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Gene responsible for cancer growth plays unexpected role in prostate cancer

A gene that is responsible for cancer growth plays a totally unexpected role in prostate cancer. The gene Stat3 is controlled by the immune modulator interleukin 6 and normally supports the growth of cancer cells. The international research team led by Prof. Lukas Kenner from the Medical University of Vienna, the Veterinary University of Vienna, and the Ludwig Boltzmann Institiute for Cancer Research (LBI-CR) discovered a missing link for an essential role of Stat3 and IL-6 signalling in prostate cancer progression.

22 Jul 2015

New TCR therapy demonstrates encouraging clinical responses in patients with multiple myeloma

Results from a clinical trial investigating a new T cell receptor (TCR) therapy that uses a person's own immune system to recognize and destroy cancer cells demonstrated a clinical response in 80 percent of multiple myeloma patients with advanced disease after undergoing autologous stem cell transplants (ASCT).

22 Jul 2015

Multi-year project aims to develop, improve clinical research tools for studying ASD

Government, non-profit, and other private partners will fund a multi-year project to develop and improve clinical research tools for studying autism spectrum disorder (ASD). The project will receive a total of $28 million over the next four years to test and refine clinical measures of social impairment in ASD in order to better evaluate potential behavioral and drug therapies.

22 Jul 2015

Study shows regions of genome underlying IBD consistent around the world

The first genetic study of inflammatory bowel disease (IBD) to include individuals from diverse populations has shown that the regions of the genome underlying the disease are consistent around the world. This study, conducted under the auspices of the International IBD Genetics Consortium, included nearly 10,000 DNA samples from people of East Asian, Indian or Iranian descent and an existing set of 86,640 samples drawn from across Europe, North America and Oceania.

22 Jul 2015

EGPAF calls for prioritizing HIV treatment among children

As the HIV/AIDS community gathers for the International AIDS Society Conference in Vancouver, Canada, the Elizabeth Glaser Pediatric AIDS Foundation joins the Vancouver Consensus in calling for universal treatment for all people living with HIV, regardless of CD4 count. Providing treatment for everyone living with HIV will be a paradigm shift in HIV treatment and prevention efforts, particularly for children living with HIV, and will save millions of lives.

22 Jul 2015

Dairy products could make probiotics more effective

The success of probiotics for boosting human health may depend partly upon the food, beverage, or other material carrying the probiotics, according to research published on July 10th in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.

22 Jul 2015

New research examines why some gaming habits escalating among adolescents

Technological innovations, multiple genres, online gaming and mobile apps have led gaming to become big business. Call of Duty Black Ops sold 1.4 million copies and registered 2.6 million Xbox Live players on launch day. Adolescents increasingly use gaming for a significant part of their leisure time.

22 Jul 2015

Heidelberg University scientists gain new insight into cytotoxic effect of Ebola virus

In the course of basic research in membrane biochemistry scientists at Heidelberg University have gained new insight into the cytotoxic effect of the Ebola virus. Employing biochemical and cell biological methods they have shed light on the molecular relationships between the Ebola glycoprotein and its role in mediating cytotoxicity.

22 Jul 2015

Study shows glitazone antidiabetic drug may reduce risk of Parkinson’s disease

A type of drug used to treat diabetes may reduce the risk of developing Parkinson’s disease, according to a new study published in PLOS Medicine.

22 Jul 2015

KalVista raises $33 million in Series B financing to support development of plasma kallikrein inhibitors

KalVista Pharmaceuticals, a research-led pharmaceutical company, today announced it has raised $33 million in a Series B financing to support its research and clinical development programs. KalVista will use the funds to advance its proprietary portfolio of plasma kallikrein inhibitors for treating diabetic macular edema (DME) and hereditary angioedema (HAE).

22 Jul 2015

Researchers report new drug combination that effectively treats HCV patients co-infected with HIV

Roughly 20 to 30 percent of patients with hepatitis C virus (HCV) are also infected with human immunodeficiency virus type 1 (HIV). Both blood-borne viruses share the same modes of transmission, but many HCV medications currently have significant limitations due to adverse interactions with HIV treatments. Researchers at University of California, San Diego School of Medicine report a new combination that effectively treats HCV in patients co-infected with HIV.

