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Transition, Lilly amend agreement to address future development of TT-401

Transition Therapeutics Inc. announced that Eli Lilly and Company has exercised its option to assume all development and commercialization rights to type 2 diabetes drug candidate TT-401.

17 Jun 2013

STAAR Surgical to market Visian ICL with CentraFLOW technology in Korea, Argentina

STAAR Surgical Company, a leading developer, manufacturer and marketer of minimally invasive ophthalmic products, today announced that it has received regulatory approvals to market its Visian Implantable Collamer Lens with CentraFLOW technology from the KFDA in Korea and the ANMAT in Argentina.

17 Jun 2013

Genmab, ADC Therapeutics agree to develop new antibody-drug conjugate product

Genmab A/S and ADC Therapeutics Sarl, announced today an agreement to develop a new antibody-drug conjugate product combining Genmab's HuMax-TAC antibody and ADC Therapeutics' PBD-based warhead and linker technology.

17 Jun 2013

NGM, MedImmune partner to develop novel therapeutics for treatment of diabetes and obesity

NGM Biopharmaceuticals, Inc. and MedImmune, the global biologics research and development arm of AstraZeneca, announced today that they have entered into an exclusive agreement to discover, develop and commercialize novel therapeutics from NGM's enteroendocrine cell program for the treatment of type 2 diabetes and obesity.

17 Jun 2013

Orexo announces dosing of first patient with Zubsolv in phase III clinical study

Orexo AB announces today that the first patient has been dosed with Zubsolv in a phase III study for a new clinical indication for Zubsolv.

17 Jun 2013

Researchers produce first genome-wide investigation of cap-independent translation

Because of their central importance to biology, proteins have been the focus of intense research, particularly the manner in which they are produced from genetically coded templates-a process commonly known as translation. While the general mechanism of translation has been understood for some time, protein synthesis can initiate by more than one mechanism. One of the least well understood mechanisms is known as cap-independent translation.

17 Jun 2013

Athera receives support from FP7 for development of fully human antibody PC-mAb

Athera Biotechnologies AB today announced that future development costs of its fully human antibody PC-mAb up until proof-of-concept will be co-funded by the European Union's Seventh Framework Programme for Research (FP7) through a collaborative research grant. Karolinska Development AB owns 65% of Athera Biotechnologies AB.

17 Jun 2013

Minority children with autism less likely to have received subspecialty care or procedures, study finds

A study from investigators at MassGeneral Hospital for Children found that African-American or Hispanic children diagnosed with autism were significantly less likely than white children to have received subspecialty care or procedures related to conditions that often accompany autism spectrum disorders.

17 Jun 2013

New study finds that sibling aggression associated with worse mental health

Fights between siblings - from toy-snatching to clandestine whacks to being banished from the bedroom - are so common they're often dismissed as simply part of growing up. Yet a new study from researchers at the University of New Hampshire finds that sibling aggression is associated with significantly worse mental health in children and adolescents.

17 Jun 2013

European Commission amends marketing authorisation for Celgene's REVLIMID

Celgene International Sàrl was today notified that the European Commission has amended the marketing authorisation for REVLIMID. This decision means that REVLIMID is now approved to treat patients with transfusion-dependent anaemia due to low or intermediate-1 risk myelodysplastic syndromes associated with an isolated deletion 5q cytogenetic abnormality when other therapeutic options are insufficient or inadequate.

17 Jun 2013

Mayo Clinic researchers say that adolescents with chronic pain need to avoid medical marijuana

Adolescents can have chronic pain, just like adults. It can interfere with normal development, making it difficult for teens to attend school, socialize or be physically active, the cause may be hard to find, and medications are sometimes tried without success. As patients, their parents and physicians search for solutions, there is one increasingly available option they should avoid, Mayo Clinic researchers say: medical marijuana.

17 Jun 2013

Scientists find that psychiatric disorders may be linked to protein involved in memory formation

Researchers have discovered a pathway by which the brain controls a molecule critical to forming long-term memories and connected with bipolar disorder and schizophrenia.

