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Johns Hopkins biochemists figure out HIV-fighting activity of enzyme

Johns Hopkins biochemists have figured out what is needed to activate and sustain the virus-fighting activity of an enzyme found in CD4+ T cells, the human immune cells infected by HIV. The discovery could launch a more effective strategy for preventing the spread of HIV in the body with drugs targeting this enzyme, they say.

2 May 2014

UCSD neurosurgeons study MRI-guided biopsy approach to diagnose patients with brain cancer

Neurosurgeons at UC San Diego Heath System have, for the first time, combined real-time magnetic resonance imaging (MRI) technology with novel non-invasive cellular mapping techniques to develop a new biopsy approach that increases the accuracy of diagnosis for patients with brain cancer.

2 May 2014

Ruthigen files IND Application to FDA for lead drug candidate RUT58-60

Ruthigen, Inc., a biopharmaceutical company focused on the discovery, development and commercialization of novel therapeutics designed to prevent and treat infection in invasive applications, today announced that the Company has submitted an Investigational New Drug (IND) Application to the U.S. Food and Drug Administration for its lead drug candidate RUT58-60.

2 May 2014

New hope for improved diagnosis of children with TB

A distinctive genetic 'signature' found in the blood of children with tuberculosis (TB) offers new hope for improved diagnosis of the disease.

2 May 2014

CVS Caremark net revenues increase 6.3% to $32.7 billion in Q1 2014

CVS Caremark Corporation today announced operating results for the three months ended March 31, 2014.

2 May 2014

Isis Pharmaceuticals reports final data from ISIS-APOCIIIRx Phase 2 study in patients with FCS

Isis Pharmaceuticals, Inc. announced the final data from its Phase 2 study of ISIS-APOCIIIRx as a monotherapy in patients with familial chylomicronemia syndrome, or FCS.

2 May 2014

First Edition: May 2, 2014

Today's headlines include coverage of the latest round of health insurance enrollment data released by the Obama administration.

2 May 2014

Teen suicide clusters linked to newspaper reports

Heightened newspaper coverage after a suicide might have a significant impact on the initiation of some teenage suicide clusters, according to new research published in The Lancet Psychiatry journal.

2 May 2014

Longer looks: Failure to meet Veterans' health needs; new views of the 1918 flu pandemic; a crumbling mental health system

At least 40 U.S. veterans died waiting for appointments at the Phoenix Veterans Affairs Health Care system, many of whom were placed on a secret waiting list.

2 May 2014

Study provides insight into effects of interleukin-27 in regulatory T-cell biology, physiological functions of IL-27

In a new report published in the Journal of Leukocyte Biology, scientists lay the groundwork for the development of novel tumor therapies that may help rid the body of cancer by inhibiting the recruitment of a specific suppressive immune cell type called "regulatory T-cells." The approach described in the report shows that an immune molecule, called interleukin-27, promotes the recruitment of regulatory T-cells.

2 May 2014

New research suggests that Kindlin-3 regulates 2 major hallmarks of breast cancer

A protein believed to be limited to the hematopoietic system, called Kindlin-3, has been identified as a major player in both the formation and spread of breast cancer to other organs.

2 May 2014

DFID awards more than £9.3M to CMNH to continue work with midwives in Kenya

With International Day of the Midwife just around the corner (5th May), LSTM's Centre for Maternal and Newborn Health (CMNH) has been successful in securing a new -9.3 million grant to continue their work with midwives in Kenya.

2 May 2014

14th Plymouth Symposium focuses on issues relating to obesity, diabetes and metabolic syndrome

The 14th Plymouth Symposium on obesity, diabetes and metabolic syndrome, 'Diabesity', will take place at the Plymouth Postgraduate Medical Centre at Derriford Hospital, Plymouth, UK, on 22nd May 2014.

