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NIAID partners with Liberian government to test ZMapp drug for Ebola virus disease

In partnership with the Liberian government, the National Institute of Allergy and Infectious Diseases today launched a clinical trial to obtain safety and efficacy data on the investigational drug ZMapp as a treatment for Ebola virus disease. The study, which will be conducted in Liberia and the United States, is a randomized controlled trial enrolling adults and children with known Ebola virus infection.

27 Feb 2015

Researchers reveal role of abdominal muscles in muscular dystrophy process

The muscular dystrophies are known to target various muscle groups differentially. In addition to making limb muscles weak, muscular dystrophy (MD) can also lead to decreased function of specific muscles involved in respiration causing breathing difficulties as well as leading to cardiac problems.

27 Feb 2015

New tool provides molecular details about how mutations affect cellular processes

Today in the journal Nature Methods, the laboratory headed by ICREA researcher Patrick Aloy, at the Institute for Research in Biomedicine, presents a computational tool that allows a greater understanding of the genetic causes of complex diseases such as cancer, Alzheimer's and diabetes.

27 Feb 2015

TOMS Bag Collection launched to address issue of maternal health worldwide

TOMS – the company known for starting a global movement through its One for One business model – has launched its fourth and newest product, the TOMS Bag Collection, addressing the issue of maternal health worldwide.

27 Feb 2015

Young women veterans referred for cardiac tests more likely to be depressed than men veterans

Women veterans who had specialized heart tests were younger and more likely to be obese, depressed and suffer from post-traumatic stress disorder than men veterans, according to a study published in an American Heart Association journal.

27 Feb 2015

ERT signs definitive agreement to acquire PHT

ERT, a leading global solution provider for high-quality patient safety and efficacy endpoint data collection, and PHT Corporation, the eClinical innovator leading the adoption of patient-driven mobile apps for improved clinical research, announced today that they have signed a definitive agreement under which ERT will acquire PHT.

27 Feb 2015

Chiasma closes $70 million Series E financing round

Chiasma, Inc., a U.S. privately-held biopharma company developing octreotide capsules, its lead product for the orphan condition acromegaly, today announced the closing of a $70 million Series E financing round.

27 Feb 2015

Study shows efficacy of YONDELIS (trabectedin) in patients with soft-tissue sarcoma

PharmaMar announced that the European Journal of Cancer published online data from a large retrospective study with soft-tissue sarcoma (STS) patients carried out at 25 French centers confirming that in routine practice YONDELIS (trabectedin) shows comparable or better clinical outcomes than those observed in clinical trials.

27 Feb 2015

UConn chemists develop more advanced peanut allergy test

Current peanut allergy tests are not very reliable when it comes to diagnosing the severity of an individual's allergic reaction, which can range from hives to life-threatening anaphylactic shock.

27 Feb 2015

Study evaluates dietary impact of whole fruit and 100% juice consumption

When it comes to meeting the recommended servings of fruit per day, 100% juice in the diet makes a difference. According to a new study from the University of Washington Center for Public Health, published on-line in Nutrition Journal, Americans consume just over one cup of fruit per day, on average.

27 Feb 2015

Study: Levodopa-carbidopa intestinal gel improves quality of life in advanced PD patients

Although levodopa remains the "gold standard" to effectively control motor deficits in the treatment of early stage Parkinson's disease (PD), it loses effectiveness as the disease progresses. After four to six years of treatment with oral medications for Parkinson's disease, about 40% of patients experience lack of muscle control (dyskinesias), end-of-dose wearing off, and fluctuations in "On/Off" states.

27 Feb 2015

Life-saving bone marrow transplants are not available to all who need them

Bone marrow (hematopoietic stem cell) transplant is a life saving treatment for patients with blood cancer that replaces blood stem cells lost to disease or chemotherapy. However, for each patient to benefit a matching donor must be found to provide the stem cells for transplant.

27 Feb 2015

Study: Persistent insomnia increases mortality risk

A connection between persistent insomnia and increased inflammation and mortality has been identified by a group of researchers from the University of Arizona. Their study, published in The American Journal of Medicine, found that people who suffer from persistent insomnia are at greater risk than those who experience intermittent insomnia.

