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Study identifies genomic regions associated with cholera susceptibility

An international research team has used a novel approach to identify genetic factors that appear to influence susceptibility to cholera. The findings by investigators from Massachusetts General Hospital (MGH), the Broad Institute and the International Center for Diarrh-al Disease Research, Bangladesh (ICDDR,B) indicate the importance of pathways involved in regulating water loss in intestinal cells and of the innate immune system in the body's response to the bacteria that causes cholera, which affects from 3 to 5 million people each year and causes more than 100,000 deaths.

4 Jul 2013

Expertly written, practical handbook of pediatric thrombosis and hemostasis

An expertly written, practical handbook for the clinical assessment and management of children with inherited or acquired bleeding and clotting disorders

4 Jul 2013

CEA-Leti receives €1M from bpifrance to accelerate the development of liver-cancer detection system

CEA-Leti announced today €1 million in funding from bpifrance to accelerate preclinical development of a liver-cancer detection system called LipImage 815™.

4 Jul 2013

Duke researchers solve some mysteries related to the use of aspirin

Aspirin has been widely used for more than 50 years as a common, inexpensive blood thinner for patients with heart disease and stroke, but doctors have little understanding of how it works and why some people benefit and others don't.

4 Jul 2013

Businesses welcome enforcement delay for the health overhaul's employer mandate

Large employers, many of which already provide coverage to full-time workers, cheered the news because it would relieve them of complex new reporting requirements. Businesses with fewer than 50 employees are not subject to the coverage mandate.

4 Jul 2013

Researchers find that hot flashes take heavier toll on quality of life in HIV-infected women

Women with HIV are living longer, so more are entering menopause. As they do, they suffer more severe hot flashes than women without HIV, and their hot flashes take a heavier toll on their quality of life and daily functioning, found researchers at Massachusetts General Hospital.

4 Jul 2013

Study reveals health benefits of a good night's sleep

A good night's sleep can increase the benefit of exercise, healthy diet, moderate alcohol consumption and non-smoking in their protection against cardiovascular disease (CVD), according to results of a large population follow-up study. Results showed that the combination of the four traditional healthy lifestyle habits was associated with a 57% lower risk of cardiovascular disease (fatal and non-fatal) and a 67% lower risk of fatal events. But, when "sufficient sleep" (defined as seven or more hours a night) was added to the other four lifestyle factors, the overall protective benefit was even further increased - and resulted in a 65% lower risk of composite CVD and a 83% lower risk of fatal events.

4 Jul 2013

New study finds inherited genetic contribution in autism with intellectual disability

Researchers are striving to understand the different genetic structures that underlie at least a subset of autism spectrum disorders. In cases where the genetic code is in error, did that happen anew in the patient, perhaps through mutation or copying error, or was it inherited? A new study in the American Journal of Human Genetics finds evidence that there may often be a recessive, inherited genetic contribution in autism with significant intellectual disability.

4 Jul 2013

Roche introduces new metabolite tests for cell fermentation analytics

Roche today announced the launch of new metabolite-testing reagent sets to determine the concentration of iron and phosphate, two parameters relevant for cell growth and productivity during fermentation processes.

4 Jul 2013

Prana gets Austin HREC approval for 12-month open label extension study of PBT2 in Alzheimer’s patients

Prana Biotechnology today announced that it has received approval from the Austin Health Human Research Ethics Committee (HREC) to commence a 12-month open label extension study with Alzheimer’s Disease patients participating in Prana’s IMAGINE trial.

4 Jul 2013

UnitedHealthcare to again review Tricare specialty care referrals

The Department of Defense will once again allow UnitedHealthcare to review and authorize every specialty care referral in Tricare. The insurer also notified California that it will no longer sell individual insurance in that state.

4 Jul 2013

Gerovital H3 may be making a comeback, warns BUSM researcher

Despite it being more than 30 years since the "fountain of youth drug" Gerovital H3 was banned in the United States, it may be making a comeback. In an editorial published in this month's Journal of the American Geriatrics Society BUSM researcher Thomas Perls, MD, points out that a few U.S.-based anti-aging and longevity clinics have begun to advertise Gerovital H3 in pill form and as intravenous infusions despite the fact that the U.S. Food and Drug Administration banned it in 1982.

4 Jul 2013

EyeTechCare's EyeOP1 device to be installed in four healthcare facilities in France

EyeTechCare SA, which develops non-invasive therapeutic medical devices for the ophthalmology market based on the use of ultrasound, today announces that its EyeOP1 device is to be installed in a number of hospitals in France, namely Lille University Hospital, Grenoble University Hospital and the Quinze-Vingts and Saint-Joseph hospitals in Paris. The first use of this device for the routine treatment of glaucoma patients is slated from July onwards.

4 Jul 2013

Updated EULAR recommendations for management of rheumatoid arthritis

The European League Against Rheumatism has released updated recommendations for the management of RA. According to this latest guidance, treatment with disease-modifying anti-rheumatic drugs should be initiated as soon as a diagnosis of RA is made, with the aim of reaching a target of remission or low disease activity in every patient.

4 Jul 2013

Study shows possible biological cause of narcolepsy

In 2000, researchers at the UCLA Center for Sleep Research published findings showing that people suffering from narcolepsy, a disorder characterized by uncontrollable periods of deep sleep, had 90 percent fewer neurons containing the neuropeptide hypocretin in their brains than healthy people.

4 Jul 2013

State exchanges largely unaffected by delay in employer mandate

Officials in California and Minnesota say that neither the timing, nor the content of insurance coverage offered in their new online insurance marketplaces will be affected by the administration's decision to suspend enforcement of penalties on large employers until 2015.

4 Jul 2013

Research shows mutations in FAM190A gene may contribute to chromosomal instability in cancer

Johns Hopkins cancer scientists have discovered that a little-described gene known as FAM190A plays a subtle but critical role in regulating the normal cell division process known as mitosis, and the scientists' research suggests that mutations in the gene may contribute to commonly found chromosomal instability in cancer.

4 Jul 2013

ERYTECH reports fast take-off of GRASPA Phase IIb trial in patients with acute myeloid leukemia

ERYTECH, a French biopharmaceutical company that develops innovative treatments for acute leukemia and other oncology indications with unmet medical needs, announces a fast take-off of its Phase IIb study in Acute Myeloid Leukemia.

4 Jul 2013

MGN1703 drug provides a new treatment approach to colorectal cancer

New data on an emerging treatment that aims to fight colorectal cancer by stimulating the immune system have been presented at the ESMO 15th World Congress on Gastrointestinal Cancer.

4 Jul 2013

Employers worry they'll pay bill for those exempt from contraceptive mandate

Businesses are concerned that non-religious employers will end up covering the bill for religious groups that refuse to pay for contraception for their employees. Meanwhile, church leaders continue their push to broaden the exemption from the contraception coverage rule.

4 Jul 2013