2 May 2014

State highlights: Calif. panel backs coverage for those in state illegally; Mich. mental health funding cuts; Ga. rural hospitals

Senate Panel Backs Health Coverage For Those In The Country Illegally A proposal to have the state fund an expansion of health care to cover low-income residents in the country illegally was advanced Wednesday by the state Senate Health Committee. Sen. Ricardo Lara (D-Bell Gardens) introduced SB 1005, which would use state money to expand Medi-Cal eligibility to those with an annual income of about $15,000 or less for one person but who have not been able to qualify because of their immigration status. People in the country illegally are prohibited from participating in the federal Affordable Care Act program providing subsidized care (McGreevy, 4/30).

2 May 2014

Acorda gets FDA Complete Response Letter for PLUMIAZ Nasal Spray NDA

Acorda Therapeutics, Inc. today announced that the U.S. Food and Drug Administration has issued a Complete Response Letter (CRL) for the New Drug Application (NDA) for PLUMIAZ (diazepam) Nasal Spray for the treatment of people with epilepsy who experience cluster seizures.

2 May 2014

Findings highlight challenges faced by people shopping for health insurance

When selecting a health insurance plan, both uninsured, tech-savvy young adults and uninsured low-income, rural adults had trouble understanding their insurance options. Many selected insurance plans that were more expensive than required for their health care needs, finds a new study in Health Services Research.

2 May 2014

New mobile apps to help manage chronic pain patients

Mobile medicine is helping chronic pain patients cope with and manage their condition thanks to new smartphone apps, which can track patients from a distance and monitor pain, mood, physical activity, drug side effects, and treatment compliance.

2 May 2014

Study suggests reasons for disparities in obesity rates between African-American and white women

A new study suggests the reasons for disparities in obesity rates between African-American and white women are far more complex than the usual go-to culprits of socioeconomics, fruit and vegetable intake, and exercise.

2 May 2014

Tens of thousands of premature deaths could be prevented each year

Heart disease, cancer, chronic lower respiratory diseases, stroke, and unintentional injuries cause nearly 900,000 premature deaths in the US each year. A recent study showed that 20–40% of deaths from each of these causes could be prevented.

2 May 2014

State exchanges spent far more to reach consumers

States that ran their own insurance marketplaces under the health law or those that partnered with the federal government spent significantly more on outreach and enrollment efforts than states that used the federal marketplace, according to a study funded by the Robert Wood Johnson Foundation.

2 May 2014

Medical News

Johns Hopkins biochemists figure out HIV-fighting activity of enzyme

UCSD neurosurgeons study MRI-guided biopsy approach to diagnose patients with brain cancer

Ruthigen files IND Application to FDA for lead drug candidate RUT58-60

New hope for improved diagnosis of children with TB

CVS Caremark net revenues increase 6.3% to $32.7 billion in Q1 2014

Isis Pharmaceuticals reports final data from ISIS-APOCIIIRx Phase 2 study in patients with FCS

First Edition: May 2, 2014

Teen suicide clusters linked to newspaper reports

Longer looks: Failure to meet Veterans' health needs; new views of the 1918 flu pandemic; a crumbling mental health system

Study provides insight into effects of interleukin-27 in regulatory T-cell biology, physiological functions of IL-27

New research suggests that Kindlin-3 regulates 2 major hallmarks of breast cancer

DFID awards more than £9.3M to CMNH to continue work with midwives in Kenya

14th Plymouth Symposium focuses on issues relating to obesity, diabetes and metabolic syndrome

State highlights: Calif. panel backs coverage for those in state illegally; Mich. mental health funding cuts; Ga. rural hospitals

Acorda gets FDA Complete Response Letter for PLUMIAZ Nasal Spray NDA

Findings highlight challenges faced by people shopping for health insurance

New mobile apps to help manage chronic pain patients

Study suggests reasons for disparities in obesity rates between African-American and white women

Tens of thousands of premature deaths could be prevented each year

State exchanges spent far more to reach consumers

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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