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Study: Growth hormone can improve social impairment in patients with Phelan-McDermid syndrome

A growth hormone can significantly improve the social impairment associated with autism spectrum disorder (ASD) in patients with a related genetic syndrome, according to a pilot study conducted at the Icahn School of Medicine at Mount Sinai and published yesterday on Pub Med, a public database of biomedical topics maintained by the National Institutes of Health (study originally published in the December 12 issue of the journal Molecular Autism).

20 Feb 2015

Global survey uncovers shocking lack of preparedness against rabies across Africa and Asia

The first global survey of rabies reporting systems, published this week, has uncovered a shocking lack of preparedness against this deadly disease across Africa and Asia. Accurate reporting of rabies cases to authorities is a critical first step in controlling rabies and preventing further outbreaks.

20 Feb 2015

New study finds that statins may not reduce risk for Parkinson's disease

The use of statins may not be associated with lowering risk for Parkinson's disease, according to a new study led by researchers at Penn State College of Medicine and National Institute of Environmental Health Sciences. The findings cast doubts on reports suggesting that the cholesterol-lowering medications may protect against this neurodegenerative brain disorder.

20 Feb 2015

Researchers demonstrate clinical efficacy of gallopamil in severe asthma patients

A team of Inserm researchers from the Cardio-Thoracic Research Centre of Bordeaux (Inserm/University of Bordeaux and Bordeaux University Hospital) has demonstrated the clinical efficacy of gallopamil in 31 patients with severe asthma. This chronic disease is characterised by remodelling of the bronchi, which exacerbates the obstruction of the airways already seen in "classic" asthma.

20 Feb 2015

Penn State researchers explore hydrogen sulfide's probable role in regulating blood pressure

Widely considered simply a malodorous toxic gas, hydrogen sulfide is now being studied for its probable role in regulating blood pressure, according to researchers.

20 Feb 2015

IUPUI's Jason Meyer awarded $1.8 million NIH grant to explore how glaucoma develops in stem cells

Jason Meyer, Ph.D., assistant professor of biology in the School of Science at Indiana University-Purdue University Indianapolis, has received a National Institutes of Health grant to study how glaucoma develops in stem cells created from skin cells genetically predisposed to the disease.

20 Feb 2015

Unhealthy foods outpace beneficial dietary changes in middle-income nations

In a first-of-its-kind analysis of worldwide dietary patterns, a team including researchers from the Friedman School of Nutrition Science and Policy at Tufts University and the Medical Research Council Epidemiology Unit, University of Cambridge found overall diet quality worsened across the world even as consumption of healthier foods increased in many countries.

20 Feb 2015

New research finds that synthetic flame retardants can cause metabolic and liver problems

Chemicals used as synthetic flame retardants that are found in common household items such as couches, carpet padding, and electronics have been found to cause metabolic and liver problems that can lead to insulin resistance, which is a major cause of obesity, according to new research from the University of New Hampshire.

20 Feb 2015

Study: Risk of uterine sarcoma fairly low in women following hysterectomy

Uterine sarcoma - a potentially aggressive type of cancer that forms in tissues in the uterus - was found in 0.22 % of women following a hysterectomy for benign conditions, a new large-scale study by the University of Michigan departments of Obstetrics and Gynecology, and Surgery finds.

20 Feb 2015

Two diagnostic tests can help identify children who require surgical treatment for appendicitis

Data from two standard diagnostic tests commonly obtained in children evaluated for abdominal pain--when combined--can improve the ability of emergency department physicians and pediatric surgeons to identify those patients who should be sent to the operating room for prompt removal of an inflamed appendix; those who may be admitted for observation; and those who may safely be discharged home, according to a new study published online as an "article in press" in the Journal of the American College of Surgeons.

20 Feb 2015

Evolution of two protein kinases may hold key to unlocking highly specific cancer drugs

This is the story of Abl and Src -- two nearly identical protein kinases whose evolution may hold the key to unlocking new, highly specific cancer drugs.

20 Feb 2015

MIT chemical engineers develop new type of self-healing hydrogel

Scientists are interested in using gels to deliver drugs because they can be molded into specific shapes and designed to release their payload over a specified time period. However, current versions aren't always practical because must be implanted surgically.

