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Scientists demonstrate technique for editing genome in sperm-producing adult stem cells

Scientists at Indiana University and colleagues at Stanford and the University of Texas have demonstrated a technique for "editing" the genome in sperm-producing adult stem cells, a result with powerful potential for basic research and for gene therapy.

16 Dec 2014

Novartis announces FDA approval of Signifor LAR for treatment of patients with acromegaly

Novartis announced today that the US Food and Drug Administration has approved Signifor long-acting release (LAR) (pasireotide) for injectable suspension, for intramuscular use, for the treatment of patients with acromegaly who have had an inadequate response to surgery and/or for whom surgery is not an option.

16 Dec 2014

Roche announces launch of cobas Liat System for on-demand testing in different settings

Roche today announced the launch of the cobas Liat System—a fast, compact , easy to use, molecular diagnostic platform, designed for on-demand testing in physician clinics, pharmacies and hospital lab settings.

16 Dec 2014

New MIT study implicates RNA-binding proteins in regulation of cancer

A new study from MIT implicates a family of RNA-binding proteins in the regulation of cancer, particularly in a subtype of breast cancer. These proteins, known as Musashi proteins, can force cells into a state associated with increased proliferation.

16 Dec 2014

Clinatec chairman receives Lifetime Achievement Award for breakthrough research on Parkinson's disease

Prof. Alim-Louis Benabid, board chairman of Clinatec - The Edmond J. Safra Biomedical Research Center, received the Lifetime Achievement award on Dec. 13 from the North American Neuromodulation Society (NANS) for his work in developing deep brain stimulation to relieve symptoms in Parkinson’s disease patients.

16 Dec 2014

NICE recommends REMICADE, HUMIRA and SIMPONI therapies for patients with ulcerative colitis

The National Institute for Health and Care Excellence (NICE) has issued its Final Appraisal Document (FAD) recommending REMICADE (infliximab), HUMIRA (adalimumab) and SIMPONI (golimumab), within their marketing authorisations, as options for treating moderately to severely active ulcerative colitis (UC) in adults whose disease has responded inadequately to conventional therapy including corticosteroids and mercaptopurine or azathioprine, or who cannot tolerate, or have medical contraindications for, such therapies.

16 Dec 2014

Sophia Genetics earns ISO 13485 and ISO 27001 certification for safe data handling and security

Sophia Genetics, the European leader in Clinical Genomics and Next Generation DNA Sequencing (NGS), has become the first company to achieve both ISO 13485 and ISO 27001 certification for its commitment to safe data handling and security.

16 Dec 2014

Study provides rare evidence on effect of Iraq War on child marriage, early childbearing

A study published today is the first detailed assessment of whether the 8-year Iraq War had an effect on childbearing. The study found that before the war, from 1997 to 2003, adolescent fertility in Iraq was stable at just below 70 births per 1,000 girls aged 15-19.

16 Dec 2014

Leicester biologist examines zebrafish to understand pathological aggression

An international research consortium, including a biologist from Leicester, has heard that aggression in young male prisoners can be reduced by treating ADHD.

16 Dec 2014

Trastuzumab drug improves long-term survival of patients with HER-2 positive breast cancer

VCU Massey Cancer Center physician-researcher Charles E. Geyer, Jr., M.D., was the National Protocol Officer for one component of a large national study involving two National Cancer Institute-supported clinical trials that demonstrated that trastuzumab significantly improves the long-term survival of HER-2 positive breast cancer patients.

16 Dec 2014

Researchers map B cell response to non-gluten proteins of wheat in celiac disease

Researchers at Columbia University Medical Center have found that, in addition to gluten, the immune systems of patients with celiac disease react to specific types of non-gluten protein in wheat. The results were reported online in the Journal of Proteome Research.

16 Dec 2014

Novasep expands presence in South East Asia with opening of new office in Thailand

Novasep, a leading supplier of manufacturing solutions to the life sciences industry, today announces that it is expanding its presence in South East Asia with the opening of an office in Bangkok, Thailand.

