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Amgen and Merck expand collaboration for Talimogene laherparepvec-KEYTRUDA combination study

Amgen and Merck, known as MSD outside the U.S. and Canada, today announced an expanded collaboration to evaluate the efficacy and safety of talimogene laherparepvec, Amgen's investigational oncolytic immunotherapy, in combination with KEYTRUDA® (pembrolizumab), Merck's anti-PD-1 therapy, in a Phase 1, open-label trial of patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN).

1 Jun 2015

Research shows HEOR data can be used to better determine value-based reimbursement strategies

Later this week, Cardinal Health Specialty Solutions will present a new series of health economic outcomes research (HEOR) studies that reinforce the importance of evaluating real-world treatment patterns when developing value-based reimbursement strategies.

1 Jun 2015

New clinical studies on Myriad Genetics myChoice HRD companion diagnostic test presented at ASCO 2015

Myriad Genetics, Inc. today announced new clinical studies on its myChoice HRD companion diagnostic test at the 2015 American Society of Clinical Oncology annual meeting being held in Chicago, Ill.

1 Jun 2015

ClinGen: New clinical genome resource may help understand clinical implications of genetic variants

Tremendous advances have been made in decoding the human genome in recent years but critical questions remain regarding what these variants mean and how they can be applied in clinical practice.

1 Jun 2015

U-M Food Allergy Center honors Mary Weiser's advocacy with renaming of center

Mary H. Weiser has watched in terror as her child was gripped by a severe allergic reaction after she ingested a simple food that most of us eat on a daily basis.

1 Jun 2015

Novartis to highlight strength of its expanded oncology portfolio at ASCO 2015

Novartis will highlight the strength of its expanded oncology portfolio in 21 medicines and 11 investigational compounds across more than 185 data presentations at the upcoming American Society of Clinical Oncology (ASCO) Annual Meeting, May 29-June 2, and the Congress of the European Hematology Association (EHA), June 11-14.

1 Jun 2015

Pharmacyclics initiates ibrutinib-MEDI4736 combination multi-center study for R/R DLBCL or FL

Pharmacyclics, Inc. today announced the initiation of PCYC-1136-CA, a multi-center study that will investigate the use of ibrutinib (IMBRUVICA®) in combination with MEDI4736, an investigational anti-PD-L1 immune checkpoint inhibitor being developed by AstraZeneca.

1 Jun 2015

Precision medicine helps improve patient health and reduces risk of side effects, says Penn Medical School dean

The rapidly emerging field of precision medicine is a "disruptive innovation" that offers the possibility of remarkably fine-tuned remedies to improve patient health while minimizing the risk of harmful side effects, says J. Larry Jameson, MD, PhD, dean of the Perelman School of Medicine and executive vice president of the University of Pennsylvania for the Health System, in this week's issue of the New England Journal of Medicine.

1 Jun 2015

Modified cold sore (herpes) virus improves survival in stage IIIb to IV melanoma patients

It's a new weapon in the arsenal of cancer fighting treatments: utilizing genetically modified viruses to invade cancer cells and destroy them from the inside.

1 Jun 2015

New data indicates that most microbes behave similarly on Earth and International Space Station

Do microbes grow differently on the International Space Station than they do on Earth? Results from the growth of microbes collected by citizen scientists in Project MERCCURI indicate that most behave similarly in both places.

1 Jun 2015

Vascular surgeries provide relief from two debilitating conditions

When Carol Werkman first saw Loyola University Medical Center vascular surgeon Bernadette Aulivola, MD, she was suffering from two debilitating conditions: Every time she ate, Mrs. Werkman felt terrible abdominal pain. And whenever she walked more than a few hundred feet, her legs would begin to hurt.

1 Jun 2015

Updated data from PROCLAIM national patient registry presented at 51st ASCO

Prometheus Laboratories, Inc. announced today the presentation of updated data from the PROCLAIM national patient registry in which first-line Proleukin® (aldesleukin for injection) therapy improved survival in patients with metastatic renal cell carcinoma (mRCC), compared to patients previously treated with targeted therapies.

