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NEB releases new NEBNext Ultra II DNA Library Prep Kit

New England Biolabs today announced the release of the NEBNext Ultra II DNA Library Prep Kit for Illumina next generation sequencing systems. The new Ultra II kit substantially improves upon its predecessor to produce libraries of both higher quality and higher yield from a variety of sample types, including challenging ones, such as formalin-fixed, paraffin-embedded (FFPE) samples and those containing low amounts of input DNA.

From New England Biolabs 16 Oct 2015

Bolton Medical reports first commercial implant of TREO Abdominal Stent-Graft System

Bolton Medical, a subsidiary of the WerfenLife Company, announced the first commercial implant of the TREO Abdominal Stent-Graft System by Professor Giovanni Torsello, MD, Director of the Center for Vascular and Endovascular Surgery at St. Franciscus Hospital Muenster in Munster, Germany.

16 Oct 2015

Boehringer Ingelheim announces FDA approval of Praxbind (idarucizumab)

Boehringer Ingelheim Pharmaceuticals, Inc. today announced the U.S. Food and Drug Administration granted approval of Praxbind (idarucizumab). PRAXBIND is indicated for patients treated with Pradaxa (dabigatran etexilate mesylate), when reversal of the anticoagulant effects of dabigatran is needed for emergency surgery/urgent procedures or in life-threatening or uncontrolled bleeding.

16 Oct 2015

Antibiotic resistance potentially threatens the safety and efficacy of surgical procedures and immunosuppression therapies

This week The Lancet Infectious Diseases journal published the strongest evidence to date that increasing antibiotic resistance could have disastrous consequences for patients undergoing surgery or cancer chemotherapy. Based on a review of published literature, researchers predict that a 30% reduction in the efficacy of the prophylactic antibiotics routinely given when these procedures are performed could result in 120,000 more infections and 6300 infection-related deaths every year in the USA alone.

16 Oct 2015

Glutamate imaging may guide surgery in ‘nonlesional’ epilepsy

Glutamate imaging may be capable of identifying the focus of epileptic seizures in patients who appear to have nonlesional epilepsy on standard imaging techniques, researchers report in Science Translational Medicine.

16 Oct 2015

Seizure control improves for TSC patients undergoing more extensive surgery

Children with the genetic disorder tuberous sclerosis complex (TSC) often need epilepsy surgery for severe, uncontrollable seizures. A new study finds that seizure control is improved for patients undergoing more extensive surgery, reports the October issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

16 Oct 2015

Loyola gastroenterologist provides tips to IBS patients for healthy living

More than 20 percent of the US population lives with irritable bowel syndrome (IBS) and for many Americans it is an ongoing challenge. But when it comes to treatment, old advice from Mom was right. Often, the key is to eat right and go outside and play.

16 Oct 2015

Study: Young Latinos in rural areas face discrimination when obtaining health care services

Young Latinos living in rural areas say they face discrimination when they obtain health care services - a factor that could contribute to disparities in their rates for obtaining medical care and in their health outcomes, a new study from Oregon State University has found.

16 Oct 2015

Brown University researchers describe new method to test HIV mutations

Tests that can distinguish whether HIV-positive people are infected with a drug-resistant strain or a non-resistant strain allow patients to get the most effective treatment as quickly as possible. In the November edition of the Journal of Molecular Diagnostics, a team of Brown University researchers describes a new method that works faster and more sensitively in lab testing than the current standard technologies.

16 Oct 2015

UM SOM researchers to initiate first clinical trial of GammaPod system in patients with early-stage breast cancer

After more than a decade of research and development, researchers in the Department of Radiation Oncology at the University of Maryland School of Medicine will begin enrolling patients in the first clinical trial of GammaPod, a new high-precision, image-guided radiation therapy system specifically designed to treat early-stage breast cancer.

16 Oct 2015

Hiroshima University researchers demonstrate how Sendai virus escapes host immune system

A research group at Hiroshima University demonstrated the mechanism by which the Sendai virus (SeV) escapes the host immune system. The researchers examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal transduction pathway of interferon gamma.