16 Dec 2014

Researchers use functional MRI to understand how the brain functions

University of Nevada, Reno neuroscientists are working with Renown Health to bring new research capabilities to northern Nevada. The research group, led by University Professor of Psychology Michael Webster, has purchased equipment that augments the existing 3T magnetic resonance imaging (MRI) technology at Renown Health for studies of human brain function.

16 Dec 2014

Murdoch University outlines research on antimicrobial resistance at symposium

Murdoch University profiled its strong teaching and research focus around a One Health agenda at a symposium on a looming public health issue, antimicrobial resistance (AMR), on December 8.

16 Dec 2014

ADHD, conduct disorder in young adolescents linked to increased alcohol and tobacco use

A new study links ADHD and conduct disorder in young adolescents with increased alcohol and tobacco use. The Cincinnati Children's Hospital Medical Center study is among the first to assess such an association in this age group.

15 Dec 2014

FL118 agent shows efficacy as personalized, targeted therapy for certain cancer tumors

A team led by Fengzhi Li, PhD, and Xinjiang Wang, PhD, of Roswell Park Cancer Institute has reported new findings regarding therapeutic targets of the novel anticancer agent FL118. Previous studies from these researchers have showed that FL118 induces cancer cell death, or apoptosis, by inhibiting expression of multiple cell-survival proteins (survivin, Mcl-1, XIAP or cIAP2).

15 Dec 2014

Two-drug combination before surgery benefits women with triple-negative breast cancer

A breast cancer specialist and clinical researcher at Women & Infants Hospital of Rhode Island presented research yesterday at the 2014 San Antonio Breast Cancer Symposium showing that adding either the chemotherapy drug carboplatin or the blood vessel-targeting drug bevacizumab to the standard treatment of chemotherapy before surgery helped women who have the basal-like subtype of triple-negative breast cancer.

15 Dec 2014

Novel marker may help doctors choose most effective treatment for older patients with AML

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute describes a novel marker that might help doctors choose the least toxic, most effective treatment for many older patients with acute myeloid leukemia (AML).

15 Dec 2014

Molecular signaling pathways in the gut influence NAFLD

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder and affects approximately 1 billion people worldwide. It is not clear how this disease develops, but recent studies suggest that the bacterial population in the gut influences NAFLD.

15 Dec 2014

Heroin use impacts HIV disease progression

Researchers at Yale and Boston University and their Russian collaborators have found that occasional heroin use by HIV-positive patients may be particularly harmful to the immune system and worsens HIV disease, compared to persistent or no heroin use.

15 Dec 2014

Medical News

Scientists demonstrate technique for editing genome in sperm-producing adult stem cells

Novartis announces FDA approval of Signifor LAR for treatment of patients with acromegaly

Roche announces launch of cobas Liat System for on-demand testing in different settings

New MIT study implicates RNA-binding proteins in regulation of cancer

Clinatec chairman receives Lifetime Achievement Award for breakthrough research on Parkinson's disease

NICE recommends REMICADE, HUMIRA and SIMPONI therapies for patients with ulcerative colitis

Sophia Genetics earns ISO 13485 and ISO 27001 certification for safe data handling and security

Study provides rare evidence on effect of Iraq War on child marriage, early childbearing

Leicester biologist examines zebrafish to understand pathological aggression

Trastuzumab drug improves long-term survival of patients with HER-2 positive breast cancer

Researchers map B cell response to non-gluten proteins of wheat in celiac disease

Novasep expands presence in South East Asia with opening of new office in Thailand

Researchers use functional MRI to understand how the brain functions

Murdoch University outlines research on antimicrobial resistance at symposium

ADHD, conduct disorder in young adolescents linked to increased alcohol and tobacco use

FL118 agent shows efficacy as personalized, targeted therapy for certain cancer tumors

Two-drug combination before surgery benefits women with triple-negative breast cancer

Novel marker may help doctors choose most effective treatment for older patients with AML

Molecular signaling pathways in the gut influence NAFLD

Heroin use impacts HIV disease progression

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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