shows that exposing a 3D human skin tissue model to extracts of medical device materials can detect the presence of sensitizers known to cause an allergic response on contact in some individuals. Conventional skin sensitization testing of medical devices relies on animal testing, whereas human skin models could replace animal methods, according to an article in the new journal Applied In Vitro Toxicology, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

30 Jul 2015

Study sheds light on certain antagonist drugs that block physiological responses

Members of the Consolidated Research Group of Molecular Neurobiology of the Department of Biochemistry and Molecular Biology of the University of Barcelona (UB), affiliated with the Centre for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), have published a study in the journal Proceedings of the National Academy of Sciences (PNAS) about the formation of G protein-coupled receptors (GPCRs) which allows understanding the unexpected behaviour of some antagonists that block physiological responses.

30 Jul 2015

New study suggests salt-tolerant vegetable seedlings for coastal area production

Crop production in coastal areas is threatened by seawater intrusion, which increases soil salinity. Excessive salinity in soil and irrigation water, in combination with waterlogging, can significantly affect the growth and quality for agricultural crops, especially those vegetables that are sensitive to salinity.

30 Jul 2015

Using physical processes to treat ships' ballast water can prevent spread of harmful organisms into local environment

Untreated ballast water discharge from ships can spread living organisms and even pathogens across the world thereby introducing non-native or invasive species into the local environment. Scientists at Helmholtz Zentrum München therefore recommend using physical treatment processes such as filtration rather than electrochemical disinfection, which creates countless potentially toxic compounds.

30 Jul 2015

Plants send out stress signals normally associated with animals

University of Adelaide research has shown for the first time that, despite not having a nervous system, plants use signals normally associated with animals when they encounter stress.

30 Jul 2015

Balancing cellular aging and cancer risk through biotechnology

In a way, trying to repair age-related heart damage and trying to fight cancer are opposite problems. Your heart cells' ability to regenerate themselves and proliferate into new, young cells degrades as you get older.

30 Jul 2015

Study reveals lingering effects of Superstorm Sandy among New Jersey residents

Superstorm Sandy continues to affect the lives of tens of thousands of New Jersey residents, in the form of unfinished repairs, disputed claims, and recurrent mold. These after-effects still linger for Sandy-impacted residents, and are associated with increased odds of residents experiencing mental health distress, post-traumatic stress disorder (PTSD), and depression.

30 Jul 2015

Researchers at Barrow Neurological Institute uncover brain surgery that changed history

Researchers at Barrow Neurological Institute have spent years of medical sleuthing across three continents to uncover a brain surgery that changed history.

30 Jul 2015

Intraoperative fluorescent imaging detects lung adenocarcinoma during pulmonary resection

More than 80,000 people undergo resection of a pulmonary tumor each year, and currently the only method to determine if the tumor is malignant is histologic analysis. A new study reports that a targeted molecular contrast agent can be used successfully to cause lung adenocarcinomas to fluoresce during pulmonary surgery.

30 Jul 2015

Research: Algae’s natural sunscreen molecules absorb UVA and UVB radiation with high efficiency

For consumers searching for just the right sunblock this summer, the options can be overwhelming. But scientists are now turning to the natural sunscreen of algae -- which is also found in fish slime -- to make a novel kind of shield against the sun's rays that could protect not only people, but also textiles and outdoor materials.

30 Jul 2015

Study on marine snails could help better understand underlying mechanisms of age-related memory loss

A new research study on marine snails uncovered the first cells in the nervous system to fail during aging. The University of Miami Rosenstiel School of Marine and Atmospheric Science researchers' findings are important to better understanding the underlying mechanisms of age-related memory loss in humans.

30 Jul 2015

New chemical reaction breaks strongest bond in molecules instead of weakest

Researchers at Princeton have developed a new chemical reaction that breaks the strongest bond in a molecule instead of the weakest, completely reversing the norm for reactions in which bonds are evenly split to form reactive intermediates.

30 Jul 2015

New national survey finds lack of COPD knowledge among patients

In a new national survey of chronic obstructive pulmonary disease (COPD) patients, Health Union reveals a surprising lack of awareness of risk factors and knowledge of diagnosis stage among patients. Results demonstrate a severe impact on quality of life, employment, and ability to afford treatment.

30 Jul 2015

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

New research from Uppsala University shows promising progress in the use of anti-inflammatory cytokine for treatment of type 1 diabetes. The study, published in the open access journal Scientific Reports (Nature Publishing Group), reveals that administration of interleukin-35 (a protein made by immune cells) to mice with type 1 diabetes, reverses or cures the disease by maintaining a normal blood glucose level and the immune tolerance.

30 Jul 2015

Commonly prescribed drug also lowers blood pressure when combined with diuretic

With the growth of electronic medical records, research utilizing data from a large number of patients, known as big data studies, can provide important information which may be unattainable via clinical trials which tend to be costly, time-consuming and involve fewer patients.

30 Jul 2015

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been unknown. Publishing online in Endocrinology, Buck Institute assistant research professor Akos Gerencser, PhD, shows that in patients with type 2 diabetes the balance between supply and demand of the mitochondrial membrane potential (ΔψM) is altered causing a decrease in the signaling that turns on insulin secretion.

30 Jul 2015

Medical News

Roche submits cobas EGFR v2 test PMA to FDA as companion diagnostic test for AZD9291

Easter Seals’ board chairman climbs Mount Kilimanjaro to raise money for annual fundraiser

IBM, CVS Health to transform care management services for patients with chronic disease

More work needed to support consumers after enrolling in insurance plan under Affordable Care Act

Novel 3D human skin tissue model could help detect presence of known skin sensitizers in medical device extracts

Study sheds light on certain antagonist drugs that block physiological responses

New study suggests salt-tolerant vegetable seedlings for coastal area production

Using physical processes to treat ships' ballast water can prevent spread of harmful organisms into local environment

Plants send out stress signals normally associated with animals

Balancing cellular aging and cancer risk through biotechnology

Study reveals lingering effects of Superstorm Sandy among New Jersey residents

Researchers at Barrow Neurological Institute uncover brain surgery that changed history

Intraoperative fluorescent imaging detects lung adenocarcinoma during pulmonary resection

Research: Algae’s natural sunscreen molecules absorb UVA and UVB radiation with high efficiency

Study on marine snails could help better understand underlying mechanisms of age-related memory loss

New chemical reaction breaks strongest bond in molecules instead of weakest

New national survey finds lack of COPD knowledge among patients

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

Commonly prescribed drug also lowers blood pressure when combined with diuretic

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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