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Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

Novartis today announced that The New England Journal of Medicine (NEJM) published clinical trial results showing the investigational compound LDK378 (ceritinib) achieved an overall response rate (ORR, including complete response [CR] and partial response [PR]) of 58% and a median progression-free survival (PFS) of seven months in adults with advanced anaplastic lymphoma kinase positive (ALK+) non-small cell lung cancer (NSCLC) who received 400 mg or higher of LDK378 per day.

28 Mar 2014

Everyday Health prices initial public offering of common stock

Everyday Health, Inc. today announced the pricing of its initial public offering of 7,150,000 shares of its common stock at a price to the public of $14.00 per share.

28 Mar 2014

6 million enrollees in sight, some analysts say

Three million of those enrollees alone are in California while Georgia enrollment moves up slightly to more than 177,000.

28 Mar 2014

Formula for peak exercise heart rate does not account for differences between men and women

The formula for peak exercise heart rate that doctors have used for decades in tests to diagnose heart conditions may be flawed because it does not account for differences between men and women, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

Hospital infection rates down, but patients still dying of preventable causes

Hospitals and nursing homes have been trying to cut the facility-acquired infection rates, which has worked better for some conditions than others.

28 Mar 2014

Discovery could lead to new medications for cancer, say Rice University scientists

A new understanding of proteins at the nexus of a cell's decision to survive or die has implications for researchers who study cancer and age-related diseases, according to biophysicists at the Rice University-based Center for Theoretical Biological Physics.

28 Mar 2014

CDC identifies six new cases of people with Heartland virus

The Centers for Disease Control and Prevention in collaboration with health officials in Missouri and Tennessee have identified six new cases of people sick with Heartland virus: five in Missouri and one in Tennessee. The new cases, discovered in 2012 and 2013, are described today in CDC's Morbidity and Mortality Weekly Report.

28 Mar 2014

Endo Health Solutions to commence exchange offers on all outstanding unsecured Senior Notes

Endo International plc announced today that its wholly-owned subsidiary, Endo Health Solutions Inc. ("EHSI"), will commence offers to exchange any and all of the outstanding unsecured 7% Senior Notes due 2019, 7.00% Senior Notes due 2020 and 7¼% Senior Notes due 2022 issued by EHSI, which have an aggregate principal amount outstanding of $1.3 billion (collectively, the "Existing EHSI Notes"), for new unsecured 7.00% Senior Notes due 2019, 7.00% Senior Notes due 2020 and 7.25% Senior Notes due 2022 (collectively, the "New Endo Finance Notes"), respectively, issued by Endo Finance LLC ("Endo Finance") and Endo Finco Inc.

28 Mar 2014

Senate Democrats ready health law changes

The lawmakers will likely meet this week to set principles for the changes, which could include new allowing lower coverage: "copper" insurance plans.

28 Mar 2014

Heart failure patients benefit from new device till transplant

The largest single-center study of patients implanted with a total artificial heart finds the device may help patients in severe heart failure survive until they can receive a heart transplant, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

Viewpoints: Generic drug warnings; Medicare Advantage 'scam'

Late last year, the Food and Drug Administration proposed sensible regulations that would authorize the makers of generic drugs to update safety labels independently, without waiting for F.D.A. approval, to warn of newly discovered risks.

28 Mar 2014

Jackson Lab professor wins nearly $2M grant for investigating role of noncoding RNAs in cancer

The National Cancer Institute has awarded a three-year grant totaling $2,168,535 to Professor Yijun Ruan, Ph.D., of The Jackson Laboratory for Genomic Medicine, for his research into the role of noncoding RNAs in cancer and other diseases.

28 Mar 2014

Scientists identify two markers that predict patient's resistance to radiation therapy for cancer

An international team of researchers, led by Beaumont Health System's Jan Akervall, M.D., Ph.D., looked at biomarkers to determine the effectiveness of radiation treatments for patients with squamous cell cancer of the head and neck.

28 Mar 2014

Antidepressant medications during pregnancy linked with increased rates of preterm birth

Antidepressant medications taken by pregnant women are associated with increased rates of preterm birth. This finding reinforces the notion that antidepressants should not be used by pregnant women in the absence of a clear need that cannot be met through alternative approaches, say researchers from Brigham and Women's Hospital, Vanderbilt University, MetroWest Medical Center, and Tufts Medical Center.

28 Mar 2014

Tgen professor to receive 2014 Hope Funds Award for developing numerous cancer treatments

Dr. Daniel D. Von Hoff, who has been instrumental in developing numerous new cancer treatments, is among this year's recipients of the Award of Excellence from the Hope Funds for Cancer Research.

28 Mar 2014

Study links broken heart syndrome to natural disasters

Dramatic spikes in cases of Takotsubo cardiomyopathy, also called broken heart syndrome, were found in two states after major natural disasters, suggesting the stress of disasters as a likely trigger, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

Medical News

Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

Everyday Health prices initial public offering of common stock

6 million enrollees in sight, some analysts say

Formula for peak exercise heart rate does not account for differences between men and women

Hospital infection rates down, but patients still dying of preventable causes

Discovery could lead to new medications for cancer, say Rice University scientists

CDC identifies six new cases of people with Heartland virus

Endo Health Solutions to commence exchange offers on all outstanding unsecured Senior Notes

Senate Democrats ready health law changes

Heart failure patients benefit from new device till transplant

Viewpoints: Generic drug warnings; Medicare Advantage 'scam'

Jackson Lab professor wins nearly $2M grant for investigating role of noncoding RNAs in cancer

Scientists identify two markers that predict patient's resistance to radiation therapy for cancer

Antidepressant medications during pregnancy linked with increased rates of preterm birth

Tgen professor to receive 2014 Hope Funds Award for developing numerous cancer treatments

Study links broken heart syndrome to natural disasters

People unwilling to swallow soda tax, size restrictions

Lack of insight linked to disengagement with CBT for psychosis

Staging model, biomarker proposed for bipolar disorder

EEG findings specific to mood state in bipolar disorder

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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