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Researchers identify two oncogenes that drive the development of medulloblastoma

A new collaborative study carried out by researchers at Sanford-Burnham Medical Research Institute, UC San Diego, the German Cancer Research Center, the University of Heidelberg (Germany), and 33 other research institutions has identified two oncogenes, called GFI1 and GFI1B, that drive the development of medulloblastoma, the most common malignant brain tumor in children.

23 Jun 2014

Investigators discover novel cellular genes by uncovering uncharacterized RNAs that encode proteins

Case Western Reserve School of Medicine scientists have made an extraordinary double discovery. First, they have identified thousands of novel long non-coding ribonucleic acid (lncRNA) transcripts.

23 Jun 2014

Study explores new ways to improve medications to treat type 2 diabetes

A better understanding of how the transcription factor Peroxisome Proliferator-Activated Receptor Gamma (PPARgamma) works is critical to find new ways to improve medications to treat type 2 diabetes.

23 Jun 2014

Huntington Memorial Hospital patient implanted with tiny, leadless cardiac pacemaker

A Huntington Memorial Hospital patient has become the first patient in the San Gabriel Valley to be implanted with a tiny, leadless cardiac pacemaker. Developed for patients with bradycardia - a heart rate that is too slow - the Nanostim device is designed to be placed directly in a patient's heart without the visible lump, scar and insulated wires (called leads) required for conventional pacemakers.

23 Jun 2014

VA executives received high ratings before scandal

Data released at a congressional hearing shows that all of the 470 senior executives at the VA received annual ratings of "fully successful" over the past four years, even though the health system was having delays in processing compensation claims and veterans were having trouble getting access to care.

23 Jun 2014

States, tech companies wrestle over efforts to fix troubled state marketplace sites

States seek to recoup funds from technology companies that were involved in creating the online insurance portals that malfunctioned.

23 Jun 2014

Italian Medicines Agency grants marketing authorization to ILUVIEN for chronic DME treatment

pSivida Corp., a leader in the development of sustained release, drug delivery products for treating eye diseases, today announced that the Italian Medicines Agency (Agenzia Italiana del Farmaco) has granted marketing authorization to ILUVIEN for the treatment of vision impairment associated with chronic diabetic macular edema (DME) considered insufficiently responsive to available therapies.

23 Jun 2014

People with significant hypothyroidism can experience impaired driving

People with significant hypothyroidism can experience impaired driving similar to those who are driving when intoxicated by alcohol, a new study finds.

23 Jun 2014

Researchers find possible biological reason why people with diabetes are prone to depression

Researchers have found a possible biological reason why people with diabetes are prone to depression.

23 Jun 2014

Private insurers clamp down on drug prices

More health plans are refusing to cover certain brand-name drugs unless drugmakers offer discounts for them, reports The New York Times.

23 Jun 2014

Women who develop gestational diabetes perform worse on cognitive function tests

Women who develop diabetes during pregnancy, called gestational diabetes, perform worse on cognitive function tests than do women with a normal pregnancy, according to a new study from Turkey.

23 Jun 2014

XenoPort initiates XP23829 Phase 2 clinical trial in patients with psoriasis

XenoPort, Inc. announced today that it has initiated a Phase 2 clinical trial of XP23829, its proprietary investigational next-generation fumaric acid product candidate. The trial is a multi-center, randomized, double-blind, placebo-controlled study designed to assess the efficacy and safety of XP23829 as a potential treatment of patients with moderate-to-severe chronic plaque-type psoriasis.

23 Jun 2014

Empagliflozin lowers blood pressure in patients with Type 2 diabetes and hypertension

An investigational drug to treat Type 2 diabetes, empagliflozin, lowers blood pressure in patients with Type 2 diabetes and hypertension (high blood pressure), a new study finds.

23 Jun 2014

Treatment with diabetes drug liraglutide improves cardiovascular risk factors

Treatment with the diabetes drug liraglutide, in combination with diet and exercise, led to a significant reduction in weight and improved a number of cardiovascular risk factors, including high blood pressure and high cholesterol, according to a multicenter study.

23 Jun 2014

Patient injuries mean Medicare payment penalties for some hospitals

The preliminary analysis of penalties would lower Medicare payments to these hospitals by 1 percent for a year. Elsewhere, lawmakers introduce legislation to change how hospitals that serve a large number of poor patients are affected by Medicare's penalties.

23 Jun 2014

Medical News

Researchers identify two oncogenes that drive the development of medulloblastoma

Investigators discover novel cellular genes by uncovering uncharacterized RNAs that encode proteins

Study explores new ways to improve medications to treat type 2 diabetes

Huntington Memorial Hospital patient implanted with tiny, leadless cardiac pacemaker

VA executives received high ratings before scandal

States, tech companies wrestle over efforts to fix troubled state marketplace sites

Italian Medicines Agency grants marketing authorization to ILUVIEN for chronic DME treatment

People with significant hypothyroidism can experience impaired driving

Researchers find possible biological reason why people with diabetes are prone to depression

Private insurers clamp down on drug prices

Women who develop gestational diabetes perform worse on cognitive function tests

XenoPort initiates XP23829 Phase 2 clinical trial in patients with psoriasis

Empagliflozin lowers blood pressure in patients with Type 2 diabetes and hypertension

Treatment with diabetes drug liraglutide improves cardiovascular risk factors

Patient injuries mean Medicare payment penalties for some hospitals

Denosumab increases bone density for postmenopausal women with osteoporosis

Long-term mild cold exposure can stimulate brown fat growth

More twists in Capitol Hill insider-trading probe

BPA appears to increase proliferation of breast cancer cells, diminish effectiveness of treatments

Researchers shown how free radicals contribute to fatty liver disease

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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