27 Feb 2015

Vitamin D, omega-3 fatty acids may optimize brain serotonin concentrations and function

Although essential marine omega-3 fatty acids and vitamin D have been shown to improve cognitive function and behavior in the context of certain brain disorders, the underlying mechanism has been unclear. In a new paper published in FASEB Journal by Rhonda Patrick, PhD and Bruce Ames, PhD of Children's Hospital Oakland Research Institute, serotonin is explained as the possible missing link tying together why vitamin D and marine omega-3 fatty acids might ameliorate the symptoms associated with a broad array of brain disorders.

27 Feb 2015

Study shows physical similarities, differences between extrovert types in the brain

Everyday experience and psychological studies alike tell us that there are two different types of extroverts: The gregarious "people-persons" who find reward in sharing affection and affiliation with others, and the ambitious "go-getters" who flash those bright-white smiles in their pursuit of achievement and leadership agendas.

27 Feb 2015

Pediatric patients who receive quick antibiotics for fever, neutropenia have reduced PICU needs

A University of Colorado Cancer Center study published in the journal Pediatric Blood & Cancer shows that pediatric cancer patients who receive antibiotics within 60 minutes of reporting fever and showing neutropenia (low neutrophil count), go on to have decreased intensive care consultation rate and lower mortality compared with patients who receive antibiotics outside the 60-minute window.

27 Feb 2015

Articles discuss use of ICF in clinical practice, research related to neurorehabilitation

Use of the International Classification of Functioning, Disability and Health (ICF) has increased significantly over the last decade. The current issue of NeuroRehabilitation features a series of insightful articles that provide examples of how the ICF can be successfully implemented in clinical practice and research related to neurorehabilitation, ultimately benefiting patient care.

27 Feb 2015

LGTmedical issued U.S. patent for Kenek Core audio waveform technology

LionsGate Technologies, Inc., a privately-held medical device company, announced today that the U.S. Patent and Trademark Office has issued a patent for its pulse oximetry technology based on the Kenek Core proprietary audio waveform platform.

27 Feb 2015

Single-step fermentative method may facilitate industrial-scale statin drug production

University of Manchester researchers, together with industrial partner DSM, have developed a single-step fermentative method for the production of leading cholesterol-lowering drug, pravastatin, which will facilitate industrial-scale statin drug production.

27 Feb 2015

Varian reports progress towards making advanced treatments available for cancer patients in Africa

Varian Medical Systems, world leader in radiation therapy, is today reporting progress towards its goal of making advanced treatments systems more available for cancer patients across Africa. The company is presenting to government and healthcare leaders at the 2nd Africa Healthcare Summit.

27 Feb 2015

Medical News

NIAID partners with Liberian government to test ZMapp drug for Ebola virus disease

Researchers reveal role of abdominal muscles in muscular dystrophy process

New tool provides molecular details about how mutations affect cellular processes

TOMS Bag Collection launched to address issue of maternal health worldwide

Young women veterans referred for cardiac tests more likely to be depressed than men veterans

ERT signs definitive agreement to acquire PHT

Chiasma closes $70 million Series E financing round

Study shows efficacy of YONDELIS (trabectedin) in patients with soft-tissue sarcoma

UConn chemists develop more advanced peanut allergy test

Study evaluates dietary impact of whole fruit and 100% juice consumption

Study: Levodopa-carbidopa intestinal gel improves quality of life in advanced PD patients

Life-saving bone marrow transplants are not available to all who need them

Study: Persistent insomnia increases mortality risk

Vitamin D, omega-3 fatty acids may optimize brain serotonin concentrations and function

Study shows physical similarities, differences between extrovert types in the brain

Pediatric patients who receive quick antibiotics for fever, neutropenia have reduced PICU needs

Articles discuss use of ICF in clinical practice, research related to neurorehabilitation

LGTmedical issued U.S. patent for Kenek Core audio waveform technology

Single-step fermentative method may facilitate industrial-scale statin drug production

Varian reports progress towards making advanced treatments available for cancer patients in Africa

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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