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$Exercise interventions in childhood are associated with lower fracture risks in old age$

Exercise interventions in childhood are associated with lower fracture risks in old age

Get out there and regularly kick that soccer ball around with your kids, you may be helping them prevent a broken hip when they are older, say researchers presenting their work at the American Orthopaedic Society for Sports Medicine's (AOSSM) Specialty Day in Chicago, IL.

25 Mar 2013

arGEN-X advances ARGX-112 into formal preclinical development

arGEN-X, a clinical stage biopharmaceutical company specialized in the discovery and development of highly differentiated human monoclonal antibody therapeutics, announces that it has progressed ARGX-112, its fourth therapeutic candidate, into formal preclinical development.

25 Mar 2013

Scientists develop new chemo drug that fights cancer without impacting fertility

A new gentler chemotherapy drug in the form of nanoparticles has been designed by Northwestern Medicine- scientists to be less toxic to a young woman's fertility but extra tough on cancer. This is the first cancer drug tested while in development for its effect on fertility using a novel in vitro test.

25 Mar 2013

Japan's MHLW approves XELJANZ for treatment of adults with rheumatoid arthritis

Pfizer Inc. announced today that the Japanese Ministry of Health, Labor and Welfare has approved XELJANZ (tofacitinib citrate) for the treatment of adults with rheumatoid arthritis who have had an inadequate response to existing therapies.

25 Mar 2013

BioCryst starts BCX4161 Phase 1 clinical trial for treatment of hereditary angioedema

BioCryst Pharmaceuticals, Inc. announced the initiation of a Phase 1 clinical trial to evaluate the safety, pharmacokinetics and pharmacodynamics of orally-administered BCX4161 in healthy volunteers.

25 Mar 2013

High-fiber foods can fight inflammation

Inflammation is the body's normal response to injury. While it may be a natural defense system, it can lead to disease development if it becomes chronic. A University of Alabama at Birmingham (UAB) expert says one way to fight inflammation is with food.

25 Mar 2013

Study shows teen childbirth rates are more than 20% for abused and neglected teens

Abused or neglected teenage girls become teen mothers at nearly five times the national rate of teen motherhood. A new Cincinnati Children's Hospital Medical Center study, published in the eFirst pages of the journal Pediatrics, shows that teen childbirth rates are more than 20 percent for abused and neglected teens.

25 Mar 2013

First Edition: March 25, 2013

Today's headlines include reports about the continuing outlook for progress on the federal budget as well as a variety of stories related to the health law's implementation.

25 Mar 2013

Newly discovered molecule could form the basis of anti-malaria drugs

An international study, involving researchers from Griffith University's Eskitis Institute, has discovered a molecule which could form the basis of powerful new anti-malaria drugs.

25 Mar 2013

Actavis settles patent litigation with AstraZeneca over generic version of Crestor

Actavis, Inc., a leading specialty pharmaceutical company, today announced that is has reached a settlement agreement with AstraZeneca resolving outstanding patent litigation related to Actavis' generic version of rosuvastatin calcium 5, 10, 20 and 40 mg tablets, the generic version of Crestor tablets, as well as Actavis' rosuvastatin zinc alternate salt product.

25 Mar 2013

Study shows why certain drugs that interact with serotonin receptors have harmful effects

A team including scientists from The Scripps Research Institute (TSRI), the University of North Carolina at Chapel Hill and the Chinese Academy of Sciences has determined and analyzed the high-resolution atomic structures of two kinds of human serotonin receptor.

25 Mar 2013

Konzo's harm goes beyond devastating physical effects

The harm done by konzo - a disease overshadowed by the war and drought it tends to accompany - goes beyond its devastating physical effects to impair children's memory, problem solving and other cognitive functions.

25 Mar 2013

MIT biology professor named Pew's Biomedical Researcher of the Month

Biologist Mary Gehring, Ph.D. is The Pew Charitable Trusts' featured biomedical researcher of the month for her creative research on epigenetics in plants.

25 Mar 2013

Scientists identify potential treatment for idiopathic pulmonary fibrosis

Investigators at the University of Alabama at Birmingham (UAB) have unlocked another piece of the puzzle surrounding idiopathic pulmonary fibrosis, an often fatal lung disease with no cure and no effective treatments.

25 Mar 2013

Researchers study gene variants that bear signature for inflammatory disease susceptibility

In new research published in the April 4, 2013 issue of The American Journal of Human Genetics, researchers from Brigham and Women's Hospital demonstrate that some variants in our genes that could put a person at risk for inflammatory diseases such as multiple sclerosis, Crohn's disease or rheumatoid arthritis, have been the target of natural selection over the course of human history.

25 Mar 2013

Researchers expand hematopoietic stem cells for bone marrow transplantation

More than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation -- a critical step towards producing a large supply of blood stem cells needed to restore a healthy blood system.

25 Mar 2013

$Immune system responds to fracture in similar way as to infection$

Immune system responds to fracture in similar way as to infection

Researchers at Charité - Universitätsmedizin Berlin have succeeded in demonstrating an association between delayed bone fracture healing and increased concentration of specific immune cells in the blood of the patient.

25 Mar 2013

Research may offer clues to why esophageal adenocarcinomas rates have increased rapidly

During the past 30 years, the number of patients with cancers that originate near the junction of the esophagus and stomach has increased approximately 600 percent in the United States. The first extensive probe of the DNA of these esophageal adenocarcinomas has revealed that many share a distinctive mix-up of letters of the genetic code, and found more than 20 mutated genes that had not previously been linked to the disease.

25 Mar 2013

New guidance highlights risk factors and treatments for osteoporosis in postmenopausal women

A new Guidance recently published by the European Society for Clinical and Economic Aspects of Osteoporosis (ESCEO) and the International Osteoporosis Foundation (IOF) reflects the most current advances in the diagnosis and management of osteoporosis, the 'silent disease' which affects up to one in two postmenopausal women.

25 Mar 2013

Healthy lifestyle may help prolong lives of individuals with chronic kidney disease

Certain lifestyle factors—such as not smoking, getting regular physical activity, and avoiding a low body weight—may help prolong the lives of individuals with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

25 Mar 2013

Medical News

Exercise interventions in childhood are associated with lower fracture risks in old age

arGEN-X advances ARGX-112 into formal preclinical development

Scientists develop new chemo drug that fights cancer without impacting fertility

Japan's MHLW approves XELJANZ for treatment of adults with rheumatoid arthritis

BioCryst starts BCX4161 Phase 1 clinical trial for treatment of hereditary angioedema

High-fiber foods can fight inflammation

Study shows teen childbirth rates are more than 20% for abused and neglected teens

First Edition: March 25, 2013

Newly discovered molecule could form the basis of anti-malaria drugs

Actavis settles patent litigation with AstraZeneca over generic version of Crestor

Study shows why certain drugs that interact with serotonin receptors have harmful effects

Konzo's harm goes beyond devastating physical effects

MIT biology professor named Pew's Biomedical Researcher of the Month

Scientists identify potential treatment for idiopathic pulmonary fibrosis

Researchers study gene variants that bear signature for inflammatory disease susceptibility

Researchers expand hematopoietic stem cells for bone marrow transplantation

Immune system responds to fracture in similar way as to infection

Research may offer clues to why esophageal adenocarcinomas rates have increased rapidly

New guidance highlights risk factors and treatments for osteoporosis in postmenopausal women

Healthy lifestyle may help prolong lives of individuals with chronic kidney disease

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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