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Scientists discover novel antibody-based therapy that targets progression of kidney fibrosis

Scientists from the University of Sheffield have developed a novel antibody-based therapy which targets the progression of life threating kidney fibrosis.

16 Feb 2014

Findings underscore need to increase access to new treatments for minority groups, older patients

While new and better treatments have improved the odds of survival for patients diagnosed late stage colorectal cancer, that progress has been largely confined to non-Hispanic whites and Asians and those under age 65, according to a new study. American Cancer Society researchers led by Helmneh Sineshaw, M.D., MPH, find there have been no significant increases in survival rates for Hispanics and non-Hispanic blacks with metastatic colon cancer.

16 Feb 2014

University of Adelaide research reveals new approach for bowel cancer treatment

University of Adelaide research has shown for the first time that grape seed can aid the effectiveness of chemotherapy in killing colon cancer cells as well as reducing the chemotherapy's side effects.

16 Feb 2014

Research findings have important implications for personalized treatment of alcohol abuse

Heavy drinking is common in the United States and takes a personal and societal toll, with an annual estimated cost of $223.5 billion due to losses in workplace productivity, health care and criminal justice expenses.

16 Feb 2014

Finding the meaning behind new Obamacare enrollment numbers

As the president renews his call for people -- especially African Americans and Latinos -- to enroll for insurance coverage, news outlets detail what is actually known about who has already signed up.

16 Feb 2014

Research provides new insight into the effect of misfolded proteins in neurodegenerative disorders

Research by the University of Southampton has provided new insight into the consequence of accumulated 'misfolded proteins' in neurodegenerative disorders, such as Prion and Alzheimer's disease.

16 Feb 2014

Major gaps persist in workplace protection against TB, HIV and hepatitis in South Africa

A large-scale survey of South African healthcare workers has revealed major gaps in workplace protection against tuberculosis, HIV and hepatitis, according to a University of British Columbia health researcher.

16 Feb 2014

New study documents frequency of EGFR mutations in lung adenocarcinoma in Asian population

Adenocarcinoma histology, female sex, never-smoking status, and Asian ethnicity have been considered the most important factors associated with EGFR mutations in non-small cell lung cancer and response to EGFR inhibitors. A recent study has found that, within the Asian population, the frequency of EGFR mutations associated with other demographic and clinical characteristics is higher than previously reported, even in patients with a history of smoking, suggesting that mutation testing should be done on a broader basis among Asian patients with advanced adenocarcinoma of the lung.

16 Feb 2014

People in northern latitudes have greater proportion of obesity-related bacteria in gut

People living in cold, northern latitudes have bacteria in their guts that may predispose them to obesity, according to a new study by researchers at the University of California, Berkeley, and the University of Arizona, Tucson.

15 Feb 2014

New treatments for depression on the horizon

New insights into the physiological causes of depression are leading to treatments beyond common antidepressants such as Prozac and Zoloft, researchers are reporting in the in the journal Current Psychiatry.

15 Feb 2014

Mobile compression device just as effective as blood thinners in preventing DVT after joint surgery

Research from The Shiley Center for Orthopaedic Research and Education at Scripps Clinic could change how patients are treated to prevent blood clots after joint replacement surgery. A study published as the lead article in the current issue of the Journal of Bone and Joint Surgery determined that after lower extremity joint replacement surgery a mobile compression device was just as effective as blood thinners in preventing deep vein thrombosis (DVT), but without negative side effects including bleeding complications.

15 Feb 2014

Attention modification programs help decrease overeating in obese children

Among the multiple factors that can cause obesity is an abnormal neurocognitive or behavioral response to food cues. The brain becomes wired to seek - and expect - greater rewards from food, which leads to unhealthful overeating.

15 Feb 2014

Heritable bipolar phenotypes pinned down

A large study has pinpointed brain and behavioural traits that are genetically influenced and associated with bipolar I disorder.

14 Feb 2014

‘Healthy living’ programme fails to lower BMI in overweight psychosis patients

A “healthy living” intervention focused on exercise and diet has failed to impact body mass index in overweight people with psychosis when evaluated in the setting of a randomised controlled trial.

