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Amphetamine-based drug Evekeo effective in treating ADHD symptoms in children

The amphetamine-based drug Evekeo, given once or twice daily to children 6-12 years of age, is effective in treating attention-deficit/hyperactivity disorder (ADHD) symptoms and improving performance in a laboratory classroom setting, according to the results of a new study published in the Journal of Child and Adolescent Psychopharmacology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

30 Jun 2015

Kay E. Davies named recipient of ASHG's 2015 William Allan Award

The American Society of Human Genetics has named Kay E. Davies, DPhil, Dr. Lee's professor of anatomy, associate head of the medical sciences division; and director of the Medical Research Council Functional Genomics Unit in the department of physiology, anatomy and genetics at the University of Oxford, the 2015 recipient of the annual William Allan Award.

30 Jun 2015

Athletes need to drink when thirsty to avoid exercise-associated hyponatremia

For hikers, football players, endurance athletes, and a growing range of elite and recreational exercisers, the best approach to preventing potentially serious reductions in blood sodium level is to drink when thirsty, according to an updated consensus statement on exercise-associated hyponatremia (EAH).

30 Jun 2015

$FDA accepts TxCell’s IND application for Ovasave for treatment of refractory Crohn’s disease$

FDA accepts TxCell’s IND application for Ovasave for treatment of refractory Crohn’s disease

TxCell SA, a biotechnology company developing innovative, personalized T cell immunotherapies using antigen specific regulatory T-cells for severe chronic inflammatory and autoimmune diseases, announces today that the United States Food and Drug Administration has accepted TxCell’s Investigational New Drug application for the company’s lead product, Ovasave(R), currently in a phase 2b clinical trial for the treatment of patients with refractory Crohn’s disease.

30 Jun 2015

Survey provides estimates of wide range of violence against children, youth

More than a third of children and teens 17 and younger experienced a physical assault in the last year, primarily at the hands of siblings and peers, according to an article published online by JAMA Pediatrics.

30 Jun 2015

Residents’ participation does not increase patients’ risks of postoperative complications after brain and spine surgeries

An analysis of the results of more than 16,000 brain and spine surgeries suggests patients have nothing to fear from having residents — physicians-in-training — assist in those operations.

30 Jun 2015

Neighborhood physical and social environments may affect type 2 diabetes risk

Neighborhood resources to support greater physical activity and, to a lesser extent, healthy diets appear to be associated with a lower incidence of type 2 diabetes, although the results vary by the method of measurement used, according to an article published online by JAMA Internal Medicine.

30 Jun 2015

Study may lead to better treatments for children with neuroblastoma

Researchers studying the pediatric cancer neuroblastoma have detailed how cancer-driving mutations evolve during chemotherapy, and they hope to exploit this knowledge to design better treatments for children.

30 Jun 2015

Rare genetic variants in A2ML1 gene responsible for chronic middle ear infections, say researchers

Many parents have heard the night-time cry of "my ear hurts." For some children, this might happen frequently beginning in infancy and even persist into adulthood. An international consortium led by those at Baylor College of Medicine may have taken the first step on the road to understanding why only some people get frequent painful or chronic middle ear infections. The culprit may be rare genetic variants in a gene called A2ML1.

30 Jun 2015

Danish scientists discover what controls ADAM17 enzyme that aids growth of cancer tumours

Researchers from the University of Copenhagen have discovered what regulates an enzyme that is central to the growth of cancer tumours. This could be of great value to future cancer treatment.

30 Jun 2015

TSRI-led study identifies new immune molecules that protect against Marburg virus

A new study led by scientists at The Scripps Research Institute identifies new immune molecules that protect against deadly Marburg virus, a relative of Ebola virus. The research provides ingredients needed to develop treatments for future Marburg outbreaks.

30 Jun 2015

Researchers discover gene locations affecting wrist bones in children

Pediatric researchers have discovered gene locations affecting bone strength in wrist bones, the most common site for fractures in children. Children who have those genetic variants may be at higher-than-average risk of wrist fractures, and could especially benefit from activities and diets that promote bone strength.

30 Jun 2015

PharmaMar begins PM1183 phase III study in patients with platinum-resistant ovarian cancer

PharmaMar announced today the start of a phase III study for the anticancer agent PM1183 in patients with platinum-resistant ovarian cancer (PROC). Once study objectives are met, the CORAIL trial (NCT02421588) will be used to support the regulatory filing of PM1183 as treatment for this indication.

