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MedImmune initiates MEDI8897 phase I clinical studies for treatment of RSV infections

AIMM Therapeutics, a leading human therapeutic antibody company, today announced that its partner MedImmune, LLC, the global biologics unit of AstraZeneca, has initiated phase I clinical studies with MEDI8897, a best-in-class antibody for the treatment of respiratory syncytial virus (RSV) infections in young, at risk children.

2 Jul 2014

Study explores neurological outcomes in patients treated for traumatic brain injury

In patients with a traumatic brain injury (TBI), neither the administration of the hormone erythropoietin (EPO) or maintaining a higher hemoglobin concentration through blood transfusion resulted in improved neurological outcome at 6 months, according to a study in the July 2 issue of JAMA.

2 Jul 2014

Ipsen seeks marketing authorization from FDA for Somatuline Depot 120mg injection

Ipsen Biopharmaceuticals, Inc., the U.S. affiliate of Ipsen today announced that it has submitted a Supplemental New Drug Application to the U.S. Food and Drug Administration for Somatuline Depot 120mg injection for the treatment of gastroenteropancreatic neuroendocrine tumors (GEP-NETs).

2 Jul 2014

Patient Protection and Affordable Care Act can improve health of the US population

The Patient Protection and Affordable Care Act, signed into law by US President Barack Obama in 2010, can advance public health in the USA by supporting increased emphasis on prevention, and reversing the historic division between public health and private health care services, according to the authors of new research published in The Lancet as part of a new Series, The health of Americans.

2 Jul 2014

USA witnesses dramatic slowdown in health spending growth over last decade

Growth in health expenditure in the USA slowed dramatically between 2000 and 2011, bringing the growth rate of the country’s health budget in line with other high-spending countries, according to new research published in The Lancet as part of a new Series, The health of Americans.

2 Jul 2014

New gene therapy for Acute Intermittent Porphyria

Angeles suffers from a severe and rare genetic disease called Acute Intermittent Porphyria (AIP). This means, one of her genes restrains her liver to produce a specific protein needed for the metabolism of the blood. During an AIP attack Angeles usually feels intense abdominal pain, and her mental status changes. Women live at an increased risk to trigger the symptoms, because porphyria is related to the menstrual cycle.

2 Jul 2014

Research on inflammasomes lays foundations for developing new RA treatments

Patients with more or less severe forms of rheumatoid arthritis (RA) may have the same painful symptoms, but does this mean that the cause of their illness is the same? And therefore that they should all receive the same treatment? Scientists at VIB and Ghent University have demonstrated with their research into inflammasomes that RA should be considered as a syndrome rather than a single disease.

2 Jul 2014

Australian immunologists uncover additional role for antibody-making 'B cells'

A discovery by Australian immunologists, uncovering an additional role for antibody-making 'B cells', is considered important enough by the American Association of Immunologists to rank it among the top 10% of articles in the latest issue of The Journal of Immunology, off the press today.

2 Jul 2014

Study results may help prevent eye injuries among soldiers

Researchers at The University of Texas at San Antonio are discovering that the current protective eyewear used by our U.S. armed forces might not be adequate to protect soldiers exposed to explosive blasts.

2 Jul 2014

Eurofins Genomics, AmpTec sign co-marketing agreement for IVT-RNAs

Eurofins Genomics, international market leader in genomic services, and AmpTec, internationally recognized provider of RNA technology products, have agreed on non-exclusively co-marketing AmpTec's IVT-RNAs globally.

2 Jul 2014

Sugar-coated cells are potentially deadly for cancer patients

Every living cell's surface has a protein-embedded membrane that's covered in polysaccharide chains - a literal sugar coating. A new study by a Cornell University researcher found this coating is especially thick and pronounced on cancer cells and is a crucial determinant of the cell's survival.

2 Jul 2014

Exome sequencing improves diagnosis of mitochondrial disease

Use of exome sequencing improved the ability to identify the underlying gene mutations in patients with biochemically defined defects affecting multiple mitochondrial respiratory chain complexes (enzymes that are involved in basic energy production), according to a study in the July 2 issue of JAMA.