22 Jul 2015

Unique collaboration aims to transform geriatric care in North Texas

UNT Health Science Center will team up with JPS Health Network, Texas Christian University and the United Way's Area Agency on Aging of Tarrant County to transform geriatric care in North Texas by improving medical training and health-care delivery for the region's rapidly growing population of older residents.

22 Jul 2015

UCLA's Jonsson Comprehensive Cancer Center named among top 10 cancer centers in nation

UCLA's Jonsson Comprehensive Cancer Center is ranked among the top 10 cancer centers in the nation, according to a U.S. News & World Report survey of board-certified physicians from across the country. The survey reviewed patient outcomes, the cancer center's reputation among physicians, mortality rates and other care-related factors.

22 Jul 2015

Tyrone Regional Health Network signs letter of intent to become member of Penn State Health

Tyrone Regional Health Network and Penn State Health have signed a letter of intent to enter into formal affiliation. With approval by organizational boards and state authorities, Tyrone Regional will become a member of Penn State Health.

22 Jul 2015

Research suggests that only one in three older Americans have diabetes under control

Only one in three older Americans have their diabetes under control as measured by guidelines set by the American Diabetes Association, new Johns Hopkins Bloomberg School of Public Health research suggests.

22 Jul 2015

Study examines link between use of diabetes drug pioglitazone and increased risk of bladder cancer

Although some previous studies have suggested an increased risk of bladder cancer with use of the diabetes drug pioglitazone, analyses that included nearly 200,000 patients found no statistically significant increased risk, however a small increased risk could not be excluded, according to a study in the July 21 issue of JAMA.

22 Jul 2015

Use of dicloxacillin linked to INR decrease in patients taking vitamin K antagonists

Researchers have found an association between treatment with the antibiotic dicloxacillin and a decrease in international normalized ratio (INR; a measure of blood coagulation) levels among patients taking the vitamin K antagonists warfarin or phenprocoumon, according to a study in the July 21 issue of JAMA.

22 Jul 2015

AS03 and MF59 adjuvants increase immune responses to two doses of H7N9 influenza vaccine

In a phase 2 trial that included nearly 1,000 adults, the AS03 and MF59 adjuvants (a component that improves immune response of inactivated influenza vaccines) increased the immune responses to two doses of an inactivated H7N9 influenza vaccine, with AS03-adjuvanted formulations inducing the highest amount of antibody response, according to a study in the July 21 issue of JAMA.

22 Jul 2015

UCLA Health's hospitals named among nation's best in U.S. News and World Report

UCLA Health's hospitals in Westwood and Santa Monica have been named to U.S. News and World Report's 2015-2016 Best Hospitals Honor Roll. UCLA, which previously ranked No. 5 in the country, tied for No. 3 this year.

22 Jul 2015

Tips to prevent, treat black widow and brown recluse spider bites

Most spiders are non-venomous and most spider bites are harmless. They may cause some local redness and pain, but can usually be managed at home by washing, applying ice and keeping the area clean.

22 Jul 2015

Medical News

Gene responsible for cancer growth plays unexpected role in prostate cancer

New TCR therapy demonstrates encouraging clinical responses in patients with multiple myeloma

Multi-year project aims to develop, improve clinical research tools for studying ASD

Study shows regions of genome underlying IBD consistent around the world

EGPAF calls for prioritizing HIV treatment among children

Dairy products could make probiotics more effective

New research examines why some gaming habits escalating among adolescents

Heidelberg University scientists gain new insight into cytotoxic effect of Ebola virus

Study shows glitazone antidiabetic drug may reduce risk of Parkinson’s disease

KalVista raises $33 million in Series B financing to support development of plasma kallikrein inhibitors

Researchers report new drug combination that effectively treats HCV patients co-infected with HIV

Unique collaboration aims to transform geriatric care in North Texas

UCLA's Jonsson Comprehensive Cancer Center named among top 10 cancer centers in nation

Tyrone Regional Health Network signs letter of intent to become member of Penn State Health

Research suggests that only one in three older Americans have diabetes under control

Study examines link between use of diabetes drug pioglitazone and increased risk of bladder cancer

Use of dicloxacillin linked to INR decrease in patients taking vitamin K antagonists

AS03 and MF59 adjuvants increase immune responses to two doses of H7N9 influenza vaccine

UCLA Health's hospitals named among nation's best in U.S. News and World Report

Tips to prevent, treat black widow and brown recluse spider bites

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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