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Autophagy: A new approach to fighting tuberculosis

A new approach to combatting tuberculosis would take advantage of a complex, natural process called autophagy that the human body uses to recycle nutrients, remove damaged cell components, eliminate invading bacteria, and respond to inflammation.

16 Apr 2015

Study: BPA exposure during pregnancy affects fertility, reproductive function

When scientists exposed pregnant mice to levels of bisphenol A equivalent to those considered safe in humans, three generations of female mouse offspring experienced significant reproductive problems, including declines in fertility, sexual maturity and pregnancy success, the scientists report in the journal Toxicology and Applied Pharmacology.

16 Apr 2015

New research links megalin protein with malignant melanomas

Today it is not possible to predict spreading from malignant melanomas. Melanoma metastases are furthermore extremely difficult to eliminate as traditional treatment such as chemotherapy and radiotherapy is mostly ineffective. Only ten per cent of the patients survive once they reach an advanced stage with distant metastases.

16 Apr 2015

Women with ovarian cancer need to be tested for BRCA genes

The genes BRCA1 and BRCA2 play a significant role in hereditary breast and ovarian cancers. Recent media attention has focused on American actress Angelina Jolie's decision to have her ovaries and fallopian tubes surgically removed after genetic testing for such cancers.

16 Apr 2015

Novel findings may hold promise for children, adults with mitochondrial disorders

Rooted in malfunctions in the tiny power plants that energize our cells, mitochondrial disorders are notoriously complex and variable, with few effective treatments. Now, novel findings in microscopic worms may hold great promise for children and adults with mitochondrial disorders

16 Apr 2015

New set of molecules could carry medicines into cells

Just as a scientist dressed in a lab coat and goggles might get stuck behind the velvet rope at a trendy bar, many otherwise good drugs can't get inside cells if they don't look the part. In a report published this week in ACS Central Science, researchers report a new set of molecules that could ferry medicines into cells by taking on the right charge and shape, easily sliding past lipid membranes.

16 Apr 2015

UCLA researchers find that 59% of California physicians support Patient Protection and ACA

UCLA researchers have found that 77 percent of California primary care and specialty physicians understand the basics of the Patient Protection and Affordable Care Act and 59 percent support it. The survey, conducted by doctors from the UCLA department of family medicine, was published in the peer-reviewed journal Family Medicine.

16 Apr 2015

OSU study finds that injury prevention programs are not being used in high schools

Injury prevention programs can help reduce ankle, knee and other lower extremity injuries in sports, but the programs are not being widely used in high schools, a new study from Oregon State University has found.

16 Apr 2015

SGK1 enzyme protects brain cells in animal models of Parkinson's disease

Scientists from the Florida campus of The Scripps Research Institute have found how a widely known but little-studied enzyme protects brain cells in models of Parkinson's disease.

16 Apr 2015

Scientists identify way to potentially predict progression in patients with early form of breast cancer

Scientists in Manchester have identified a way to potentially predict which patients with an early form of breast cancer will experience disease progression.

16 Apr 2015

New metabolic blood profile method could help predict breast cancer

According to the World Health Organization, breast cancer is the most common cancer in women both in the developed and less developed world, and in the long term the scientists hope that the new method will lead to better prevention and early treatment of the disease.

16 Apr 2015

NIST researchers develop new 2D NMR fingerprinting method to measure monoclonal antibodies

National Institute of Standards and Technology researchers at the Institute for Bioscience and Biotechnology Research have demonstrated the most precise method yet to measure the structural configuration of monoclonal antibodies (mAbs), an important factor in determining the safety and efficacy of these biomolecules as medicines.

16 Apr 2015

Oxycodone-related deaths drop 25% after implementation of Prescription Drug Monitoring Program

Oxycodone-related deaths dropped 25 percent after Florida implemented its Prescription Drug Monitoring Program in late 2011 as part of its response to the state's prescription drug abuse epidemic, according to a team of UF Health researchers. The drop in fatalities could stem from the number of health care providers who used the program's database to monitor controlled substance prescriptions.