30 Jun 2015

Tiny aquatic flatworms could replace existing animal models used in neurotoxicity tests

Laboratories that test chemicals for neurological toxicity could reduce their use of laboratory mice and rats by replacing these animal models with tiny aquatic flatworms known as freshwater planarians.

29 Jun 2015

New technology can detect illegal drugs from a single fingerprint

An innovative technology pioneered by Sheffield Hallam University academics can detect the presence of a range of illegal and designer drugs from a single fingerprint, which could be a valuable new tool in bringing drug dealers and other criminals to justice.

From Sheffield Hallam University 29 Jun 2015

Fraser Communications wins another 3-year contract for First 5 California campaigns

Fraser Communications, which has designed award-winning campaigns the past six years for First 5 California, won another 3-year contract with the government organization to promote child brain development, early literacy, healthy nutrition, and other critical information for parents of young children.

29 Jun 2015

Inhibikase Therapeutics receives Phase II SBIR grant to advance novel RAMP medicinal chemistry program

Inhibikase Therapeutics, Inc. announces the receipt of a Phase II SBIR grant in the amount of $1.54 million dollars from the U.S. National Institutes of Health to advance its novel Re-engineering with Metabolism Preserved (RAMP) medicinal chemistry program.

29 Jun 2015

Researchers discover mechanism that regulates metabolism

The protein complex mTORC1 is a central regulator of cell metabolism. In the active state, it stimulates anabolic processes and increases the production and storage of proteins and lipids. Researchers from the German Leibniz Institute for Age Research in Jena and the Dutch Ageing Institute ERIBA in Groningen discovered a mechanism how mTORC1 regulates metabolism: It controls the expression of a specific variant of the transcriptional regulator C/EBPβ.

29 Jun 2015

Flex reveals employers' current usage and future impact of ACA

Today, Flexible Benefit Service Corporation, a leading benefits administrator publicly released its first FSA, HSA & HRA Report: Trends & Predictions. The report, which was based on a nationwide survey on these Consumer-Driven Accounts, reveals employers' current usage and future impacts as the Affordable Care Act continues to be implemented and market conditions change.

29 Jun 2015

Clinical data demonstrates safe administration of Pexa-Vec in patients with metastatic colorectal cancer

SillaJen, Inc., a private clinical-stage biotherapeutics company focused on the development of oncolytic immunotherapy products for cancer, today announced a publication of data demonstrating that in a Phase Ib trial of Pexa-Vec, patients received multiple bi-weekly doses of its lead product Pexa-Vec, representing the first report of multiple intravenous administrations of an oncolytic vaccinia.

29 Jun 2015

Medical News

Amphetamine-based drug Evekeo effective in treating ADHD symptoms in children

Kay E. Davies named recipient of ASHG's 2015 William Allan Award

Athletes need to drink when thirsty to avoid exercise-associated hyponatremia

FDA accepts TxCell’s IND application for Ovasave for treatment of refractory Crohn’s disease

Survey provides estimates of wide range of violence against children, youth

Residents’ participation does not increase patients’ risks of postoperative complications after brain and spine surgeries

Neighborhood physical and social environments may affect type 2 diabetes risk

Study may lead to better treatments for children with neuroblastoma

Rare genetic variants in A2ML1 gene responsible for chronic middle ear infections, say researchers

Danish scientists discover what controls ADAM17 enzyme that aids growth of cancer tumours

TSRI-led study identifies new immune molecules that protect against Marburg virus

Researchers discover gene locations affecting wrist bones in children

PharmaMar begins PM1183 phase III study in patients with platinum-resistant ovarian cancer

Tiny aquatic flatworms could replace existing animal models used in neurotoxicity tests

New technology can detect illegal drugs from a single fingerprint

Fraser Communications wins another 3-year contract for First 5 California campaigns

Inhibikase Therapeutics receives Phase II SBIR grant to advance novel RAMP medicinal chemistry program

Researchers discover mechanism that regulates metabolism

Flex reveals employers' current usage and future impact of ACA

Clinical data demonstrates safe administration of Pexa-Vec in patients with metastatic colorectal cancer

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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