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Study offers new insight into benefits of vitamin D in people with multiple sclerosis

In mice with a rodent form of multiple sclerosis (MS), vitamin D appears to block damage-causing immune cells from migrating to the central nervous system, offering a potential explanation for why the so-called "sunshine vitamin" may prevent or ease symptoms of the neurodegenerative disease, according to results of a study at Johns Hopkins.

9 Dec 2013

California exchange shares consumers' names without their consent

Officials with Covered California said they gave insurance agents the contact information of thousands of people who went online but didn't enroll in coverage as part of a pilot program to help people sign up by Dec. 23.

9 Dec 2013

ART safe and effective for treating combat-related symptoms of PTSD among veterans

Accelerated Resolution Therapy, or ART, is a brief, safe, and effective treatment for combat-related symptoms of post-traumatic stress disorder among veterans and U.S. service members, researchers at University of South Florida College of Nursing report in a new study. They found this newer treatment -- a combination of evidence-based psychotherapies and use of eye movements -- was shorter and more likely to be completed, than conventional therapies formally endorsed by the U.S. Department of Defense and the Veterans Administration.

9 Dec 2013

Equations help explain key parameters of stents that combat artherosclerosis

Coronary heart disease accounts for 18% of deaths in the United States every year. The disease results from a blockage of one or more arteries that supply blood to the heart muscle.

9 Dec 2013

New computational model explains how brain maintains balance between plasticity, stability

To learn new motor skills, the brain must be plastic: able to rapidly change the strengths of connections between neurons, forming new patterns that accomplish a particular task. However, if the brain were too plastic, previously learned skills would be lost too easily.

9 Dec 2013

Maryland's online insurance marketplace plagued by technical issues, discord

The director of the state exchange resigned Friday. Meanwhile, the web portal continues to be marked by operational difficulties that are undermining enrollment efforts.

9 Dec 2013

CRAB CTC enrolls first patient into inaugural cancer clinical trial

Cancer Research And Biostatistics today announced enrollment of the first patient into the inaugural clinical trial sponsored by its Clinical Trials Consortium. The CRAB CTC mission is to ensure rapid clinical testing of new and innovative cancer treatments, and is focusing on lung cancer as its first target. By engaging frontline treating oncologists to push the boundaries of patient care, the aim is to improve the standard of care and extend overall survival.

9 Dec 2013

Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation

Bone homeostasis requires precise balance between deposition of new bone by osteoblasts and resorption of old bone by osteoclasts. Bone diseases, including osteoporosis and rheumatoid arthritis, are the result of increased osteoclast activity and formation, which allows bone resorption to outpace deposition.

9 Dec 2013

Acetylon Pharmaceuticals presents positive interim data from two ricolinostat clinical trials at ASH 2013

Acetylon Pharmaceuticals, Inc., the leader in the development of selective histone deacetylase inhibitors for enhanced therapeutic outcomes, today announced that positive interim clinical data from the two proof-of-concept clinical trials with selective HDAC6 inhibitor, ricolinostat (ACY-1215), were presented at the 55th Annual Meeting of the American Society of Hematology in New Orleans, LA.

9 Dec 2013

Older people with diabetes are susceptible to nonfatal cardiovascular complications, hypoglycemic events

Cardiovascular complications and hypoglycemia (low blood sugar) were common nonfatal complications in adults 60 years of age and older with diabetes, according to a study published by JAMA Internal Medicine, a JAMA Network publication.

9 Dec 2013

FDA advisory committee backs Takeda's vedolizumab for treatment of ulcerative colitis, Crohn's disease

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals U.S.A., Inc., today announced that a joint panel of members from the Gastrointestinal Drugs and Drug Safety and Risk Management Advisory Committees of the United States Food and Drug Administration voted to recommend approval of Takeda's vedolizumab for the treatment of adults with moderately to severely active ulcerative colitis and Crohn's disease.

