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PAION initiates Remimazolam Phase 3 trial in patients undergoing colonoscopy

PAION, Inc., a wholly owned subsidiary of PAION AG, today announced the initiation of a U.S. Phase 3 clinical trial of Remimazolam, an ultra-short-acting sedative/anesthetic, for procedural sedation in patients undergoing colonoscopy.

31 Mar 2015

Roche launches new protein melting application for real-time PCR LightCycler 1536 instrument

Roche announced today the introduction of a new protein melting application for its high-throughput, real-time PCR LightCycler 1536 instrument. The fully automated platform now allows life science researchers to perform thermal shift assays (TSAs) in 1536-well applications quickly and consistently.

From Roche Sequencing and Life Science 31 Mar 2015

PAREXEL introduces new version of Regulatory Information Management platform

PAREXEL International Corporation, a leading global biopharmaceutical services provider, today introduced the latest version of its Regulatory Information Management (RIM) platform: LIQUENT InSight 6.0.

From Parexel 31 Mar 2015

Aeterna Zentaris inks Material Transfer Agreement with MUSC

Aeterna Zentaris Inc. today announced that it has agreed to transfer its discovery library of roughly 100,000 unique compounds to the South Carolina Center for Therapeutic Discovery & Development (the Center) pursuant to a just concluded Material Transfer Agreement.

31 Mar 2015

Study provides new estimates of opioid misuse, addiction

New estimates suggest that 20 to 30 percent of opioid analgesic drugs prescribed for chronic pain are misused, while the rate of opioid addiction is approximately 10 percent, reports a study in the April issue of PAIN, the official journal of the International Association for the Study of Pain.

31 Mar 2015

New analysis raises questions about common use of antidepressant drugs for anxiety disorders

A new analysis reported in JAMA Psychiatry raises serious questions about the increasingly common use of second-generation antidepressant drugs to treat anxiety disorders.

31 Mar 2015

Ultrafine particle exposure may affect cardiac function

The adverse health effects caused by fine particles have been known for some time. In addition, ultrafine particles appear to play a significant role in cardiac function - even if an individual is exposed to these for only a few minutes, as scientists of Helmholtz Zentrum München have now been able to show.

31 Mar 2015

Study shows stark variation in genetic testing services for inherited eye conditions in England

New research from The University of Manchester published in the Journal of Community Genetics reveals a stark variation in genetic testing services for inherited eye disease in England.

31 Mar 2015

New study sheds light on natural small molecule with antimicrobial effects

Scientists from the Florida campus of The Scripps Research Institute have uncovered the unique mechanism of a powerful natural product with wide-ranging antifungal, antibacterial, anti-malaria and anti-cancer effects.

31 Mar 2015

China Pharma's revenue decreases 24% to $24.9 million in fiscal year 2014

China Pharma Holdings, Inc., an NYSE MKT listed corporation with its fully-integrated specialty pharmaceuticals subsidiary based in China, today announced financial results for the year ended December 31, 2014.

31 Mar 2015

Biomedical researchers successfully convert microbubble technology into nanoparticles

Biomedical researchers led by Dr. Gang Zheng at Princess Margaret Cancer Centre have successfully converted microbubble technology already used in diagnostic imaging into nanoparticles that stay trapped in tumours to potentially deliver targeted, therapeutic payloads.

31 Mar 2015

Genetic markers may predict tumor samples that respond to treatment

Patients with chronic myelomonocytic leukemia have limited treatment options, and those that exist are effective only in fewer than half of patients. Now, a new study identifies a panel of genetic markers that predicted which tumor samples would likely respond to treatment.

31 Mar 2015

Cardio3 BioSciences announces successful completion of futility analysis for C-Cure

Cardio3 BioSciences, a leader in engineered cell therapy treatments, today announced the successful completion of a futility analysis for C-Cure, its lead cell therapy for congestive heart failure, currently being evaluated in a Phase III clinical trial in Europe and Israel (CHART-1).