16 Oct 2015

Aratana announces $40 million senior secured credit facility

Aratana Therapeutics, Inc., a pet therapeutics company focused on the licensing, development and commercialization of innovative biopharmaceutical products for companion animals, today announced a $40 million senior secured credit facility with Pacific Western Bank, as agent and lender, and Oxford Finance LLC, as lender. The facility refinances the $15 million loan facility previously provided to the Company by Pacific Western Bank (as successor-in-interest to Square 1 Bank).

16 Oct 2015

Study reveals gene mutation that increases risk of SUDEP in patients with mild forms of disease

Researchers in the Adult Genetic Epilepsy Program of the Krembil Neuroscience Centre have discovered a gene mutation that increases the risk of sudden unexpected death in epilepsy (SUDEP) in patients with mild forms of the disease.

16 Oct 2015

WSU scientist wins federal grant to explore metabolism pathways, tobacco carcinogens

A Washington State University researcher has received a $2.6 million federal grant to study the body's ability to keep tobacco smoke components from causing cancer.

16 Oct 2015

Analysis of high-throughput sequencing data reveals new genes linked to chronic lymphocytic leukemia

Johannes Reiter, former PhD student in the group of Krishnendu Chatterjee at the Institute of Science and Technology Austria (IST Austria), is co-author of a Nature paper on genetic alterations that drive the progression and relapse of cancer.

16 Oct 2015

New breakthrough advances our understanding of how brain detects, prevents dehydration

Scientists at the Research Institute of the McGill University Health Centre (RI-MUHC) and Duke University have made a breakthrough that advances our understanding of how the brain detects and prevents dehydration.

16 Oct 2015

NIH's BCERP launches Columbia Mailman School & Columbia University Medical Center site

Columbia University's Mailman School of Public Health and Columbia University Medical Center together are one of six new sites being launched by the National Institutes of Health's Breast Cancer and Environment Research Program (BCERP).

16 Oct 2015

Rare genetic mutation could improve outcomes in NSCLC patients with brain metastases

Most patients with non-small cell lung cancer (NSCLC) that has metastasized to the brain have a dire prognosis. But Yale researchers have identified a subset of those patients with a rare genetic mutation who are living significantly longer than patients without the mutation.

16 Oct 2015

Study shows vitamin D, calcium supplements fail to protect against colorectal cancer

A large, randomized study at 11 U.S. hospitals including Dartmouth-Hitchcock Medical Center found that vitamin D and calcium supplements fail to protect against developing colorectal cancer.

16 Oct 2015

Two-Level IDE approval granted to Simplify Medical’s cervical artificial disc

Simplify Medical, Inc. is pioneering disc arthroplasty with the non-metal, MRI compatible Simplify™ Disc, a cervical artificial disc.

16 Oct 2015

Medical News

NEB releases new NEBNext Ultra II DNA Library Prep Kit

Bolton Medical reports first commercial implant of TREO Abdominal Stent-Graft System

Boehringer Ingelheim announces FDA approval of Praxbind (idarucizumab)

Antibiotic resistance potentially threatens the safety and efficacy of surgical procedures and immunosuppression therapies

Glutamate imaging may guide surgery in ‘nonlesional’ epilepsy

Seizure control improves for TSC patients undergoing more extensive surgery

Loyola gastroenterologist provides tips to IBS patients for healthy living

Study: Young Latinos in rural areas face discrimination when obtaining health care services

Brown University researchers describe new method to test HIV mutations

UM SOM researchers to initiate first clinical trial of GammaPod system in patients with early-stage breast cancer

Hiroshima University researchers demonstrate how Sendai virus escapes host immune system

Aratana announces $40 million senior secured credit facility

Study reveals gene mutation that increases risk of SUDEP in patients with mild forms of disease

WSU scientist wins federal grant to explore metabolism pathways, tobacco carcinogens

Analysis of high-throughput sequencing data reveals new genes linked to chronic lymphocytic leukemia

New breakthrough advances our understanding of how brain detects, prevents dehydration

NIH's BCERP launches Columbia Mailman School & Columbia University Medical Center site

Rare genetic mutation could improve outcomes in NSCLC patients with brain metastases

Study shows vitamin D, calcium supplements fail to protect against colorectal cancer

Two-Level IDE approval granted to Simplify Medical’s cervical artificial disc

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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