9 Dec 2013

Arrowhead reports Phase 1 study data on ARC-520 for treatment of chronic hepatitis B infection

Arrowhead Research Corporation, a biopharmaceutical company developing targeted RNAi therapeutics, today announced that COO and Head of R&D, Bruce Given, M.D., presented data on the Phase 1 clinical study of ARC-520, the company's clinical candidate for the treatment of chronic hepatitis B infection, at the HepDART 2013 conference being held on The Big Island, Hawaii.

9 Dec 2013

TAU researchers discover gene that may predict human responses to specific antidepressants

Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants, but they don't work for everyone. What's more, patients must often try several different SSRI medications, each with a different set of side effects, before finding one that is effective.

9 Dec 2013

UCI MIND researchers receive grant to develop and study patient-derived stem cell lines

Researchers at UC Irvine's Institute for Memory Impairments and Neurological Disorders have received a two-year, $600,000 grant from the National Institute on Aging to develop and study patient-derived stem cell lines.

9 Dec 2013

Lung cancer screening using low-dose CT reduces mortality in high-risk smokers

Previous evidence, including published National Lung Cancer Screening Trial (NLST) results, shows that computed tomography (CT) lung cancer screening significantly reduces lung cancer deaths in high risk patients*, and is appropriate, with careful patient selection and follow-up.

9 Dec 2013

New drug delivery system successfully treats advanced-stage ovarian cancer in mice

Scientists at Rutgers University have developed a targeted drug delivery system that they believe could make ovarian cancer more treatable and increase survival rates for the most deadly gynecological cancer in the United States.

9 Dec 2013

MUC5B protein plays key role in many lung-related ailments

An international team of researchers has zeroed in on a protein that plays a key role in many lung-related ailments, from seasonal coughing and hacking to more serious diseases such as MRSA infections and cystic fibrosis.

9 Dec 2013

Increased inflammation in prostate may predict reduced risk for cancer

Doctors at the North Shore-LIJ Health System have discovered that increased inflammation in the prostate may predict reduced risk for prostate cancer. The findings are published online in CANCER.

9 Dec 2013

Lawmakers close in on 'cease-fire' budget deal

Lawmakers are close to finding accord on a budget that would undo only a few parts of the government cuts known as "sequester." In addition, the proposed budget wouldn't lower the debt or change the costs involved with health care programs in addition to leaving other programs intact.

9 Dec 2013

Research explores epigenetic effects that contribute to psychiatric disorders in offspring

Advanced paternal age has been associated with greater risk for psychiatric disorders, such as schizophrenia and autism. With an increase in paternal age, there is a greater frequency of certain types of mutations that contribute to these disorders in offspring.

9 Dec 2013

Medical News

Study offers new insight into benefits of vitamin D in people with multiple sclerosis

California exchange shares consumers' names without their consent

ART safe and effective for treating combat-related symptoms of PTSD among veterans

Equations help explain key parameters of stents that combat artherosclerosis

New computational model explains how brain maintains balance between plasticity, stability

Maryland's online insurance marketplace plagued by technical issues, discord

CRAB CTC enrolls first patient into inaugural cancer clinical trial

Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation

Acetylon Pharmaceuticals presents positive interim data from two ricolinostat clinical trials at ASH 2013

Older people with diabetes are susceptible to nonfatal cardiovascular complications, hypoglycemic events

FDA advisory committee backs Takeda's vedolizumab for treatment of ulcerative colitis, Crohn's disease

Arrowhead reports Phase 1 study data on ARC-520 for treatment of chronic hepatitis B infection

TAU researchers discover gene that may predict human responses to specific antidepressants

UCI MIND researchers receive grant to develop and study patient-derived stem cell lines

Lung cancer screening using low-dose CT reduces mortality in high-risk smokers

New drug delivery system successfully treats advanced-stage ovarian cancer in mice

MUC5B protein plays key role in many lung-related ailments

Increased inflammation in prostate may predict reduced risk for cancer

Lawmakers close in on 'cease-fire' budget deal

Research explores epigenetic effects that contribute to psychiatric disorders in offspring

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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