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Cigarette smoking continues to cause nearly three in ten cancer deaths in the U.S.

A new American Cancer Society study finds that despite significant drops in smoking rates, cigarettes continue to cause about three in ten cancer deaths in the United States. The study, appearing in the Annals of Epidemiology, concludes that efforts to reduce smoking prevalence as rapidly as possible should be a top priority for the U.S. public health efforts to prevent cancer deaths.

10 Dec 2014

Treatment guidelines lacking for Ebola patients, say infectious diseases experts

As the Ebola Virus Diseases (EVD) epidemic continues to rage in West Africa, infectious diseases experts call attention to the striking lack of treatment guidelines. With over 16,000 total cases and more than 500 new infections reported per week, and probable underreporting of both cases and fatalities, the medical community still does not have specific approved treatment in place for Ebola, according to an editorial published in the International Journal of Infectious Diseases.

10 Dec 2014

New guide documents threat endocrine-disrupting chemicals pose to human health

As governments, industry and public interest groups from across the globe prepare to meet next week to discuss endocrine-disrupting chemicals and other international chemical safety issues, the Endocrine Society and IPEN released a new guide documenting the threat endocrine-disrupting chemicals (EDCs) pose to human health.

10 Dec 2014

Chemical chaperone: A new therapeutic option for epilepsy

Researchers found out that the conformational defect in a specific protein causes Autosomal Dominant Lateral Temporal Lobe Epilepsy (ADLTE) which is a form of familial epilepsy. They showed that treatment with chemical corrector called "chemical chaperone" ameliorates increased seizure susceptibility in a mouse model of human epilepsy by correcting the conformational defect.

10 Dec 2014

Bayer, DNDi sign first agreement to develop new oral treatment for onchocerciasis

Bayer HealthCare and the Drugs for Neglected Diseases initiative (DNDi) have signed an agreement under which Bayer will provide the active ingredient emodepside to support DNDi in its effort to develop a new oral drug to treat river blindness (or onchocerciasis). The world's second leading infectious cause of blindness, river blindness is a neglected tropical disease caused by a filarial worm.

10 Dec 2014

Targeted therapy with radiopharmaceuticals has great potential for cancer treatment

Cancer therapy can be much more effective using a new way to customize nuclear medicine treatment, researchers say in the December 2014 issue of The Journal of Nuclear Medicine. The process could also be useful for other diseases that could benefit from targeted radiation.

10 Dec 2014

Advances in fight against TB, sudden cardiac death

Research projects into two of the biggest killers in worldwide health, tuberculosis and sudden cardiac death, will be the subjects of the University of Leicester Graduate School Doctoral Inaugural Lectures, delivered by two of the winners of this year's PhD prizes in the College of Medicine, Biological Sciences and Engineering.

10 Dec 2014

Laughing gas could be used as treatment for severe depression

Nitrous oxide, or laughing gas, has shown early promise as a potential treatment for severe depression in patients whose symptoms don't respond to standard therapies. The pilot study, at Washington University School of Medicine in St. Louis, is believed to be the first research in which patients with depression were given laughing gas.

10 Dec 2014

Learning technique may help overcome cognitive issues in fragile X syndrome

A learning technique that maximizes the brain's ability to make and store memories may help overcome cognitive issues seen in fragile X syndrome, a leading form of intellectual disability, according to UC Irvine neurobiologists.

10 Dec 2014

ADHD, conduct disorder increase alcohol and tobacco use in young adolescents

A new study links ADHD and conduct disorder in young adolescents with increased alcohol and tobacco use. The Cincinnati Children's Hospital Medical Center study is among the first to assess such an association in this age group.

10 Dec 2014

Southern Regional Education Board honors UTSA professor as Mentor of the Year

Edwin Barea-Rodriguez, professor and chair of the UTSA Department of Biology, was recently honored as the Mentor of the Year by the Southern Regional Education Board at a conference in Atlanta. More than 1,300 attended the conference, where the nation's largest gathering of minority doctoral scholars discussed issues facing new and aspiring faculty members.

