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Phase 2 RESONATE-17 study: IMBRUVICA (ibrutinib) improves survival in CLL patients with del 17p

Results from the Phase 2 RESONATE-17 (PCYC-1117) study show IMBRUVICA (ibrutinib) was associated with an 82.6 percent investigator-assessed overall response rate (ORR; the primary endpoint) and a 79 percent progression-free survival (PFS) rate at 12 months in people living with relapsed/refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have a genetic mutation known as deletion 17p (del 17p).

9 Dec 2014

Nationwide Children's Hospital receives ANCC Magnet Recognition for third time

The American Nurses Credentialing Center's Magnet Recognition Program for excellence in nursing services has granted Nationwide Children's Hospital ANCC Magnet Recognition for a third time. This prestigious recognition is the ultimate benchmark in nursing excellence and is awarded to only about seven percent of the nation's more than 6,000 hospitals across the country.

8 Dec 2014

PRM-151 compound shows positive results for treating advanced myelofibrosis

A study that investigated the potential of the compound PRM-151 (PRM) for reducing progressive bone marrow fibrosis (scarring) in patients with advanced myelofibrosis has shown initial positive results. Myelofibrosis is a life-threatening bone marrow cancer.

8 Dec 2014

UTHealth receives $7.3 million grant to research on health information technology

The University of Texas Health Science Center at Houston School of Biomedical Informatics has been awarded grants totaling $7.3 million to enhance health care and biomedical discovery through the use of health information technology.

8 Dec 2014

McMaster University researchers identify hormone that contributes to obesity, diabetes

Researchers from McMaster University have identified an important hormone that is elevated in obese people and contributes to obesity and diabetes by inhibiting brown fat activity.

8 Dec 2014

Screening system spots cancerous changes invisible to sequencing

A technique that can identify causes of cancer invisible to genetic sequencing has uncovered large sets of previously unknown pancreatic cancer genes. It is hoped that this study will boost research into a disease that is still poorly understood and for which five-year survival rates have stood at around 5 per cent for the past four decades.

8 Dec 2014

Findings open new avenues for research to predict risk of therapy-related AML

For a small percentage of cancer patients, treatment aimed at curing the disease leads to a form of leukemia with a poor prognosis. Conventional thinking goes that chemotherapy and radiation therapy induce a barrage of damaging genetic mutations that kill cancer cells yet inadvertently spur the development of acute myeloid leukemia (AML), a blood cancer.

8 Dec 2014

Elsevier launches Journal of Vascular Surgery Cases

Elsevier, a world-leading provider of scientific, technical, and medical information products and services, announced today the launch of Journal of Vascular Surgery Cases, a new open access, online-only journal dedicated to publishing peer-reviewed, high quality case reports related to all aspects of arterial, venous, and lymphatic diseases, including the placement and maintenance of arterio-venous dialysis access, with an emphasis on the practicing clinician.

8 Dec 2014

Study highlights causes of postpartum disorders in new mothers

In the days shortly after giving birth, most mothers experience a period of increased calmness and decreased stress responses, but around 20% of mothers experience anxiety. Some women may become depressed, and around one in a thousand can develop psychosis. The latest evidence indicates that these distressing responses to motherhood are still poorly understood, but that animal research could provide valuable clues to their causes.

8 Dec 2014

Rutgers researcher receives NIH grant to develop rapid test to diagnose Ebola

Rutgers researcher David Alland, working with the California biotechnology company Cepheid, has received a grant of nearly $640,000 from the National Institutes of Health to develop a rapid test to diagnose Ebola as well as other viruses that can cause symptoms similar to Ebola.

8 Dec 2014

Low doses of fluoxetine could hold key to preventing PMS symptoms

Low doses of fluoxetine - better known as the anti-depressant Prozac - could hold the key to preventing PMS symptoms, an international team of researchers has found.

8 Dec 2014

Studies presented at ASH meeting compare new, standard-of-care treatments for blood clots

Studies presented at the 56th American Society of Hematology Annual Meeting and Exposition compare new and standard-of-care treatments for blood clots and further illuminate clot risks in vulnerable populations, such as cancer patients.

