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Eminent molecular cell biologist awarded GRC fellowship

The Gutenberg Research College of Johannes Gutenberg University Mainz has awarded the coveted GRC fellowship to Professor Krishnaraj Rajalingam. In the upcoming years, he will lead a research team at the Research Center for Immunotherapy at Mainz University.

26 Nov 2014

Full-day preschool program associated with greater school readiness, achievement

Children who attended a full-day preschool program had higher scores on measures of school readiness skills (language, math, socio-emotional development, and physical health), increased attendance, and reduced chronic absences compared to children who attended part-day preschool, according to a study in the November 26 issue of JAMA.

26 Nov 2014

New hybrid vehicle to improve delivery of DNA vaccines is under development

Described recently in the Proceedings of the National Academy of Sciences, the technology is a biomedical advancement that could help unleash the potential of DNA vaccines, which despite two decades of research, have yet to make a significant impact in the treatment of major illnesses.

26 Nov 2014

Study reveals how one type of DNA damage may lead to several human diseases

Using a new imaging technique, National Institutes of Health researchers have found that the biological machinery that builds DNA can insert molecules into the DNA strand that are damaged as a result of environmental exposures. These damaged molecules trigger cell death that produces some human diseases, according to the researchers.

26 Nov 2014

Dry powdered measles vaccine triggers no adverse side effects in early human testing

A measles vaccine made of fine dry powder and delivered with a puff of air triggered no adverse side effects in early human testing and it is likely effective, according to a paper to be published November 28 in the journal Vaccine.

26 Nov 2014

Research findings could lead to better tests for predicting breast cancer spread

A study combining tumor cells from patients with breast cancer with a laboratory model of blood vessel lining provides the most compelling evidence so far that a specific trio of cells is required for the spread of breast cancer. The findings could lead to better tests for predicting whether a woman's breast cancer will spread and to new anti-cancer therapies.

26 Nov 2014

SNTF protein can predict severity of post-concussion symptoms in professional athletes

New Penn Medicine research has found that elevated levels in the blood of the brain-enriched protein calpain-cleaved αII-spectrin N-terminal fragment, known as SNTF, shortly after sports-related concussion can predict the severity of post-concussion symptoms in professional athletes.

26 Nov 2014

FDA-approved therapy could be effective in older, African American patients with lung cancer

University of Cincinnati researchers have found in a phase-2 clinical trial that a Food and Drug Administration-approved therapy could be effective in treating both older and African American patients with advanced lung cancer who may not be candidates for chemotherapy.

26 Nov 2014

New NIH funding to help researchers develop drug delivery system to prevent HIV infection in women

The University of Texas Medical Branch is part of a collaboration led by the Oak Crest Institute of Science that received a $20 million grant from the National Institutes of Health to develop a novel intravaginal ring capable of delivering powerful antiretroviral drugs to prevent the spread of sexually transmitted HIV in women. The total award to UTMB is approximately $2.5 million.

26 Nov 2014

Taking folic acid supplementation before conception reduces risk of SGA at birth

Taking folic acid before conception significantly reduces the risk of small for gestational age (SGA) at birth, suggests a new study published today (26 November) in BJOG: An International Journal of Obstetrics and Gynaecology.

26 Nov 2014

Study sheds light on how animals regulate body size

The proper regulation of body size is of fundamental importance, but the mechanisms that stop growth are still unclear. In a study now published in the scientific journal eLife, a research group from Instituto Gulbenkian de Ciência (IGC), led by Christen Mirth, shed new light on how animals regulate body size.

26 Nov 2014

Barriers to sharing of public health data hinder decision-making efforts

Barriers to the sharing of public health data hamper decision-making efforts on local, national and global levels, and stymie attempts to contain emerging global health threats, an international team led by the University of Pittsburgh Graduate School of Public Health announced today.

26 Nov 2014

Experimental anti-cancer drugs PF-04691502 and PD-0325901 excel against colorectal cancer models

Genes make proteins and proteins tell your body's cells what to do: one talks to the next, which talks to the next, and to the next. Like a game of telephone, researchers call these "signaling pathways". Abnormalities in these signaling pathways can cause the growth and survival of cancer cells. Commonly, mutations or rearrangements of genes in the MAPK signaling pathway create cancer's fast growth, and alterations in the PI3K signaling pathway allow cancer cells to survive into virtual immortality.

