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Blood tests for Chikungunya virus and rheumatoid arthritis could produce similar results

A mosquito-borne virus that has spread to the Caribbean and Central and South America and has caused isolated infections in Florida often causes joint pain and swelling similar to that seen in patients with rheumatoid arthritis.

31 Jan 2015

NCCN commemorates 20 years of advancing high-quality, high-value cancer care

On January 31, 2015, the National Comprehensive Cancer Network celebrates its 20th anniversary. Originally announced as an alliance of 13 leading cancer centers in 1995, NCCN has grown to a network of 25 academic cancer centers; the NCCN mission as an alliance of leading academic cancer centers devoted to patient care, research, and education, is to improve the quality, effectiveness, and efficiency of cancer care so that patients can live better lives.

31 Jan 2015

Multiplexed testing for EGFR and ALK gene rearrangements may be cost-effective for NSCLC treatment

Multiplexed genetic screening for epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) gene rearrangements and subsequent biomarker-guided treatment is cost-effective compared with standard chemotherapy treatment without any molecular testing in the metastatic non-small cell lung cancer (NSCLC) setting in the United States.

31 Jan 2015

FDA’s approval of ibrutinib to treat Waldenstrom's macroglobulinemia receives praises from LLS

The U.S. Food and Drug Administration approval of ibrutinib (Imbruvica) to treat patients with Waldenstrom's macroglobulinemia(WM) is a significant advance for patients with this rare blood cancer.

31 Jan 2015

Scientists reveal mechanism underlying cellular degeneration of upper motor neurons

For the first time, scientists have revealed a mechanism underlying the cellular degeneration of upper motor neurons, a small group of neurons in the brain recently shown to play a major role in ALS pathology.

31 Jan 2015

TCGA researchers uncover differences between tumors with and without HPV infection

The study by The Cancer Genome Atlas (TCGA) researchers analyzed the genomes of 279 head and neck cancer tumors. They identified subtypes of head and neck cancer based on their genomic characteristics, changes in smoking-related tumors, as well as genomic differences in head and neck cancer tumors linked to HPV, the most commonly sexually transmitted disease in the United States.

31 Jan 2015

Rare respiratory virus could be linked to severe neurological illness in children

A cluster of children from Colorado in the USA have been treated for muscle weakness or paralysis that may be connected to a nationwide outbreak of a usually rare respiratory virus called enterovirus D68 (EV-D68), one of more than 100 non-polio enteroviruses.

31 Jan 2015

AbbVie releases Phase 3 results from all-oral OBV/PTV/r treatment for GT1b chronic HCV infection

AbbVie released top-line Phase 3 results for its investigational, all-oral, ribavirin (RBV)-free, two direct-acting antiviral treatment with ombitasvir/paritaprevir/ritonavir (OBV/PTV/r) in patients with genotype 1b (GT1b) chronic hepatitis C virus (HCV) infection in Japan.

31 Jan 2015

Temple University Hospital participating in trial to test vibrating capsule for chronic constipation treatment

Chronic constipation is a common problem that affects approximately 15 percent of the U.S. population, according to the American Gastroenterological Association. It can be painful and lead to a reduction in a patient's quality of life. Temple University Hospital is the only hospital in the Philadelphia region participating in a nationwide clinical trial to test an innovative, vibrating capsule for patients with chronic constipation.

31 Jan 2015

TAU researchers identify novel proteins capable of stymieing growth in antibiotic-resistant bacteria

Antibiotic-resistant infections are on the rise, foiling efforts to reduce death rates in developing countries where uncontrolled use of antibiotics and poor sanitation run amok. The epidemic of "superbugs," bacteria resistant to antibiotics, knows no borders -- presenting a clear and present danger around the globe.

31 Jan 2015

NSF awards grant for study on user-centered design framework for powered lower-extremity exoskeletons

It wasn't too long ago that the idea of a wearable robot that would lend its user increased mobility and strength seemed like the stuff of science fiction; indeed, films like Aliens and Iron Man, which featured characters wearing powered exoskeletons, incited the imaginations of many.

31 Jan 2015

Micromotor fueled by stomach acid effectively delivers gold nanoparticles

Researchers at the University of California, San Diego have shown that a micromotor fueled by stomach acid can take a bubble-powered ride inside a mouse. These tiny motors, each about one-fifth the width of a human hair, may someday offer a safer and more efficient way to deliver drugs or diagnose tumors.