14 Feb 2014

Research roundup: Examining readmissions; easing doctor burnout

Despite massive early IT problems, exchange enrollment is accelerating rapidly. While enrollment may not reach 7 million by the end of March, we expect at least 5 million to have enrolled by the close of the initial open-enrollment period. If enrollment falls far short, HHS could extend open enrollment for a fixed period to reach its 7 million target. ... We project that 5 million new beneficiaries will be covered by Medicaid and the Children's Health Insurance Program by the end of 2014. Medicaid managed-care enrollment of non-dual beneficiaries will increase by 20 percent from 2013 to 2014 and by 38 percent from 2013 to 2016. We expect that 75 percent of non-dual Medicaid beneficiaries will be covered by Managed Care Organizations starting in 2015, up from 63 percent in 2012 (Feb. 2014).

14 Feb 2014

Final stage of normal inflammatory process may be disrupted in patients with Alzheimer's disease

New research from Karolinska Institutet in Sweden shows that the final stage of the normal inflammatory process may be disrupted in patients with Alzheimer's disease. A study published in the journal Alzheimer's & Dementia shows that levels in the brain and cerebrospinal fluid of the molecules necessary for tissue recovery through the clearance of harmful inflammatory substances are lower than normal in patients with Alzheimer's disease. The study also showed association between the lower levels of these molecules with impaired memory function.

14 Feb 2014

NIAID awards Soligenix SBIR grant to further develop SGX943 for treatment of melioidosis

Soligenix, Inc., a clinical stage biopharmaceutical company focused on developing products to treat serious inflammatory diseases where there remains an unmet medical need, as well as developing several biodefense vaccines and therapeutics, announced today that the National Institute of Allergy and Infectious Diseases has awarded Soligenix a Small Business Innovation Research grant to support further preclinical development of SGX943 as a treatment for melioidosis.

14 Feb 2014

Teleflex announces launch of Rusch DispoLED Single-Use Fiber Optic Laryngoscope Handle

Teleflex Incorporated, a leading global provider of medical devices for critical care and surgery, has announced the launch of the Rusch® DispoLED™ Single-Use Fiber Optic Laryngoscope Handle — a cost-neutral way to combat cross-contamination infection risk during intubation.

14 Feb 2014

Zilver PTX randomized trial of paclitaxel-eluting stents for femoropopliteal disease demonstrates superior results

Four-year results of the Zilver PTX Randomized Controlled Trial of Paclitaxel-Eluting Stents for Femoropopliteal Disease continue to demonstrate consistent, superior results when compared to bare metal stents (BMS) and percutaneous transluminal angioplasty (PTA) in terms of primary patency, restenosis reduction and revascularization rates.

From COOK MEDICAL INC. 14 Feb 2014

First Edition: February 14, 2014

Today's early morning highlights from the major news organizations, including reports on the least expensive health insurance markets and efforts to set up skimpier plans under the health law.

14 Feb 2014

Medical News

Scientists discover novel antibody-based therapy that targets progression of kidney fibrosis

Findings underscore need to increase access to new treatments for minority groups, older patients

University of Adelaide research reveals new approach for bowel cancer treatment

Research findings have important implications for personalized treatment of alcohol abuse

Finding the meaning behind new Obamacare enrollment numbers

Research provides new insight into the effect of misfolded proteins in neurodegenerative disorders

Major gaps persist in workplace protection against TB, HIV and hepatitis in South Africa

New study documents frequency of EGFR mutations in lung adenocarcinoma in Asian population

People in northern latitudes have greater proportion of obesity-related bacteria in gut

New treatments for depression on the horizon

Mobile compression device just as effective as blood thinners in preventing DVT after joint surgery

Attention modification programs help decrease overeating in obese children

Heritable bipolar phenotypes pinned down

‘Healthy living’ programme fails to lower BMI in overweight psychosis patients

Research roundup: Examining readmissions; easing doctor burnout

Final stage of normal inflammatory process may be disrupted in patients with Alzheimer's disease

NIAID awards Soligenix SBIR grant to further develop SGX943 for treatment of melioidosis

Teleflex announces launch of Rusch DispoLED Single-Use Fiber Optic Laryngoscope Handle

Zilver PTX randomized trial of paclitaxel-eluting stents for femoropopliteal disease demonstrates superior results

First Edition: February 14, 2014

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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