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Phase 3 ASPIRE clinical trial meets primary endpoint of progression-free survival

Amgen and its subsidiary, Onyx Pharmaceuticals, Inc., today announced that a planned interim analysis demonstrated that the Phase 3 clinical trial ASPIRE (CArfilzomib, Lenalidomide, and DexamethaSone versus Lenalidomide and Dexamethasone for the treatment of PatIents with Relapsed Multiple MyEloma) met its primary endpoint of progression-free survival (PFS).

4 Aug 2014

Neuralstem doses final patient with NSI-566 stem cells in Phase II trial

Neuralstem, Inc. announced that the final patient was treated in its Phase II trial using NSI-566 spinal cord-derived neural stem cells in the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease).

4 Aug 2014

Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results

FEI is pleased to announce that researchers at the NIH-FEI Living Lab for Structural Biology have achieved breakthrough biological results, using FEI’s Titan Krios™ transmission electron microscope (TEM), to elucidate the structural mechanism by which glutamate receptors participate in the transmission of signals between neurons in the brain. Their work is described in Nature, “Structural Mechanism of Glutamate Receptor Activation and Desensitization,” by Meyerson, et al., (DOI: 10.1038/nature13603), http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13603.html .

From Thermo Fisher Scientific – Electron Microscopy Solutions 4 Aug 2014

FDA clears ElMindA's BNA Analysis System for assessment of brain function

ElMindA Ltd. announced today that the United States Food and Drug Administration has cleared the company's BNA Analysis System for the assessment of brain function. Brain Network Activity (BNA) combines non-invasive, multi-channel EEG technology with sophisticated signal processing and analysis algorithms to measure patterns of brain networks activated during specific brain processes and deliver both quantitative and qualitative insights into brain functionality.

4 Aug 2014

Henry Schein net sales increase 9.3% to $2.6 billion in Q2 2014

Henry Schein, Inc., the world's largest provider of health care products and services to office-based dental, animal health and medical practitioners, today reported record financial results for the quarter ended June 28, 2014.

4 Aug 2014

Shimadzu Medical Systems wins 2014 Best in KLAS award for Digital X-Ray

Shimadzu Medical Systems USA, a subsidiary of Shimadzu Corporation, receives a 2014 Best in KLAS award for Digital X-Ray.

4 Aug 2014

Tecomet signs agreement to acquire Symmetry Medical's OEM Solutions business for $450 million

Tecomet Inc., a Genstar Capital portfolio company and precision contract manufacturer supporting the medical device and aerospace industries, today announced that it has signed a definitive agreement with Symmetry Medical Inc. to acquire its OEM Solutions business segment for $450 million.

4 Aug 2014

Community-based doulas dramatically increase breastfeeding rates in underserved communities

A new study by the federal government finds that community-based doulas – based on a program started by HealthConnect One – dramatically increase breastfeeding rates in underserved communities, where a baby's exposure to breast milk can help mitigate the impacts of poverty.

4 Aug 2014

Scientists shed new light on why teenagers are susceptible to meningitis and septicaemia

University of York scientists have shed new light on why teenagers and young adults are particularly susceptible to meningitis and septicaemia.

4 Aug 2014

Metformin and SGLT2 inhibitors together reduce blood sugar levels

Metformin and SGLT2 inhibitors together reduce the blood sugar levels considerably more effectively than either drug alone.

4 Aug 2014

Leg ulcer treatment to be studied by sport scientists at Sheffield Hallam University

Sport and exercise scientists at Sheffield Hallam University have started a new study into the treatment of Chronic Venous Insufficiency (CVI), which affects patients' legs, often causing painful leg ulcers.

From Sheffield Hallam University 4 Aug 2014

First Edition: August 4, 2014

Today's headlines include a variety of health policy stories reflecting developments on the state level.

4 Aug 2014

Lung cancer diagnosis tool can be used safely in elderly to make more accurate diagnosis

Lung cancer diagnosis tool shown to be safe and effective for older patientsA recent study in Manchester has found that a procedure to take tissue samples from lung cancer patients can be used safely in the elderly - allowing doctors to make a more accurate diagnosis and to choose appropriate treatment.

From The University of Manchester 4 Aug 2014

Epigenetic control of serotonin transporter predicts human brain function

The tiny addition of a chemical mark atop a gene that is well known for its involvement in clinical depression and posttraumatic stress disorder can affect the way a person's brain responds to threats, according to a new study by Duke University researchers.

4 Aug 2014

New information on limitations and potential for development of transcranial ultrasound therapy

A recent study completed at the University of Eastern Finland provides new information on the limitations and potential new directions for the future development of transcranial ultrasound therapy.

4 Aug 2014

Findings shed light on why PPARγ activators have side effect of promoting weight gain

The brain plays a central role in regulating appetite and whole-body metabolism. A protein known as PPARγ is important in the brain's control of food intake and body weight, but the identity of the neurons regulating this process has been unclear.

4 Aug 2014

ACAAI offers practical solutions to improve asthma problem in older women

Women over the age of 65 face numerous barriers to good health: an increased risk for obesity, greater struggles against poverty and higher rates of asthma with worse health outcomes.

4 Aug 2014

Nutrition support protocol effective in increasing nutrients provided to critically ill patients

Varying practices and frequent lapses in nutrition delivery can put critically ill patients at greater risk for malnutrition and associated complications, according to an article in the August issue of Critical Care Nurse (CCN).

4 Aug 2014

Clinical trial to look for genetic information in cancer patients

Sanford Health is working to enroll approximately 50 adult patients whose cancer has progressed after the first line of treatment or who have rare cancers without standard treatment options in a clinical trial to look for genetic information that could help customize treatment options.

4 Aug 2014

New genetic markers signal increased risk of developing pancreatic cancer

A large DNA analysis of people with and without pancreatic cancer has identified several new genetic markers that signal increased risk of developing the highly lethal disease, report scientists from Dana-Farber Cancer Institute.

4 Aug 2014

Medical News

Phase 3 ASPIRE clinical trial meets primary endpoint of progression-free survival

Neuralstem doses final patient with NSI-566 stem cells in Phase II trial

Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results

FDA clears ElMindA's BNA Analysis System for assessment of brain function

Henry Schein net sales increase 9.3% to $2.6 billion in Q2 2014

Shimadzu Medical Systems wins 2014 Best in KLAS award for Digital X-Ray

Tecomet signs agreement to acquire Symmetry Medical's OEM Solutions business for $450 million

Community-based doulas dramatically increase breastfeeding rates in underserved communities

Scientists shed new light on why teenagers are susceptible to meningitis and septicaemia

Metformin and SGLT2 inhibitors together reduce blood sugar levels

Leg ulcer treatment to be studied by sport scientists at Sheffield Hallam University

First Edition: August 4, 2014

Lung cancer diagnosis tool can be used safely in elderly to make more accurate diagnosis

Epigenetic control of serotonin transporter predicts human brain function

New information on limitations and potential for development of transcranial ultrasound therapy

Findings shed light on why PPARγ activators have side effect of promoting weight gain

ACAAI offers practical solutions to improve asthma problem in older women

Nutrition support protocol effective in increasing nutrients provided to critically ill patients

Clinical trial to look for genetic information in cancer patients

New genetic markers signal increased risk of developing pancreatic cancer

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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