8 Dec 2014

New article describes current state of asbestos use worldwide

Challenges to global health can evolve from policies and decisions that take years or decades to unfold. An article in the current issue of the Annals of Global Health describes the current state of asbestos use worldwide, a story that began over 100 years ago, and the real and contrived controversies regarding asbestos.

8 Dec 2014

Older Latinos living in safe, walkable neighborhoods less likely to develop severe depressive symptoms

Older Latinos living in the U.S. who perceive their neighborhoods as safer and more walkable are less likely to develop severe depressive symptoms, and the effect may be long term, a new study suggests.

8 Dec 2014

UC Berkeley study finds self-worth key to diagnoses of psychopathologies

Donald Trump's ego may be the size of his financial empire, but that doesn't mean he's the picture of mental health. The same can be said about the self-esteem of people who are living from paycheck to paycheck, or unemployed. New research from the University of California, Berkeley, underscores this mind-wallet connection.

8 Dec 2014

Cellular mechanisms of alcohol dependence: an interview with Dr Sanna, TSRI

In the brain there are both excitatory and inhibitory neurotransmitters. These are molecules that are released from nerve endings in the brain and in the periphery and either excite or inhibit other nerve cells, also known as neurons.

8 Dec 2014

Spark Therapeutics, Pfizer partner to develop SPK-FIX for potential treatment of hemophilia B

Spark Therapeutics, a late-stage gene therapy company developing treatments for debilitating genetic diseases, announced today that it has entered into a global collaboration with Pfizer Inc. for the development and potential commercialization of SPK-FIX, a development program advancing proprietary, bio-engineered adeno-associated virus (AAV) vectors for the potential treatment of hemophilia B.

8 Dec 2014

Henry Ford Hospital recruits patients to participate in brain cancer clinical trial

Henry Ford Hospital today announced that it is actively recruiting patients to participate in a clinical trial taking place at the Hermelin Brain Tumor Center which is showing promising results in patients with brain cancer.

8 Dec 2014

Verizon announces winners of 2014 Powerful Answers Award

The wait is over. Verizon is proud to announce the winners of Verizon's 2014 Powerful Answers Award, three in each of the following categories: education, health care, sustainability and transportation.

8 Dec 2014

New kind of knee surgery provides much needed relief for patients

A new kind of knee surgery is providing much needed relief for patients in the greater Houston area. For many years, anterior cruciate ligament (ACL) reconstructions have been frequently performed to correct instability in the knee, however many patients never return to their pre-injury level of activity following surgery. That is changing, says orthopaedic surgeon Dr. William Hayes, because surgeons are now addressing injuries to the anterolateral ligament (ALL) in the knee as well.

8 Dec 2014

Medical News

Phase 2 RESONATE-17 study: IMBRUVICA (ibrutinib) improves survival in CLL patients with del 17p

Nationwide Children's Hospital receives ANCC Magnet Recognition for third time

PRM-151 compound shows positive results for treating advanced myelofibrosis

UTHealth receives $7.3 million grant to research on health information technology

McMaster University researchers identify hormone that contributes to obesity, diabetes

Screening system spots cancerous changes invisible to sequencing

Findings open new avenues for research to predict risk of therapy-related AML

Elsevier launches Journal of Vascular Surgery Cases

Study highlights causes of postpartum disorders in new mothers

Rutgers researcher receives NIH grant to develop rapid test to diagnose Ebola

Low doses of fluoxetine could hold key to preventing PMS symptoms

Studies presented at ASH meeting compare new, standard-of-care treatments for blood clots

New article describes current state of asbestos use worldwide

Older Latinos living in safe, walkable neighborhoods less likely to develop severe depressive symptoms

UC Berkeley study finds self-worth key to diagnoses of psychopathologies

Cellular mechanisms of alcohol dependence: an interview with Dr Sanna, TSRI

Spark Therapeutics, Pfizer partner to develop SPK-FIX for potential treatment of hemophilia B

Henry Ford Hospital recruits patients to participate in brain cancer clinical trial

Verizon announces winners of 2014 Powerful Answers Award

New kind of knee surgery provides much needed relief for patients

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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