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Researchers identify new Chinese herbal medicine that inhibits hepatitis C virus activity

Data from a late-breaking abstract presented at the International Liver CongressTM 2014 identifies a new compound, SBEL1, that has the ability to inhibit hepatitis C virus (HCV) activity in cells at several points in the virus' lifecycle.

15 Apr 2014

CBO projects health law subsidies will cost less than previously expected

The new CBO projections find that the health law's expansion of health coverage will, from 2015–2024, cost $104 billion less than previously projected.

15 Apr 2014

Obeticholic acid meets primary composite endpoint in Phase III study

Results from an international Phase III study presented today at the International Liver CongressTM 2014 have shown obeticholic acid (OCA) given to patients suffering from Primary Biliary Cirrhosis (PBC) who previously had an inadequate response to, or have been unable to tolerate ursodeoxycholic acid (UDCA), produced meaningful biochemical and clinical improvements. UDCA is the only therapy currently approved to treat PBC.

15 Apr 2014

TSRI announces formation of Scripps Advance

The Scripps Research Institute (TSRI) today announced the formation of Scripps Advance, a new drug discovery initiative to translate early-stage biomedical research projects, both internal and external to TSRI, into clinical development candidates.

15 Apr 2014

New technique of single-cell genomic analysis to reverse tissue engineering

Consider the marvel of the embryo. It begins as a glob of identical cells that change shape and function as they multiply to become the cells of our lungs, muscles, nerves and all the other specialized tissues of the body.

15 Apr 2014

Teenagers who have little hope for future may commit more serious offenses

In a UT Dallas study involving serious youth offenders, the answer to one open-ended question predicted the teenagers' offending patterns for the next seven years: "How long do you think you'll live?"

15 Apr 2014

Vivolux receives FDA clearance to proceed with phase I/II clinical trial of VLX600

Vivolux AB, a drug discovery company specialized in cancer treatment, announced today that the FDA has granted clearance to proceed with VLX600 into the clinical phase I/II. VLX600 is one of the company's promising projects, and which was recently published in the journal Nature Communications.

15 Apr 2014

Drugs used to treat osteoporosis appear to prevent cell membrane repair

A class of drugs widely used to treat osteoporosis appears to impede a cell's ability to repair a protective outer membrane that helps determine what enters and exits, researchers report.

15 Apr 2014

Researchers develop translucent panel that redirects sunlight onto alleyways

In dense, urban centers around the world, many people live and work in dim and narrow streets surrounded by tall buildings that block sunlight. And as the global population continues to rise and buildings are jammed closer together, the darkness will only spread.

15 Apr 2014

Va. GOP not backing down in Medicaid stalemate

Despite appeals from traditional allies such as local hospitals, chambers of commerce and business leaders, Republicans in Virginia's House of Delegates remain firm in their stand against expansion. Meanwhile, Pennsylvania's request to set up a modified expansion is moving into a negotiation phase with federal officials, and union members take the fight to voters in Florida.

15 Apr 2014

Research: Antibiotics for Q fever can contribute to obesity

Scientists have unearthed still more evidence that antibiotics can contribute to obesity. Research published ahead of print in the journal Antimicrobial Agents and Chemotherapy suggests that patients on long-term antibiotic treatment gained weight and had significant changes in their gut microbiota.

15 Apr 2014

Researchers figure out role of birth weight and breastfeeding in long run health outcomes

Lower weight babies and babies who aren't breastfed or not breastfed for long are at greater risk of developing chronic inflammation and related health problems later in life, according to a new study.

15 Apr 2014

What is 'preventive' care? answer causing patient-doctor friction

Access to preventive care at no charge to the patient is a tenet of the health law, but differences over just what's considered "preventive" are causing friction between doctors and patients, reports The Wall Street Journal. Other stories look at how California community clinics have yet to see increased demand for primary care doctors and how plans are targeting newly insured diabetics to avoid costly complications.

15 Apr 2014

Highligts: Calif.'s medical system for prisons; gender therapy in Boston; Ga. public health money

California's $840-million medical prison -- the largest in the nation -- was built to provide care to more than 1,800 inmates. When fully operational, it was supposed to help the state's prison system emerge from a decade of federal oversight brought on by the persistent neglect and poor medical treatment of inmates.

15 Apr 2014

Study: Immunization program in UK has reduced HPV infections in young women

Each year around 2,000-2,500 women are diagnosed with cervical cancer in England, the most common cancer in women under 35. Infection with high-risk human papillomavirus (HR HPV) types 16 and 18 is responsible for around 70-80% of cervical cancers.

15 Apr 2014

New drug combination proves effective in treating patients with HCV genotype 1

Treatment options for the 170 million people worldwide with chronic Hepatitis C Virus (HCV) are evolving rapidly, although the available regimens often come with significant side effects. Two multi-center clinical trials led by Beth Israel Deaconess Medical Center show promise for a new option that could help lead to both an increase in patients cured with a much more simple and tolerable all oral therapy.

15 Apr 2014

Researchers find link between patient satisfaction and SDM during radiation treatment

Playing an active role in their radiation treatment decisions leaves cancer patients feeling more satisfied with their care, and may even relieve psychological distress around the experience, researchers from the Perelman School of Medicine at the University of Pennsylvania report in the journal Cancer.

15 Apr 2014

Residential aged care facilities need to tackle antipsychotic usage in dementia patients

NPS MedicineWise has welcomed the recommendations of the recently released Senate Committee report on the care of Australians living with dementia and is encouraging residential aged care facilities to tackle the overuse of antipsychotics medicines in people with behavioural or psychological problems associated with dementia.

15 Apr 2014

Study: Chemotherapy before surgery improves survival in patients with muscle-invasive bladder cancer

Contrary to treatment guidelines for high-risk bladder cancer, chemotherapy before or after surgery is not commonly used in routine clinical practice. The findings are published early online in Cancer, a peer-reviewed journal of the American Cancer Society.

15 Apr 2014

Study shows 25 percent of Colorado foster kids on psychotropic drugs

The rate is 12 times greater than for other children on government insurance, a new study in Colorado finds.

15 Apr 2014

Medical News

Researchers identify new Chinese herbal medicine that inhibits hepatitis C virus activity

CBO projects health law subsidies will cost less than previously expected

Obeticholic acid meets primary composite endpoint in Phase III study

TSRI announces formation of Scripps Advance

New technique of single-cell genomic analysis to reverse tissue engineering

Teenagers who have little hope for future may commit more serious offenses

Vivolux receives FDA clearance to proceed with phase I/II clinical trial of VLX600

Drugs used to treat osteoporosis appear to prevent cell membrane repair

Researchers develop translucent panel that redirects sunlight onto alleyways

Va. GOP not backing down in Medicaid stalemate

Research: Antibiotics for Q fever can contribute to obesity

Researchers figure out role of birth weight and breastfeeding in long run health outcomes

What is 'preventive' care? answer causing patient-doctor friction

Highligts: Calif.'s medical system for prisons; gender therapy in Boston; Ga. public health money

Study: Immunization program in UK has reduced HPV infections in young women

New drug combination proves effective in treating patients with HCV genotype 1

Researchers find link between patient satisfaction and SDM during radiation treatment

Residential aged care facilities need to tackle antipsychotic usage in dementia patients

Study: Chemotherapy before surgery improves survival in patients with muscle-invasive bladder cancer

Study shows 25 percent of Colorado foster kids on psychotropic drugs

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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