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Senesco completes cohort 3 of SNS01-T Phase 1b/2a trial for multiple myeloma and lymphoma treatment

Senesco Technologies, Inc. reported today the completion of cohort 3 of its Phase 1b/2a clinical trial for its drug, SNS01-T, for the treatment of multiple myeloma and lymphoma. The Company has also received approval from its Data Review Committee to proceed to cohort 4, which is expected to require six evaluable patients.

5 Dec 2013

Study: Track-side noise may exceed 8,500% of person's daily recommended noise exposure

As an acoustical engineer, Craig Dolder - currently a graduate student at the University of Texas, Austin - knew that loud noises can damage hearing. Even so, when Canada's Formula 1 Grand Prix coincided with an Acoustical Society of America (ASA) meeting that he was attending in Montreal, Quebec, earlier this year, Dolder was drawn to the racetrack and the deafening roar of the Formula 1 engines.

5 Dec 2013

New, improved healthcare.gov gets praise, but problems persist

Administration officials lauded the website fixes and said that 750,000 users logged on Monday, but insurers continued to have concerns about the transfer of inaccurate data and automated subsidy calculations.

5 Dec 2013

Enrollment opens for IMO-8400 Phase 1/2 trial in patients with Waldenström's macroglobulinemia

Idera Pharmaceuticals, Inc., a clinical stage biopharmaceutical company developing a novel therapeutic approach for the treatment of autoimmune diseases and genetically defined forms of B-cell lymphoma, today announced that enrollment is open for a Phase 1/2 clinical trial of IMO-8400 in patients with Waldenström's macroglobulinemia, following acceptance of its Investigational New Drug application by the U.S. Food and Drug Administration.

5 Dec 2013

Poor sleep quality linked with mood disturbance and lower quality of life in people with obesity

A new study shows that poor sleep quality is strongly associated with mood disturbance and lower quality of life among people with extreme obesity.

5 Dec 2013

1.46 million enroll in Medicaid through health law exchanges

The Obama administration said Tuesday that more than 1.46 million people have been found eligible and signed up for Medicaid or the Children's Health Insurance Program in October.

5 Dec 2013

TYRX receives FDA clearance to market AIGISRx N Antibacterial Envelope

TYRX, Inc. announced today that it has received U.S. Food and Drug Administration clearance for expanded indications in marketing the AIGISRx N Antibacterial Envelope for use with spinal cord neuromodulators.

5 Dec 2013

States lead in health law insurance sign-up race

States operating their own insurance websites are leading the federal government in signing up people for health coverage. Though healthcare.gov, the federal website which serves the residents of 36 states, is working better for some, complicated cases still bewilder "navigators" -- and Texas has proposed new rules and background checks for the workers.

5 Dec 2013

New research offers fresh insights to drug designers searching for better pain treatments

In a technical tour de force, UC San Francisco scientists have determined, at near-atomic resolution, the structure of a protein that plays a central role in the perception of pain and heat.

5 Dec 2013

Mothers, but not fathers, exhibit symptoms of depression after the death of adult son

Mothers - but not fathers - exhibited symptoms of depression and experienced declines in overall health after the death of an adult son, while the death of a daughter had no such effect on either parent, according to one of the first studies to examine the impacts of the death of an adult child on parents aged 65 and older.

5 Dec 2013

MassBiologics gets FDA orphan drug designation for MBL-HCV1 antibody

MassBiologics of the University of Massachusetts Medical School has received an orphan drug designation from the U.S. Food and Drug Administration for MBL-HCV1, a monoclonal antibody developed to prevent hepatitis C virus recurrence in patients receiving a liver transplant.

5 Dec 2013

Blocking Cdh1 protein could accelerate development of new therapies targeting cancer

The laboratory of Marcos Malumbres, who is head of the Spanish National Cancer Research Centre's (CNIO) Cell Division & Cancer Group, working alongside Isabel Fari-as' team from the University of Valencia, shows, in a study published today in the journal Nature Communications, how in mice the elimination of the Cdh1 protein -a sub-unit of the APC/C complex, involved in the control of cell division-prevents cellular proliferation of rapidly dividing cells.