20 Feb 2015

Georgia State signs license agreement with Cisen to develop compounds for treating cancer

Georgia State University has signed a license agreement with Cisen Pharmaceutical Co. Ltd., a comprehensive pharmaceutical enterprise in China, to develop cancer-fighting compounds designed by Georgia State researcher Dr. Binghe Wang, in collaboration with Professor Muxiang Zhou of Emory University, a cancer biologist.

20 Feb 2015

Clinical study comparing effectiveness of three standard treatments for DME published in NEJM

Regeneron Pharmaceuticals, Inc. today announced that results from the National Institutes of Health-sponsored, Diabetic Retinopathy Clinical Research Network comparative effectiveness study in patients with Diabetic Macular Edema (Protocol T) were published in the New England Journal of Medicine and a corresponding slide set was posted online at DRCR.net.

20 Feb 2015

New study turns to epigenetics to look for new therapeutic targets to treat allergic diseases

Scientists have discovered over 30 new genes that predispose people to allergies and asthma, some of which could be targets for new drugs.

20 Feb 2015

Scientists identify promising new therapeutic target for prostate cancer

Keck Medicine of the University of Southern California scientists have found a promising new therapeutic target for prostate cancer. The findings offer evidence that a newly discovered member of a family of cell surface proteins called G-protein coupled receptors (GPCRs) promotes prostate cancer cell growth. The protein, GPR158, was found while the researchers were looking for new drug targets for glaucoma.

20 Feb 2015

Korean scientists produce flexible, stable monolayers of protein-bound gold nanoparticles

Free-standing nanoparticle films are of great interest for technical applications, such as the development of nanoelectronic devices. In the journal Angewandte Chemie, Korean scientists have introduced very flexible and stable monolayers of gold nanoparticles made by a self-assembly process based on protein aggregation. The films were used to coat wafers up to 10 cm in diameter.

20 Feb 2015

Targeting pericytes and ANG2 signaling may help treat certain breast cancers

Tumors require blood to emerge and spread. That is why scientists at The University of Texas MD Anderson Cancer Center believe that targeting blood vessel cells known as pericytes may offer a potential new therapeutic approach when combined with vascular growth factors responsible for cell death.

19 Feb 2015

InflectraTM (infliximab) patient registry reports interim results in the treatment of inflammatory bowel disease

Data have been presented today on the use of Hospira’s Inflectra (infliximab), the world’s first approved biosimilar monoclonal antibody (mAb), at the European Crohn’s and Colitis Organisation Inflammatory Bowel Diseases (ECCO-ibd) conference.

19 Feb 2015

Scientists develop promising new HIV vaccine agent

In a study that involved researchers from over a dozen institutions, the anti-HIV agent protected monkeys from every strain of HIV-1, HIV-2 and SIV (simian immunodeficiency virus) for at least 34 weeks.

19 Feb 2015

Medical News

Study: Growth hormone can improve social impairment in patients with Phelan-McDermid syndrome

Global survey uncovers shocking lack of preparedness against rabies across Africa and Asia

New study finds that statins may not reduce risk for Parkinson's disease

Researchers demonstrate clinical efficacy of gallopamil in severe asthma patients

Penn State researchers explore hydrogen sulfide's probable role in regulating blood pressure

IUPUI's Jason Meyer awarded $1.8 million NIH grant to explore how glaucoma develops in stem cells

Unhealthy foods outpace beneficial dietary changes in middle-income nations

New research finds that synthetic flame retardants can cause metabolic and liver problems

Study: Risk of uterine sarcoma fairly low in women following hysterectomy

Two diagnostic tests can help identify children who require surgical treatment for appendicitis

Evolution of two protein kinases may hold key to unlocking highly specific cancer drugs

MIT chemical engineers develop new type of self-healing hydrogel

Georgia State signs license agreement with Cisen to develop compounds for treating cancer

Clinical study comparing effectiveness of three standard treatments for DME published in NEJM

New study turns to epigenetics to look for new therapeutic targets to treat allergic diseases

Scientists identify promising new therapeutic target for prostate cancer

Korean scientists produce flexible, stable monolayers of protein-bound gold nanoparticles

Targeting pericytes and ANG2 signaling may help treat certain breast cancers

InflectraTM (infliximab) patient registry reports interim results in the treatment of inflammatory bowel disease

Scientists develop promising new HIV vaccine agent

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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