31 Jan 2015

New insight on how naturally occurring mutations can be introduced into DNA

Scientists have shed light on how naturally occurring mutations can be introduced into our DNA.

31 Jan 2015

Cell-penetrating nanoparticles can efficiently transport oligonucleotide drugs into cells

Therapeutic oligonucleotide analogs represent a new and promising family of drugs that act on nucleic acid targets such as RNA or DNA; however, their effectiveness has been limited due to difficulty crossing the cell membrane.

31 Jan 2015

Researchers identify molecular mechanisms that can prevent blindness, promote recovery from stroke

Research led by Nicolas Bazan, MD, PhD, Boyd Professor, Ernest C. and Yvette C. Villere Chair of Retinal Degeneration Research, and Director of the Neuroscience Center of Excellence at LSU Health New Orleans, has discovered gene interactions that determine whether cells live or die in such conditions as age-related macular degeneration and ischemic stroke.

31 Jan 2015

Researchers review positive and negative effects of mobile, interactive media use by children

Mobile devices are everywhere and children are using them more frequently at young ages. The impact these mobile devices are having on the development and behavior of children is still relatively unknown. In a commentary in the journal Pediatrics, researchers review the many types of interactive media available today and raise important questions regarding their use as educational tools, as well as their potential detrimental role in stunting the development of important tools for self-regulation.

31 Jan 2015

Breast and lung cancer patients with low levels of TTP protein have poorer prognosis

Moffitt Cancer Center researchers have found that breast and lung cancer patients who have low levels of a protein called tristetraprolin (TTP) have more aggressive tumors and a poorer prognosis than those with high levels of the protein.

31 Jan 2015

Pancreatic cancer cells know a way to sidestep chemotherapy, reveal Fox Chase researchers

Pancreatic cancer is one of the deadliest forms of the disease. The American Cancer Society's most recent estimates for 2014 show that over 46,000 people will be diagnosed with pancreatic cancer and more than 39,000 will die from it. Now, research led by Timothy J. Yen, PhD, Professor at Fox Chase Cancer Center, reveals that one reason this deadly form of cancer can be so challenging to treat is because its cells have found a way to sidestep chemotherapy.

30 Jan 2015

Scientists identify strong link between beclin 1 gene and triple-negative breast cancer

UT Southwestern Medical Center scientists have identified a strong link between the most aggressive type of breast cancer and a gene that regulates the body's natural cellular recycling process, called autophagy.

30 Jan 2015

Lifestyle tips to lower heart disease risks

With the arrival of American Heart Month in February, it's that time of the year to remind ourselves to take good care of our hearts.

30 Jan 2015

Medical News

Blood tests for Chikungunya virus and rheumatoid arthritis could produce similar results

NCCN commemorates 20 years of advancing high-quality, high-value cancer care

Multiplexed testing for EGFR and ALK gene rearrangements may be cost-effective for NSCLC treatment

FDA’s approval of ibrutinib to treat Waldenstrom's macroglobulinemia receives praises from LLS

Scientists reveal mechanism underlying cellular degeneration of upper motor neurons

TCGA researchers uncover differences between tumors with and without HPV infection

Rare respiratory virus could be linked to severe neurological illness in children

AbbVie releases Phase 3 results from all-oral OBV/PTV/r treatment for GT1b chronic HCV infection

Temple University Hospital participating in trial to test vibrating capsule for chronic constipation treatment

TAU researchers identify novel proteins capable of stymieing growth in antibiotic-resistant bacteria

NSF awards grant for study on user-centered design framework for powered lower-extremity exoskeletons

Micromotor fueled by stomach acid effectively delivers gold nanoparticles

New insight on how naturally occurring mutations can be introduced into DNA

Cell-penetrating nanoparticles can efficiently transport oligonucleotide drugs into cells

Researchers identify molecular mechanisms that can prevent blindness, promote recovery from stroke

Researchers review positive and negative effects of mobile, interactive media use by children

Breast and lung cancer patients with low levels of TTP protein have poorer prognosis

Pancreatic cancer cells know a way to sidestep chemotherapy, reveal Fox Chase researchers

Scientists identify strong link between beclin 1 gene and triple-negative breast cancer

Lifestyle tips to lower heart disease risks

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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