5 Dec 2013

Increasing education levels helps improve economic growth

A new study published in the journal Demography shows that improvements in education levels around the world have been key drivers of economic growth in developing countries that has previously been attributed to declines in fertility rates.

5 Dec 2013

Baicalin inhibits colistin sulfate-induced apoptosis of PC12 cells

Baicalin, a type of flavonoid extracted from the dried root of Scutellaria baicalensis georgi, has been shown to effectively inhibit cell apoptosis. Colistin sulfate, a cyclic cationic polypeptide antibiotic, has been shown to have renal and neurological side effects.

4 Dec 2013

UCLA researchers discover how prostate cancer stem cells evolve as the disease grows

UCLA researchers have discovered how prostate cancer stem cells evolve as the disease progresses, a finding that could help point the way to more highly targeted therapies.

4 Dec 2013

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

The first study of its kind, led by Melinda Sothern, PhD, CEP, Professor and Director of Behavioral and Community Health Sciences at LSU Health Sciences Center New Orleans School of Public Health, reveals that the same pro-inflammatory proteins linked to obesity and the metabolic syndrome in adults appear to protect children prior to puberty.

4 Dec 2013

BIDMC study shows carbon monoxide may have a role to play in treating cancer

In recent years, research has suggested that carbon monoxide, the highly toxic gas emitted from auto exhausts and faulty heating systems, can be used to treat certain inflammatory medical conditions. Now a study led by a research team at Beth Israel Deaconess Medical Center (BIDMC) shows for the first time that carbon monoxide may also have a role to play in treating cancer.

4 Dec 2013

Tet1 helps erase epigenetic imprints from genome ahead of egg, sperm development

A protein called Tet1 is partly responsible for giving primordial germ cells a clean epigenetic slate before developing into sperm and egg cells, according to a new study by researchers at Boston Children's Hospital.

4 Dec 2013

Researchers discover how PC7 protein affects certain types of cognitive performance

A team of Montr-al researchers at the IRCM led by Dr. Nabil G. Seidah, in collaboration with Dr. William C. Wetsel's team at Duke University in the United States, discovered that the protein PC7 plays a critical role in the brain by affecting certain types of cognitive performance such as anxiety, learning and emotional memory. Their results, recently published in the scientific journals Proceedings of the National Academy of Sciences (PNAS) and Nature, could have a significant impact on regulating behaviour related to anxiety disorders and trauma.

4 Dec 2013

Bipolar-specific disease management gives good returns

Diagnostic-specific management of bipolar II disorder is associated with significant clinical improvements, show findings that support the need for greater recognition of the condition.

4 Dec 2013

Medical News

Senesco completes cohort 3 of SNS01-T Phase 1b/2a trial for multiple myeloma and lymphoma treatment

Study: Track-side noise may exceed 8,500% of person's daily recommended noise exposure

New, improved healthcare.gov gets praise, but problems persist

Enrollment opens for IMO-8400 Phase 1/2 trial in patients with Waldenström's macroglobulinemia

Poor sleep quality linked with mood disturbance and lower quality of life in people with obesity

1.46 million enroll in Medicaid through health law exchanges

TYRX receives FDA clearance to market AIGISRx N Antibacterial Envelope

States lead in health law insurance sign-up race

New research offers fresh insights to drug designers searching for better pain treatments

Mothers, but not fathers, exhibit symptoms of depression after the death of adult son

MassBiologics gets FDA orphan drug designation for MBL-HCV1 antibody

Blocking Cdh1 protein could accelerate development of new therapies targeting cancer

Increasing education levels helps improve economic growth

Baicalin inhibits colistin sulfate-induced apoptosis of PC12 cells

UCLA researchers discover how prostate cancer stem cells evolve as the disease grows

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

BIDMC study shows carbon monoxide may have a role to play in treating cancer

Tet1 helps erase epigenetic imprints from genome ahead of egg, sperm development

Researchers discover how PC7 protein affects certain types of cognitive performance

Bipolar-specific disease management gives good returns

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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