2 Jul 2014

Genentech agrees to acquire Seragon Pharmaceuticals

Genentech, a member of the Roche Group, today announced it has entered into a definitive agreement to acquire Seragon Pharmaceuticals, Inc., a privately held biotechnology company based in San Diego, California.

2 Jul 2014

Reform roundup: Georgia exchange attracts more insurers; Kansas embraces one part of health law

UnitedHealthcare, Coventry, Cigna and Time Insurance Company have each submitted plans with the state to offer health insurance in the federally run exchange in Georgia next year. They join the five holdovers from this year's exchange that are also submitting rates for review: Alliant Health Plans, Blue Cross and Blue Shield of Georgia, Humana, Kaiser Permanente, and Peach State Health Plans. The state's deadline for applications for the Georgia exchange was midnight Monday (Miller, 6/30).

2 Jul 2014

Global forum calls for accelerated action to improve maternal, newborn and child health

More than 800 leaders and public health experts from around the world opened a landmark two-day meeting in Johannesburg to review new data and call for accelerated action to improve maternal, newborn and child health.

2 Jul 2014

CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

In the first genome-wide analysis of postsurgical pain in children, pediatric researchers identified variations in genes that affect a child's need for pain-control drugs. The findings suggest that at some point physicians may calibrate pain-medication dosages according to a child's individual genetic makeup.

2 Jul 2014

Mayo Clinic researchers uncover 31 genes key to clear cell renal cell carcinoma

A genomic analysis of clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, from 72 patients has uncovered 31 genes that are key to development, growth and spread of the cancer, say researchers from Mayo Clinic in Florida.

2 Jul 2014

Fewer deer, less Lyme disease

Since white-tailed deer serve as the primary host for the adult blacklegged tick (Ixodes scapularis) - the vector for Lyme disease - scientists have wondered whether reducing the number of deer in a given area would also mean fewer cases of Lyme disease. Now, after a 13-year study was conducted, researchers in Connecticut have found that reduced deer populations can indeed lead to a reduction in Lyme disease cases.

2 Jul 2014

State roundup: Christie vows overhaul of pension, health benefits; Ill., Fla. move more into Medicaid managed care

Gov. Chris Christie said he would propose an overhaul to the state's pension and health benefits system later this summer, revisiting an issue that burnished his national political image in 2011 but challenged him this spring when he scaled back promised funding. As the governor signed a $32.5 billion budget on Monday, he vetoed tax increases designed to offset pension costs and called changing the pension and benefits system his main economic priority for 2014 (Dawsey and Haddon, 6/30).

2 Jul 2014

Researchers identify new biomarker that predicts effectiveness of glioblastoma treatment

Researchers at the University of California, San Diego School of Medicine have identified a new biomarker that predicts whether glioblastoma - the most common form of primary brain cancer - will respond to chemotherapy. The findings are published in the July print issue of Oncotarget.

2 Jul 2014

Medical News

MedImmune initiates MEDI8897 phase I clinical studies for treatment of RSV infections

Study explores neurological outcomes in patients treated for traumatic brain injury

Ipsen seeks marketing authorization from FDA for Somatuline Depot 120mg injection

Patient Protection and Affordable Care Act can improve health of the US population

USA witnesses dramatic slowdown in health spending growth over last decade

New gene therapy for Acute Intermittent Porphyria

Research on inflammasomes lays foundations for developing new RA treatments

Australian immunologists uncover additional role for antibody-making 'B cells'

Study results may help prevent eye injuries among soldiers

Eurofins Genomics, AmpTec sign co-marketing agreement for IVT-RNAs

Sugar-coated cells are potentially deadly for cancer patients

Exome sequencing improves diagnosis of mitochondrial disease

Genentech agrees to acquire Seragon Pharmaceuticals

Reform roundup: Georgia exchange attracts more insurers; Kansas embraces one part of health law

Global forum calls for accelerated action to improve maternal, newborn and child health

CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

Mayo Clinic researchers uncover 31 genes key to clear cell renal cell carcinoma

Fewer deer, less Lyme disease

State roundup: Christie vows overhaul of pension, health benefits; Ill., Fla. move more into Medicaid managed care

Researchers identify new biomarker that predicts effectiveness of glioblastoma treatment

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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