26 Nov 2014

Janssen submits YONDELIS NDA for treatment of advanced soft tissue sarcoma

PharmaMar announces that Janssen Research & Development, LLC has submitted a New Drug Application (NDA) for YONDELIS (trabectedin) to the U.S. Food and Drug Administration for the treatment of patients with advanced soft tissue sarcoma (STS), including liposarcoma and leiomyosarcoma subtypes, who have received prior chemotherapy including an anthracycline.

26 Nov 2014

Decrease in prevalence of VRSA infections in southeastern Michigan

A new study finds a decrease in an emergent strain of methicillin-resistant S. aureus (MRSA) that is resistant to last line defense antibiotics. Researchers examined the prevalence of vancomycin-resistant Staphylococcus aureus (VRSA) infections in southeastern Michigan, where the majority of these infections have occurred in the U.S.

26 Nov 2014

Study: Using wash cloths treated with skin cleanser could reduce skin infections in U.S. jails

New research shows providing detainees wash cloths treated with a skin cleanser could reduce the prevalence of Staphylococcus aureus (S. aureus) bacteria in U.S. jails. Researchers looked at the effect on transmission of S. aureus of using wash cloths treated with chlorhexidine gluconate (CHG) compared with wash cloths with only plain water in detainees at Dallas County Jail.

25 Nov 2014

STAR Analytical Services awarded NIH grant to develop system for hearing-impaired listeners

STAR Analytical Services announces the award of a 3-year $1,500,000 grant from the National Institutes of Health to develop an assistive conversation system for hearing-impaired listeners, including many aging baby-boomers, who have difficulty understanding and participating in conversations in noisy environments.

25 Nov 2014

Automated biospecimen thawing: an interview with Dr Rolf Ehrhardt, CEO of BioCision

Surprisingly, even with decades of cryopreservation research, little progress has been made in the way frozen biospecimens are thawed. It’s still very common for researchers and clinicians to thaw cells and other frozen biological samples in a variety of manual ways ...

25 Nov 2014

Low asthma medication adherence predictors identified in adolescents

Inhaled corticosteroid adherence among adolescents with asthma is low and is associated with a lack of knowledge about treatment and patients’ perceptions about their medicines, show findings of a study published in the Journal of Asthma.

25 Nov 2014

Abnormal vitamin D, trace element levels may indicate asthma risk

Serum levels of vitamin D, copper and zinc could help identify infants with recurrent wheezing who are at risk of developing asthma, Turkish researchers suggest.

25 Nov 2014

Medical News

Eminent molecular cell biologist awarded GRC fellowship

Full-day preschool program associated with greater school readiness, achievement

New hybrid vehicle to improve delivery of DNA vaccines is under development

Study reveals how one type of DNA damage may lead to several human diseases

Dry powdered measles vaccine triggers no adverse side effects in early human testing

Research findings could lead to better tests for predicting breast cancer spread

SNTF protein can predict severity of post-concussion symptoms in professional athletes

FDA-approved therapy could be effective in older, African American patients with lung cancer

New NIH funding to help researchers develop drug delivery system to prevent HIV infection in women

Taking folic acid supplementation before conception reduces risk of SGA at birth

Study sheds light on how animals regulate body size

Barriers to sharing of public health data hinder decision-making efforts

Experimental anti-cancer drugs PF-04691502 and PD-0325901 excel against colorectal cancer models

Janssen submits YONDELIS NDA for treatment of advanced soft tissue sarcoma

Decrease in prevalence of VRSA infections in southeastern Michigan

Study: Using wash cloths treated with skin cleanser could reduce skin infections in U.S. jails

STAR Analytical Services awarded NIH grant to develop system for hearing-impaired listeners

Automated biospecimen thawing: an interview with Dr Rolf Ehrhardt, CEO of BioCision

Low asthma medication adherence predictors identified in adolescents

Abnormal vitamin D, trace element levels may indicate asthma risk

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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