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Gene regulatory code remained same across the evolution

The language used in the switches that turn genes on and off has remained the same across millions of years of evolution, according to a new study led by researchers at Karolinska Institutet in Sweden. The findings, which are published in the scientific journal "eLife", indicate that the differences between animals reside in the content and length of the instructions that are written using this conserved language.

23 Mar 2015

Discovery may lead to new potential treatment for drug-resistant melanoma

In the last several years, targeted therapies - drugs that directly impact specific genes and proteins involved in the progression of cancer - have been approved for a wide variety of cancers, including melanoma, the deadliest form of skin cancer. Now, researchers at The Wistar Institute have discovered one way in which melanoma becomes resistant to a particular form of targeted therapy, and understanding this phenomenon may lead to a new melanoma target or prompt new designs of these treatments.

23 Mar 2015

Researchers find key step in understanding genetic mechanism of plants' environmental adaptability

A fundamental question pursued by plant scientists worldwide for the past decade has been answered by researchers led by the University of Sydney in Australia.

23 Mar 2015

Anticoagulant drug bivalirudin shows mixed results in MATRIX trial

Patients with acute coronary syndrome undergoing angioplasty who received the anticoagulant drug bivalirudin did not show significant improvements in either of two co-primary endpoints--a composite of rate of death, heart attack or stroke at 30 days, or a composite of those events plus major bleeding--as compared to patients receiving standard anticoagulation therapy, according to a study presented at the American College of Cardiology's 64th Annual Scientific Session.

23 Mar 2015

Pathogen may cause high levels of virulence in closely-related hosts

When viruses such as influenza and Ebola jump from one species to another, their ability to cause harm can change dramatically, but research from the University of Cambridge shows that it may be possible to predict the virus's virulence by looking at how deadly it is in closely-related species.

23 Mar 2015

Using arm as access point for catheter-based heart procedures lowers risk of major bleeding, death

Patients with acute coronary syndrome undergoing coronary angiogram, a procedure used to assess blockages in the heart's arteries, had a significantly lower risk of major bleeding and death if their interventional cardiologist accessed the heart through an artery in the arm rather than the groin, according to research presented at the American College of Cardiology's 64th Annual Scientific Session.

23 Mar 2015

Study: Blood tests for women taking spironolactone to treat hormonal acne are unnecessary

A new study by researchers at Brigham and Women's Hospital has found that for young, healthy women taking spironolactone to treat hormonal acne, frequent office visits and blood draws are an unnecessary health care expense.

23 Mar 2015

Climate change could accelerate emergence of vector-borne diseases in UK

Climate change could accelerate the emergence of vector-borne diseases such as chikungunya, dengue fever, and West Nile virus in the UK, warn leading public health experts Dr Jolyon Medlock and Professor Steve Leach from the Emergency Response Department at Public Health England, writing in The Lancet Infectious Diseases journal.

23 Mar 2015

Women who learn stress management techniques during breast cancer treatment have better quality of life

A new study shows that providing women with skills to manage stress early in their breast cancer treatment can improve their mood and quality of life many years later. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings suggest that women given the opportunity to learn stress management techniques during treatment may benefit well into survivorship.

23 Mar 2015

Thomson Reuters releases 2015 edition of annual Drugs to Watch report

The Intellectual Property and Science business of Thomson Reuters, the world's leader in intelligent information for businesses and professionals, today released the 2015 edition of its annual Drugs to Watch report.

23 Mar 2015

MEDITE announces granting of German priority patent for Histology 'Lab-in-one Automation' System

MEDITE Cancer Diagnostics, Inc., specializing in the development, manufacturing and marketing of superior molecular biomarkers and premium medical devices for detection, risk assessment and diagnosis of cancer and related diseases announced the recent decision of the German Patent Register to grant MEDITE the German priority patent for its Histology "Lab-in-one Automation" System.

22 Mar 2015

Study finds no added benefit from sipuleucel-T in men with metastatic prostate cancer

Sipuleucel-T (trade name Provenge) has been approved since September 2014 for men with metastatic prostate cancer who have few or no symptoms and do not yet require chemotherapy. In the dossier assessment conducted by the German Institute for Quality and Efficiency in Health Care (IQWiG) in January 2015, no added benefit could be derived for sipuleucel-T.

22 Mar 2015

AAPM announces recipients of 2015 Pain Medicine Fellowship Excellence Award

The American Academy of Pain Medicine is pleased to announce its 2015 Pain Medicine Fellowship Excellence Award Recipients in recognition of a Pain Medicine Fellowship Program that provides an exceptional learning experience to its fellows, preparing them to deliver the highest standard of care to patients with pain.

22 Mar 2015

MRD-directed therapy helps boost survival of young leukemia patients

Measuring the concentration of leukemia cells in patient bone marrow during the first 46 days of chemotherapy should help boost survival of young leukemia patients by better matching patients with the right intensity of chemotherapy. St. Jude Children's Research Hospital investigators led the research, which appears in the March 20 edition of the journal Lancet Oncology.

22 Mar 2015

Experts call for global review of sepsis guidelines

Experts are calling for a global review of guidelines used to diagnose sepsis, after a study found one in eight patients with infections severe enough to need admission to an Intensive Care Unit in Australia and New Zealand, did not meet current criteria.

22 Mar 2015

MED15 may serve as prognostic marker for HNSCC recurrence

A new study provides the first evidence that the mediator complex subunit 15 (MED15) may play a crucial role in the pathophysiology of head and neck squamous cell carcinoma (HNSCC). MED15 overexpression was found to be associated with higher mortality rates in HNSCC patients with cancer recurrence, particularly in oral cavity/oropharyngeal tumors, according to the study published in The American Journal of Pathology.

21 Mar 2015

Hypermethylation serves as protective barrier inhibiting development of ALS, FTD

Penn Medicine researchers have discovered that hypermethylation - the epigenetic ability to turn down or turn off a bad gene implicated in 10 to 30 percent of patients with Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Degeneration (FTD) - serves as a protective barrier inhibiting the development of these diseases.

21 Mar 2015

Medical News

Gene regulatory code remained same across the evolution

Discovery may lead to new potential treatment for drug-resistant melanoma

Researchers find key step in understanding genetic mechanism of plants' environmental adaptability

Anticoagulant drug bivalirudin shows mixed results in MATRIX trial

Pathogen may cause high levels of virulence in closely-related hosts

Using arm as access point for catheter-based heart procedures lowers risk of major bleeding, death

Study: Blood tests for women taking spironolactone to treat hormonal acne are unnecessary

Climate change could accelerate emergence of vector-borne diseases in UK

Women who learn stress management techniques during breast cancer treatment have better quality of life

Thomson Reuters releases 2015 edition of annual Drugs to Watch report

MEDITE announces granting of German priority patent for Histology 'Lab-in-one Automation' System

Study finds no added benefit from sipuleucel-T in men with metastatic prostate cancer

AAPM announces recipients of 2015 Pain Medicine Fellowship Excellence Award

MRD-directed therapy helps boost survival of young leukemia patients

Experts call for global review of sepsis guidelines

MED15 may serve as prognostic marker for HNSCC recurrence

Hypermethylation serves as protective barrier inhibiting development of ALS, FTD

AAPM announces winners of Pain Medicine 2015 Awards for exceptional service

Amgen seeks marketing approval of Repatha (evolocumab) in Japan for treatment of high cholesterol

Eli Lilly, Innovent Biologics announce biotech drug development collaborations in China

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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