16 Apr 2015

NIH-supported clinical trial to test statin use in patients with HIV-related cardiovascular disease

Researchers have begun enrolling participants in a multicenter international clinical trial to test whether statin administration can reduce the risk for major adverse cardiovascular events, such as heart attacks, strokes, and heart disease, in people with HIV infection. The trial is supported by the National Institutes of Health's National Heart, Lung, and Blood Institute and National Institute of Allergy and Infectious Diseases.

16 Apr 2015

Houston Methodist researchers discover new, ex vivo lung cancer model to study tumor progression

Without good models to study cancer metastasis -- the spread of cancer cells from one organ to another -- cancer researchers have struggled to understand tumor progression fully, and new therapies targeting the main causes of death are slow to come.

16 Apr 2015

India and Canada announce funding to improve maternal, child health in India

Grand Challenges Canada, funded by the Government of Canada, and the Grand Challenges India initiative of the Department of Biotechnology, Government of India, today announced an investment of $2.5 million (CAD) in five health innovations in India.

16 Apr 2015

UH Seidman Cancer Center uses SpaceOAR System to perform first-ever prostate cancer treatment

The radiation oncology team at UH Seidman Cancer Center at UH Geauga Medical Center performed the first-ever prostate cancer treatment on April 3 using a newly approved device. The device, called SpaceOAR System, enhances the efficacy of radiation treatment by protecting organs surrounding the prostate. The device, a temporary injectable gel, received FDA clearance on April 1.

16 Apr 2015

WGU announces new scholarship opportunity for nursing students

Western Governors University has announced a new scholarship opportunity for nursing master's degree students honoring the leadership and healthcare career of outgoing American Organization of Nurse Executives President Linda Knodel.

16 Apr 2015

Moirai Orthopaedics receives FDA approval for IDE application to initiate clinical study of PIR System

Moirai Orthopaedics, L.L.C., an orthopaedic implant development company based in Metairie, Louisiana, is pleased to announce it has received approval from the US Food and Drug Administration for its Investigational Device Exemption (IDE) application to initiate clinical study of the company's Pyrocarbon Implant Replacement (PIR) System.

16 Apr 2015

Japanese MHLW grants priority review for AbbVie's investigational hepatitis C treatment

AbbVie today announced that the Japanese Ministry of Health, Labour and Welfare has granted priority review for its investigational, two direct-acting antiviral treatment of ombitasvir/paritaprevir/ritonavir.

16 Apr 2015

Medical News

Autophagy: A new approach to fighting tuberculosis

Study: BPA exposure during pregnancy affects fertility, reproductive function

New research links megalin protein with malignant melanomas

Women with ovarian cancer need to be tested for BRCA genes

Novel findings may hold promise for children, adults with mitochondrial disorders

New set of molecules could carry medicines into cells

UCLA researchers find that 59% of California physicians support Patient Protection and ACA

OSU study finds that injury prevention programs are not being used in high schools

SGK1 enzyme protects brain cells in animal models of Parkinson's disease

Scientists identify way to potentially predict progression in patients with early form of breast cancer

New metabolic blood profile method could help predict breast cancer

NIST researchers develop new 2D NMR fingerprinting method to measure monoclonal antibodies

Oxycodone-related deaths drop 25% after implementation of Prescription Drug Monitoring Program

NIH-supported clinical trial to test statin use in patients with HIV-related cardiovascular disease

Houston Methodist researchers discover new, ex vivo lung cancer model to study tumor progression

India and Canada announce funding to improve maternal, child health in India

UH Seidman Cancer Center uses SpaceOAR System to perform first-ever prostate cancer treatment

WGU announces new scholarship opportunity for nursing students

Moirai Orthopaedics receives FDA approval for IDE application to initiate clinical study of PIR System

Japanese MHLW grants priority review for AbbVie's investigational hepatitis C treatment

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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