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Early lymphoid progenitors thrive in an osteoblastic niche: Study

The Children's Medical Center Research Institute at UT Southwestern has deepened the understanding of the environment within bone marrow that nurtures stem cells, this time identifying the biological setting for specialized blood-forming cells that produce the infection-fighting white blood cells known as T cells and B cells.

25 Feb 2013

Researchers to present new results for Merck's allergy immunotherapy tablets at AAAAI meeting

Merck, known as MSD outside the United States and Canada, today announced that researchers will present new data analyses of the safety and efficacy of the company's investigational allergy immunotherapy tablets (AITs) for ragweed pollen (Ambrosia artemisiifolia) and grass pollen (Phleum pratense) at the 2013 American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting.

25 Feb 2013

Distinct bone marrow niches can nurture different types of blood stem cells

In research that could one day improve the success of stem cell transplants and chemotherapy, scientists have found that distinct niches exist in bone marrow to nurture different types of blood stem cells.

25 Feb 2013

Better representation of elderly patients in phase III trials can improve evidence-based treatment

The median age of patients diagnosed with advanced non-small-cell lung cancer (NSCLC) has steadily increased over the recent years and is presently 70 years. Despite this, the elderly are significantly underrepresented in clinical trials.

25 Feb 2013

Dana-Farber launches iPhone app that helps fight cancer

Dana-Farber Cancer Institute has launched a free, easy-to-use iPhone app that provides recipes and nutrition information that can be searched by cancer patients in accordance with their needs.

25 Feb 2013

Mindray fourth quarter net revenues increase 19.7% to $316.1 million

Mindray Medical International Limited, a leading developer, manufacturer and marketer of medical devices worldwide, announced today its selected unaudited financial results for the fourth quarter and full year ended December 31, 2012.

From Mindray 25 Feb 2013

Genetic testing strategy for familial high cholesterol questioned

Current testing strategies for the families of patients with familial hypercholesterolemia may not be an efficient use of health resources, suggest study results published in The Lancet.

25 Feb 2013

Multi-dimensional physical activity assessment recommended

Research suggests that assessment of physical activity level should evaluate a person’s overall level of moderate or vigorous activity as well as their amount of sedentary time to get an accurate estimate.

25 Feb 2013

Screening of children with LUT dysfunction needs refining

Physicians should include screening for psychosocial comorbidities and obesity when evaluating children with lower urinary tract dysfunction, say researchers.

25 Feb 2013

WOEST supports clopidogrel only in PCI patients on anticoagulation

Publication of the WOEST trial results reaffirm the study’s major finding that antiplatelet therapy with clopidogrel alone is preferable to the use of both aspirin and clopidogrel in patients undergoing percutaneous coronary intervention who are receiving oral anticoagulant therapy.

25 Feb 2013

Antioxidant boosts liver transplant outcomes

Infusion of N-acetylcysteine in liver donors can significantly improve the outcome of transplantation, research shows.

25 Feb 2013

Adjustable shunt effectively alleviates hydrocephalus pressure

Using a shunt with an adjustable Strata valve that is initially set at the highest setting so it can be titrated down is a worthwhile approach to treat idiopathic normal pressure hydrocephalus.

25 Feb 2013

Symptoms poor guide to testing for juvenile Huntington disease

The onset or presentation of specific clinical features that are typical of juvenile Huntington’s Disease (JHD) do not help physicians to diagnose the condition without genetic testing.

25 Feb 2013

Oral health in elderly Chileans improving, but disparities remain

Oral health makes a significant contribution to the general wellbeing of older people, a survey of Chilean over-60s has found.

25 Feb 2013

CT angiography uncovers cardiovascular disease risk

Computed tomography angiography can warn of the likelihood for major adverse cardiovascular events in patients suspected of having coronary artery disease in the absence of medically modifiable risk factors, research shows.

25 Feb 2013

Mental health risk increased in children with atopic dermatitis

Results from a US study suggest that children with atopic dermatitis (AD) are at significantly increased risk for mental health disorders.

25 Feb 2013

CHADS scores possibilities extend beyond atrial fibrillation

The CHADS-based risk scores can predict long-term vascular outcomes and mortality in patients with stroke who do not have atrial fibrillation, research suggests.

25 Feb 2013

Visual processing clue to schizophrenia risk

An element of the event-related potential response to visual stimuli is impaired in patients with prodromal symptoms of schizophrenia, research suggests.

25 Feb 2013

Community health team improves diabetes control in Polynesian community

A team of community health workers has been able to improve control of Type 2 diabetes in a group of individuals from American Samoa – a medically underserved territory with a high prevalence of obesity, diabetes, and other cardiovascular risk factors, report researchers.

25 Feb 2013

ABCDE criteria non optimal for pediatric melanoma diagnosis

Conventional criteria for diagnosing melanoma may not be accurate in children and adolescents, suggest results published in the Journal of the American Academy of Dermatology.

25 Feb 2013