17 Jun 2013

Mount Sinai researchers present several new studies at ENDO 2013

Researchers from the Icahn School of Medicine at Mount Sinai will present several new studies at ENDO 2013, The Endocrine Society's Annual Meeting & Expo from June 15-18 in San Francisco.

17 Jun 2013

Investigators recruit subjects for Boston Children's Hand Transplant Program

Boston Children's Hospital today announced that investigators are now recruiting subjects for the world's first pediatric hand transplant program. The Boston Children's Hand Transplant Program, led by principal investigator Amir Taghinia, MD, and William Harmon, MD, is a research-based program that will offer bi-lateral hand transplants for children living without two functioning hands.

17 Jun 2013

Researchers identify genetic mutation responsible for MDP Syndrome

National Paracycling Champion Tom Staniford has an extremely rare condition which, until now, has puzzled his doctors. He is unable to store fat under his skin - yet has type 2 diabetes - and suffered hearing loss as a child. Now, thanks to advances in genome sequencing, an international research team led by the University of Exeter Medical School has identified Tom's condition and pinpointed the single genetic mutation that causes it.

17 Jun 2013

Ibrutinib monotherapy shows efficacy in patients with MCL or DLBCL

Pharmacyclics, Inc. today announced the results of two separate Phase 2 studies suggesting that ibrutinib, an investigational oral Bruton's tyrosine kinase inhibitor, showed efficacy when used as a monotherapy in patients with relapsed/refractory mantle cell lymphoma or diffuse large B-cell lymphoma.

17 Jun 2013

Eli Lilly, BIPI support ADA's call for independent review of incretin-based therapies

Boehringer Ingelheim Pharmaceuticals, Inc. and Eli Lilly and Company support the American Diabetes Association call for an independent review of the safety data of incretin-based therapies.

17 Jun 2013

Scientists develop new tool for analyzing and characterizing aspects of the brain's neural circuitry

Scientists at the University of Massachusetts Medical School have developed a novel transgenic system which allows them to remotely activate individual brain cells in the model organism Drosophila using ambient temperature.

17 Jun 2013

New research reports that UnaG protein could lead to new liver test

Many scientists dream of making a single discovery that provides fundamental insight into nature, may be used to help save human lives, and can assist in the preservation of an endangered species. In new research reported in the journal Cell, a Japanese team is on the verge of accomplishing this nearly impossible feat.

17 Jun 2013

Bristol-Myers Squibb, AstraZeneca release statement on ADA's efforts toward incretin-based therapies

Earlier this week, the American Diabetes Association called for manufacturers of incretin-based therapies to make patient-level data available from clinical trials for an independent analysis of pancreatic safety.

17 Jun 2013

Medical News

Transition, Lilly amend agreement to address future development of TT-401

STAAR Surgical to market Visian ICL with CentraFLOW technology in Korea, Argentina

Genmab, ADC Therapeutics agree to develop new antibody-drug conjugate product

NGM, MedImmune partner to develop novel therapeutics for treatment of diabetes and obesity

Orexo announces dosing of first patient with Zubsolv in phase III clinical study

Researchers produce first genome-wide investigation of cap-independent translation

Athera receives support from FP7 for development of fully human antibody PC-mAb

Minority children with autism less likely to have received subspecialty care or procedures, study finds

New study finds that sibling aggression associated with worse mental health

European Commission amends marketing authorisation for Celgene's REVLIMID

Mayo Clinic researchers say that adolescents with chronic pain need to avoid medical marijuana

Scientists find that psychiatric disorders may be linked to protein involved in memory formation

Mount Sinai researchers present several new studies at ENDO 2013

Investigators recruit subjects for Boston Children's Hand Transplant Program

Researchers identify genetic mutation responsible for MDP Syndrome

Ibrutinib monotherapy shows efficacy in patients with MCL or DLBCL

Eli Lilly, BIPI support ADA's call for independent review of incretin-based therapies

Scientists develop new tool for analyzing and characterizing aspects of the brain's neural circuitry

New research reports that UnaG protein could lead to new liver test

Bristol-Myers Squibb, AstraZeneca release statement on ADA's efforts toward incretin-based therapies

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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