10 Dec 2014

Study: Simeprevir-based therapy proves effective in treating chronic HCV infection

Researchers at Penn Medicine, in collaboration with a multi-center international team, have shown that a protease inhibitor, simeprevir, a once a day pill, along with interferon and ribavirin has proven as effective in treating chronic Hepatitis C virus infection (HCV) as telaprevir with interferon and ribavirin, the standard of care in developing countries.

10 Dec 2014

Immunizing school-aged children from flu can protect others as well

Mathematical models predicted it, and now a University of Florida study confirms it: Immunizing school-aged children from flu can protect other segments of the population, as well.

10 Dec 2014

University of Illinois study could provide insight into protein-misfolding diseases

When a large protein unfolds in transit through a cell, it slows down and can get stuck in traffic. Using a specialized microscope -- a sort of cellular traffic camera -- University of Illinois chemists now can watch the way the unfolded protein diffuses.

10 Dec 2014

Drug proves effective at inhibiting growth of drug-resistant bacteria

A treatment pioneered at the University of Pittsburgh Center for Vaccine Research is far more effective than traditional antibiotics at inhibiting the growth of drug-resistant bacteria, including so-called "superbugs" resistant to almost all existing antibiotics, which plague hospitals and nursing homes.

10 Dec 2014

Bed nets alone are enough to protect against malaria, study suggests

The combined use of spraying insecticide inside homes and insecticide-treated bed nets is no better at protecting children against malaria than using bed nets alone, a study in The Gambia suggests. The findings, published in The Lancet, should encourage donors to invest their limited resources in additional bed nets, the more cost-effective solution to tackling malaria.

10 Dec 2014

Epizyme's PRMT5 inhibitor shows efficacy in pre-clinical models of mantle cell lymphoma

Epizyme, Inc., a clinical stage biopharmaceutical company creating innovative personalized therapeutics for patients with genetically defined cancers, announced today the results from a preclinical study showing in vitro and in vivo activity of its first-in-class PRMT5 inhibitor EPZ015666 in mantle cell lymphoma (MCL), an aggressive form of non-Hodgkin lymphoma (NHL).

10 Dec 2014

Epizyme presents EPZ-5676 Phase 1 trial results for acute leukemia at ASH 2014

Epizyme, Inc., a clinical stage biopharmaceutical company creating innovative personalized therapeutics for patients with genetically defined cancers, announced today the presentation of results from the company’s Phase 1 trial of EPZ-5676, a potent and selective inhibitor of the DOT1L histone methyltransferase (HMT).

10 Dec 2014

Scientists identify brain mechanism that drives our appetite for glucose-rich foods

Scientists have discovered a mechanism in the brain that may drive our appetite for foods rich in glucose and could lead to improved treatments for obesity.

10 Dec 2014

Molecular response criteria examined for CML

The limitations in determining molecular response in patients with chronic myeloid leukaemia treated with tyrosine kinase inhibitor therapy have been reviewed in Cancer.

9 Dec 2014

Medical News

Cigarette smoking continues to cause nearly three in ten cancer deaths in the U.S.

Treatment guidelines lacking for Ebola patients, say infectious diseases experts

New guide documents threat endocrine-disrupting chemicals pose to human health

Chemical chaperone: A new therapeutic option for epilepsy

Bayer, DNDi sign first agreement to develop new oral treatment for onchocerciasis

Targeted therapy with radiopharmaceuticals has great potential for cancer treatment

Advances in fight against TB, sudden cardiac death

Laughing gas could be used as treatment for severe depression

Learning technique may help overcome cognitive issues in fragile X syndrome

ADHD, conduct disorder increase alcohol and tobacco use in young adolescents

Southern Regional Education Board honors UTSA professor as Mentor of the Year

Study: Simeprevir-based therapy proves effective in treating chronic HCV infection

Immunizing school-aged children from flu can protect others as well

University of Illinois study could provide insight into protein-misfolding diseases

Drug proves effective at inhibiting growth of drug-resistant bacteria

Bed nets alone are enough to protect against malaria, study suggests

Epizyme's PRMT5 inhibitor shows efficacy in pre-clinical models of mantle cell lymphoma

Epizyme presents EPZ-5676 Phase 1 trial results for acute leukemia at ASH 2014

Scientists identify brain mechanism that drives our appetite for glucose-rich foods

Molecular response criteria examined for CML

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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