1 Jun 2015

'Conflict of Interest and Scientific Discovery' symposium to be held at Penn’s Perelman School of Medicine

How can academic medical centers best manage the emerging issue of conflict of interest among scientists and physicians working to develop the next generation of treatments and cures? How do academic conflict of interest policies affect the process of scientific discovery?

1 Jun 2015

Norwegian Biotechnology Council recommends that egg donation be made legal in Norway

More than 5 million children in Europe have been born as a result of assisted reproductive technologies, yet many European countries, including Norway, have regulations that restrict different aspects of these technologies.

1 Jun 2015

UN's Global Road Safety Week aims at making roads safer

From 4 to 10 May, the world will be celebrating the UN's Global Road Safety Week under the theme 'Children and road safety', which follows a 10-year series of resolutions aimed at making roads safer.

1 Jun 2015

New study highlights the benefits of using sandwich system in organic apple orchards

In organic apple orchards, one of the most serious challenges for growers is determining ways to limit weed competition while improving soil quality and ensuring high yields of quality apples.

1 Jun 2015

Study shows antibiotic prescriptions in telemedicine exams are as frequent as regular exams

Patients treated for an acute respiratory infection by a doctor on a telephone or live video are as likely to be prescribed an antibiotic as patients who are treated by a physician face-to-face for the same illness, according to a new RAND Corporation study.

1 Jun 2015

Category 1 findings support robust abuse-deterrent features of Egalet-002 for management of severe pain

Egalet Corporation, a fully integrated specialty pharmaceutical company focused on developing, manufacturing and marketing innovative pain treatments, today announced positive top-line results from Category 1 abuse-deterrent studies for Egalet-002, an abuse-deterrent, extended-release, oral oxycodone-based product in development for the management of pain severe enough to require daily, around-the-clock opioid treatment and for which alternative treatments are inadequate.

1 Jun 2015

Strategies needed to optimize communications between police and ED workers

A good working relationship with police is essential for the smooth operation of a busy Emergency Department. Police are in and out of EDs regularly, supporting EMS, transporting patients and helping to provide a safe environment for hospital staff.

1 Jun 2015

New way to evaluate brainstorms in newborn very premature infants

Giant strides have been taken in the early care of very premature infants in postnatal intensive care units during the past two decades. Doctors can now support the function of especially the lungs, heart and the circulatory system so as to guarantee the survival of most of even extremely premature infants.

1 Jun 2015

Medical News

Amgen and Merck expand collaboration for Talimogene laherparepvec-KEYTRUDA combination study

Research shows HEOR data can be used to better determine value-based reimbursement strategies

New clinical studies on Myriad Genetics myChoice HRD companion diagnostic test presented at ASCO 2015

ClinGen: New clinical genome resource may help understand clinical implications of genetic variants

U-M Food Allergy Center honors Mary Weiser's advocacy with renaming of center

Novartis to highlight strength of its expanded oncology portfolio at ASCO 2015

Pharmacyclics initiates ibrutinib-MEDI4736 combination multi-center study for R/R DLBCL or FL

Precision medicine helps improve patient health and reduces risk of side effects, says Penn Medical School dean

Modified cold sore (herpes) virus improves survival in stage IIIb to IV melanoma patients

New data indicates that most microbes behave similarly on Earth and International Space Station

Vascular surgeries provide relief from two debilitating conditions

Updated data from PROCLAIM national patient registry presented at 51st ASCO

'Conflict of Interest and Scientific Discovery' symposium to be held at Penn’s Perelman School of Medicine

Norwegian Biotechnology Council recommends that egg donation be made legal in Norway

UN's Global Road Safety Week aims at making roads safer

New study highlights the benefits of using sandwich system in organic apple orchards

Study shows antibiotic prescriptions in telemedicine exams are as frequent as regular exams

Category 1 findings support robust abuse-deterrent features of Egalet-002 for management of severe pain

Strategies needed to optimize communications between police and ED workers

New way to evaluate brainstorms in newborn very premature infants

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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