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CWRU researchers find mechanism that enables LRAT enzyme to store vitamin A

Researchers at Case Western Reserve University School of Medicine have uncovered the mechanism that enables the enzyme Lecithin: retinol acyltransferase (LRAT) to store vitamin A — a process that is indispensable for vision.

12 Dec 2014

Survey: Social care workers experience difficulties with interview process

Workers in the social care sector are experiencing a number of difficulties with the interview process, according to a survey carried out by specialist recruiter Randstad Care.

12 Dec 2014

BGI Diagnostics develops ‘education hub’ to raise awareness about non-invasive prenatal testing

provider of accurate, reliable and affordable genetic tests and molecular diagnostics services has demonstrated its commitment to raising awareness about non-invasive prenatal testing (NIPT) by developing a dedicated ‘education hub’ as part of its new, highly informative website.

12 Dec 2014

Key steps to improve care for pregnant mothers and babies affected by CDH

A new study has revealed key steps for hospitals to improve care for pregnant mums and babies affected by a life-threatening condition.

12 Dec 2014

Brunel scientists find way to target hard-to-reach cancers using 'Trojan horse' nanoparticles

Scientists at Brunel University London have found a way of targeting hard-to-reach cancers and degenerative diseases using nanoparticles, but without causing the damaging side effects the treatment normally brings.

12 Dec 2014

Exudation-free period key to cataract surgery success in AMD

Cataract surgery can benefit patients with exudative age-related macular degeneration previously treated with anti-vascular endothelial growth factors if they have been treated and are exudation-free for more than 12 months, study findings indicate.

11 Dec 2014

Caution advised over OCT measurement of thick choroid

Enhanced depth imaging optical coherence tomography is consistent for measuring choroidal thickness, researchers confirm, but its accuracy may be impaired in eyes with a very thick choroid.

11 Dec 2014

Optical coherence tomography methods comparable for AMD assessments

There is good accordance between spectral-domain and time-domain optical coherence tomography image assessments of eyes treated for neovascular age-related macular degeneration, show study findings.

11 Dec 2014

OCT enhances neovascular subtype detection in AMD

Researchers recommend the inclusion of optical coherence tomography anatomic classification with fluorescein angiography grading to identify initial neovascular lesion subtypes in newly diagnosed age-related macular degeneration.

11 Dec 2014

Psychotic experiences show shared genetic liability

Study findings provide support for psychotic experiences being an early marker of increased risk of psychosis transition and an important intermediary phenotype in transdiagnostic research on psychosis.

11 Dec 2014

First-line dacomitinib may improve advanced NSCLC survival

Preliminary research suggests that the second-generation tyrosine kinase inhibitor dacomitinib may improve progression-free survival in patients with advanced non-small-cell lung cancer with epidermal growth factor receptor mutations.

11 Dec 2014

Non-use of bipolar medication typically follows careful ‘risk–benefit’ evaluation

An investigation into why and how patients with bipolar disorder manage their moods without medication has found that most individuals are initially motivated by concerns about side effects.

11 Dec 2014

Addition of S-1 to cisplatin plus radiotherapy ‘favourable’ in NSCLC

Research suggests that treatment with cisplatin plus S-1 together with thoracic radiotherapy is relatively efficacious and tolerable in patients with locally advanced non-small-cell lung cancer.

11 Dec 2014

Study: Drive for energy efficient homes could raise asthma risks

The drive for energy efficient homes could increase asthma risks, according to new research.

11 Dec 2014

Riding roller coasters can trigger stroke in children

Riding a couple roller coasters at an amusement park appears to have triggered an unusual stroke in a 4-year-old boy, according to a report in the journal Pediatric Neurology.

11 Dec 2014

Claritas, NextCODE Health partner to bring global leadership in pediatric medicine, sequence analysis

To rapidly expand the use and power of genomic sequencing for diagnosing and treating rare diseases, Claritas Genomics and NextCODE Health today announced a strategic partnership bringing together global leadership in pediatric medicine and sequence analysis. Claritas Genomics, affiliated with Boston Children's Hospital, is a CLIA-certified clinical laboratory serving the DNA-based diagnostic testing needs of children's hospitals that admit hundreds of thousands of patients with genetic disorders every year.

11 Dec 2014

OncoTherapy Network discusses latest research on prostate cancer

UBM Medica US announces that OncoTherapy Network, a leading online community to help oncologists and other clinicians gain a better understanding of the newest information available regarding the use of targeted therapies and immunotherapies, discusses some of the latest research on prostate cancer.

11 Dec 2014

GI Partners completes acquisition of 9911 Belward Campus Drive

GI Partners today announced that it has completed the acquisition of 9911 Belward Campus Drive located in Rockville, Maryland. The acquisition was made through TechCore, LLC, which is a $1 billion discretionary core real estate fund managed by GI Partners.

11 Dec 2014

Diplomat announces new partnership with Novation through Hospital Specialty Rx Program

Diplomat, the nation's largest independent specialty pharmacy, has announced a new partnership with Novation through their Hospital Specialty Rx Program.

11 Dec 2014

FDA clears ArmaGen's AGT-182 IND application for treatment of Hunter syndrome

ArmaGen, Inc., a privately held biotechnology company focused on developing novel therapies to treat severe neurological disorders, announced today that the Investigational New Drug (IND) application for the company's lead product candidate, AGT-182 for the treatment of Hunter syndrome, has been accepted by the U.S. Food and Drug Administration and is now active.

11 Dec 2014