31 Mar 2015

Researchers report correlative links between family income, brain structure in children

Characterizing associations between socioeconomic factors and children's brain development, a team including investigators from nine universities across the country reports correlative links between family income and brain structure. Relationships between the brain and family income were strongest in the lowest end of the economic range - suggesting that interventional policies aimed at these children may have the largest societal impact.

31 Mar 2015

Minimally invasive laparoscopic surgery significantly lowers health care costs

Adding to the clinical benefits and improved patient outcomes associated with minimally invasive surgery, Medtronic highlighted a study published in the March 25 online edition of JAMA Surgery. The new study demonstrated that patients who underwent laparoscopic colectomy procedures required fewer days of health care utilization and the health care system spent less on their acute and follow-up care than those who underwent traditional open surgery.

31 Mar 2015

Researchers create 3D skin maps to detect molecular, microbial variations across the body

Researchers at the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences used information collected from hundreds of skin swabs to produce three-dimensional maps of molecular and microbial variations across the body.

31 Mar 2015

New research reveals how a deadly fungus grows and kills immune cells

New research from the University of Toronto has scientists re-thinking how a lethal fungus grows and kills immune cells. The study hints at a new approach to therapy for Candida albicans, one of the most common causes of bloodstream infections.

31 Mar 2015

Complete review of amyloid-beta protein behind Alzheimer's disease

"It will still take many years to understand the mechanisms leading to the formation of the characteristic plaques seen in brains affected by Alzheimer's disease", explains Alessandro Laio, SISSA professor. "We know they are mostly a build-up of amyloid-beta peptide, the protein that research is currently focusing on". And, as of today, all those involved in biomolecular research on Alzheimer's will have access to a new and important instrument: an extensive and complete review of all scientific knowledge about this "killer protein" has in fact just been published in the journal Chemical Reviews.

31 Mar 2015

Ultrasound safer than other imaging modalities for imaging female pelvis, say OB/GYN experts

Ultrasound technology has evolved dramatically in recent years. A group of noted obstetricians and gynecologists maintain that ultrasound is more cost-effective and safer than other imaging modalities for imaging the female pelvis and should be the first imaging modality used for patients with pelvic symptoms.

31 Mar 2015

Broad Institute expands collaboration with Bayer to develop new cardiovascular therapies

The Broad Institute of MIT and Harvard have expanded their collaboration with Bayer HealthCare to include cardiovascular genomics and drug discovery. The goal of this new part of the alliance is to leverage insights from human genetics to help create new cardiovascular therapies.

31 Mar 2015

Medical News

PAION initiates Remimazolam Phase 3 trial in patients undergoing colonoscopy

Roche launches new protein melting application for real-time PCR LightCycler 1536 instrument

PAREXEL introduces new version of Regulatory Information Management platform

Aeterna Zentaris inks Material Transfer Agreement with MUSC

Study provides new estimates of opioid misuse, addiction

New analysis raises questions about common use of antidepressant drugs for anxiety disorders

Ultrafine particle exposure may affect cardiac function

Study shows stark variation in genetic testing services for inherited eye conditions in England

New study sheds light on natural small molecule with antimicrobial effects

China Pharma's revenue decreases 24% to $24.9 million in fiscal year 2014

Biomedical researchers successfully convert microbubble technology into nanoparticles

Genetic markers may predict tumor samples that respond to treatment

Cardio3 BioSciences announces successful completion of futility analysis for C-Cure

Researchers report correlative links between family income, brain structure in children

Minimally invasive laparoscopic surgery significantly lowers health care costs

Researchers create 3D skin maps to detect molecular, microbial variations across the body

New research reveals how a deadly fungus grows and kills immune cells

Complete review of amyloid-beta protein behind Alzheimer's disease

Ultrasound safer than other imaging modalities for imaging female pelvis, say OB/GYN experts

Broad Institute expands collaboration with Bayer to develop new cardiovascular therapies

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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