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Whole genome sequencing can help implement rapid-response infection control protocols

Whole genome sequencing can quickly isolate the specific strain of bacteria causing an outbreak, identify the source of contamination, and enable rapid infection prevention to stop the spread of infection, according to a study published today.

9 Jun 2015

Duration of antibiotic treatment can be cut by half for complicated abdominal infections

In a finding important for preventing the development of antibiotic-resistant superbugs, researchers at the University of Virginia School of Medicine and 22 other institutions have determined that the duration of antibiotic treatment for complicated abdominal infections can be cut by half and remain equally effective.

9 Jun 2015

New study suggests link between lower life satisfaction and sleep problems during midlife

A new study suggests that lower life satisfaction is linked to sleep problems during midlife. Respondents with higher life satisfaction reported shorter sleep onset latency (SOL). Sleep onset delay among those with low life satisfaction could be the result of worry and anxiety, as reported elsewhere. These findings support the idea that life satisfaction is interlinked with many measures of sleep and sleep quality, suggesting that improving one of these variables might result in improving the other.

9 Jun 2015

Severe restless legs syndrome associated with increased risk of stroke

A new study suggests that increased restless legs syndrome (RLS) severity is associated with subsequent increased risk of stroke.

9 Jun 2015

NGS mutational testing can help detect patients with Barrett's esophagus

Barrett's esophagus (BE) develops in a subset of patients with gastroesophageal reflux disease (GERD) and can increase the risk of developing cancer of the esophagus. Although periodic surveillance for cancer is recommended for BE patients, these examinations may fail to identify pre-cancerous dysplasia and early cancers.

9 Jun 2015

Phase II clinical trial of Linsitinib launched in patients with advanced Ewing sarcoma

EUROSARC, European Clinical trials in Rare Sarcomas within an integrated translational trial network, has launched a phase II trial of Linsitinib for patients with relapsed and/or refractory Ewing Sarcoma. The trial, EORTC 1225 / OCTO 038, aims to establish pharmacodynamic responses in Ewing sarcoma tumors to Linsitinib using functional imaging and biopsies, and toxicity and clinical outcomes.

9 Jun 2015

Researchers develop device to diagnose bacterial meningitis in babies

Currently the only test to diagnose bacterial meningitis in babies is through a lumbar puncture, a painful and difficult procedure to perform. For this reason, a group of biomedical engineers decided to search for an alternative and developed a portable device that can detect this illness with a simple ultrasound scan of the fontanelle.

9 Jun 2015

UC Davis funds BRAIN-STIM program to uncover potential treatments for neurodegenerative disorders

In 2013, President Obama announced the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, unveiling plans to make a bold investment to understand the human mind with the intent to uncover ways to prevent, treat and cure brain disorders like Alzheimer's, autism, and epilepsy.

9 Jun 2015

Earlier introduction of palliative care in advanced cancer patients associated with lower hospital costs

Earlier introduction of palliative care for patients hospitalized with advanced cancer is associated with lower hospital costs, according to a new study published in the Journal of Clinical Oncology.

9 Jun 2015

Weight loss reduces asthma severity in obese adults, finds study

A Canadian study published in the June issue of the journal CHEST found weight loss reduced asthma severity as measured by airway hyperresponsiveness (AHR) in obese adults.

9 Jun 2015

Researchers pinpoint gene that may solve the root cause of diabetes

Professor Jeffery Tessem has pinpointed a gene that may help solve a riddle at the root of diabetes, the high-blood-sugar disease affecting 400 million people worldwide.

9 Jun 2015

Electroporation technique brings higher efficiency, higher throughput genome engineering in animal models

Jackson Laboratory researchers have shown that using an electric current to deliver the CRISPR/Cas9 system, in order to engineer genetic changes in laboratory mice, is highly efficient and significantly improves the system's throughput.

9 Jun 2015

Greater life satisfaction in older adults linked to reduced risk of mortality

In a study just published by researchers at Chapman University, findings showed that greater life satisfaction in adults older than 50 years of age is related to a reduced risk of mortality.

9 Jun 2015

Glucose-control drug sitagliptin does not raise risk of cardiovascular events

A clinical trial of the glucose-control drug sitagliptin among patients with type 2 diabetes and established cardiovascular disease has found it did not raise the risk of major adverse cardiovascular events.

9 Jun 2015

Despite low value and high costs, certain preoperative tests still common in U.S.

Professional physician associations consider certain routine tests before elective surgery to be of low value and high cost, and have sought to discourage their utilization.

9 Jun 2015

Study: Children with TBI more likely to experience daytime sleepiness, sleep disturbances

A new study suggests that children with traumatic brain injuries (TBI) have poorer sleep and more daytime sleepiness in comparison to healthy children.

9 Jun 2015

Scientists develop computational method to study link between birth month and disease risk

Columbia University scientists have developed a computational method to investigate the relationship between birth month and disease risk.

9 Jun 2015

Protective antibody response could be effective in preventing mother-to-child HIV transmission

How most babies are protected from acquiring HIV from their infected mothers has been a matter of scientific controversy.

9 Jun 2015

Simulator-based driver assessment differentiates between skilled and non-skilled drivers

Passing the state driver's licensing test does not always mean new drivers have the critical skills they need to drive safely.

9 Jun 2015

Frankfurt researchers decode molecular details that provide better understanding of neurodegenerative diseases

Quality control is important - this is not only applicable to industrial production but also true for all life processes. However, whereas an enterprise can start a large-scale recall in case of any doubt, defects in the quality control systems of cells are often fatal.

9 Jun 2015

Medical News

Whole genome sequencing can help implement rapid-response infection control protocols

Duration of antibiotic treatment can be cut by half for complicated abdominal infections

New study suggests link between lower life satisfaction and sleep problems during midlife

Severe restless legs syndrome associated with increased risk of stroke

NGS mutational testing can help detect patients with Barrett's esophagus

Phase II clinical trial of Linsitinib launched in patients with advanced Ewing sarcoma

Researchers develop device to diagnose bacterial meningitis in babies

UC Davis funds BRAIN-STIM program to uncover potential treatments for neurodegenerative disorders

Earlier introduction of palliative care in advanced cancer patients associated with lower hospital costs

Weight loss reduces asthma severity in obese adults, finds study

Researchers pinpoint gene that may solve the root cause of diabetes

Electroporation technique brings higher efficiency, higher throughput genome engineering in animal models

Greater life satisfaction in older adults linked to reduced risk of mortality

Glucose-control drug sitagliptin does not raise risk of cardiovascular events

Despite low value and high costs, certain preoperative tests still common in U.S.

Study: Children with TBI more likely to experience daytime sleepiness, sleep disturbances

Scientists develop computational method to study link between birth month and disease risk

Protective antibody response could be effective in preventing mother-to-child HIV transmission

Simulator-based driver assessment differentiates between skilled and non-skilled drivers

Frankfurt researchers decode molecular details that provide better understanding of neurodegenerative diseases

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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