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Researchers use retro approach to produce new drugs

This alternative approach to creating artificial organic molecules, called bioretrosynthesis, was first proposed four years ago by Brian Bachmann, associate professor of chemistry at Vanderbilt University. Now Bachmann and a team of collaborators report that they have succeeded in using the method to produce the HIV drug didanosine.

25 Mar 2014

Va. lawmakers back to Richmond, Medicaid expansion hangs in the balance

Vice President Joseph Biden believes that GOP officials in every state will have to accept the expansion. And Florida's Sen. Bill Nelson, a Democrat, said he's talked with federal officials about a plan to go around the GOP-controlled state legislature.

25 Mar 2014

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

Researchers from Boston University School of Medicine have found that the diabetic drug, pramlintide, reduces amyloid-beta peptides, a major component of Alzheimer's disease (AD) in the brain and improves learning and memory in two experimental AD models.

25 Mar 2014

Faster DNA sequencing techniques more likely to improve care for patients with breast cancer

Faster and cheaper DNA sequencing techniques will likely improve care for patients with breast cancer but also create challenges for clinicians as they counsel patients on their treatment options.

25 Mar 2014

CytRx initiates Phase 3 clinical trial to evaluate efficacy of aldoxorubicin in STS patients

CytRx Corporation (Nasdaq: CYTR), a biopharmaceutical research and development company specializing in oncology, today announced it has initiated a pivotal global Phase 3 clinical trial to evaluate the efficacy and safety of aldoxorubicin as a second-line treatment for patients with soft tissue sarcoma (STS) under a Special Protocol Assessment with the FDA.

25 Mar 2014

More skin cancer awareness needed for minorities, says Henry Ford Hospital dermatologist

More awareness about skin cancer is needed for minorities because they believe they are at low risk of developing it, says Henry Ford Hospital dermatologist Diane Jackson-Richards, M.D.

25 Mar 2014

Nasal spray holds promise as potential alternative therapeutic approach for depression

A nasal spray that delivers a peptide to treat depression holds promise as a potential alternative therapeutic approach, research from the Centre for Addiction and Mental Health (CAMH) shows.

25 Mar 2014

Treatment with natalizumab in patients with MS appears linked with JC virus infection

Treatment with natalizumab in patients with multiple sclerosis (MS) appears linked with JC virus (JCV) infection, which can lead to a rare and often fatal demyelinating disease of the central nervous system called progressive multifocal leukoencephalopathy (PML) that destroys the myelin that protects nerve cells.

25 Mar 2014

IDRI awarded grant extension of $3.4M for identifying new leads and drug targets for tuberculosis

IDRI's drug discovery efforts continue to grow with a recently awarded grant extension of $3.4 million from the Bill & Melinda Gates Foundation. The additional funding was awarded to Tanya Parish, Ph.D., IDRI's Vice President of Drug Discovery, and supplements an earlier grant awarded in 2010, for a total of $7.8 million.

25 Mar 2014

Homeless people who have suffered TBI are more likely to visit Emergency Department

Homeless and vulnerably housed people who have suffered a traumatic brain injury at some point in their life are more likely to visit an Emergency Department, be arrested or incarcerated, or be victims of physical assault, new research has found.

24 Mar 2014

High-protein meal and exercise recipe for calorie-burning in some women

New research shows that for some women, a high-protein meal followed by 30 minutes of moderate exercise is an effective way of burning calories, especially when compared to exercising on an empty stomach.

24 Mar 2014

Prostate stiffness is a risk factor for voiding dysfunction

Prostate elasticity is an independent risk factor for urinary voiding symptoms, although not for lower urinary tract symptoms in general or storage symptoms, clinical research indicates.

24 Mar 2014

Antibiotics for UTI often taken before, after incontinence surgery

One in four women undergoing surgery for urinary incontinence has recently taken antibiotics for a urinary tract infection, a large population-based study shows.

24 Mar 2014

Nightmares heighten insomnia impact on depression

Nightmares and insomnia contribute independently and additively to depression severity, cross-sectional study findings show.

24 Mar 2014

CSP analogues may attenuate S. pneumoniae virulence, resistance

The spread of virulent, antibiotic-resistant strains of Streptococcus pneumoniae may be controllable through the use of competence-stimulating peptide analogues, US researchers believe.

24 Mar 2014

Cell-free DNA analysis allows noninvasive tumour genotype monitoring

Noninvasive tumour genotyping using cell-free plasma DNA analysis is feasible, say US researchers who believe the technique will aid patient diagnosis and monitoring.

24 Mar 2014

‘Residual risk’ concern for treated Japanese hypertension patients

Physicians should be alert to other sources of cardiovascular risk in patients with hypertension, even if they are receiving optimal antihypertensive treatment, say Japanese researchers.

24 Mar 2014

Doctor Trusted grants certification to IMS Supplements' Best Prostate Formula

Online health retailer IMS Supplements, Inc. has recently been approved to display a doctor's seal of approval, a major benefit granted by consumer protection service Doctor Trusted.

24 Mar 2014

Certain drugs in Obamacare plans carry hefty pricetags

Insurers selling Obamacare plans have set drug prices according to a tiered system that in some cases requires consumers to pay as much as 50 percent of the cost, The Associated Press writes.

24 Mar 2014

AMRI signs definitive agreement to acquire all outstanding shares of Cedarburg Pharmaceuticals

AMRI today announced that it has signed a definitive agreement to acquire all the outstanding shares of Cedarburg Pharmaceuticals, Inc. for $38.2 million in cash.

24 Mar 2014

Medical News

Researchers use retro approach to produce new drugs

Va. lawmakers back to Richmond, Medicaid expansion hangs in the balance

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

Faster DNA sequencing techniques more likely to improve care for patients with breast cancer

CytRx initiates Phase 3 clinical trial to evaluate efficacy of aldoxorubicin in STS patients

More skin cancer awareness needed for minorities, says Henry Ford Hospital dermatologist

Nasal spray holds promise as potential alternative therapeutic approach for depression

Treatment with natalizumab in patients with MS appears linked with JC virus infection

IDRI awarded grant extension of $3.4M for identifying new leads and drug targets for tuberculosis

Homeless people who have suffered TBI are more likely to visit Emergency Department

High-protein meal and exercise recipe for calorie-burning in some women

Prostate stiffness is a risk factor for voiding dysfunction

Antibiotics for UTI often taken before, after incontinence surgery

Nightmares heighten insomnia impact on depression

CSP analogues may attenuate S. pneumoniae virulence, resistance

Cell-free DNA analysis allows noninvasive tumour genotype monitoring

‘Residual risk’ concern for treated Japanese hypertension patients

Doctor Trusted grants certification to IMS Supplements' Best Prostate Formula

Certain drugs in Obamacare plans carry hefty pricetags

AMRI signs definitive agreement to acquire all outstanding shares of Cedarburg Pharmaceuticals

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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