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Anxiety positively linked to physical activity in COPD patients

Higher levels of anxiety are associated with increased physical activity in patients with chronic obstructive pulmonary disease, US researchers report.

8 Feb 2013

Familial psychosis risk linked to prefrontal dopamine dysfunction

People at familial risk for psychosis have attenuated dopamine stress modulation in the ventromedial prefrontal cortex, according to a recent in vivo imaging study.

8 Feb 2013

White matter injury common after aortic arch surgery in infants

Diagnostic category is the strongest predictor for postoperative white matter injury in infants undergoing surgery for congenital heart disease, say researchers.

8 Feb 2013

Melatonin viable alternative for REM sleep behavior disorder treatment

Clonazepam and melatonin appear to be equally effective for the treatment of rapid eye movement sleep behavior disorder symptoms, although melatonin may be better tolerated, a naturalistic clinical study shows.

8 Feb 2013

Intravitreal ranibizumab shows little benefit after hemorrhage

Ranibizumab given intravitreally offers no clear benefit in the treatment of vitreous hemorrhage due to proliferative diabetic retinopathy, a randomized clinical trial indicates.

8 Feb 2013

Tumor necrosis factor receptor 2 involved in renal decline in diabetes

Researchers have found that circulating levels of tumor necrosis factor receptor 2 are independently associated with the development of chronic kidney disease in nonobese Japanese patients with Type 2 diabetes.

8 Feb 2013

Milk thistle constituent shows promising skin protection properties

Silibinin, a key component of milk thistle seeds, can help protect against skin damage caused by ultraviolet B radiation, show study findings published in Molecular Carcinogenesis.

8 Feb 2013

Education and response programs reduce opioid overdose deaths

Results from a US study suggest that a state-supported program of overdose education and nasal naloxone distribution for potential bystanders can help reduce opioid-related overdose deaths.

8 Feb 2013

eGFR ‘powerful’ operative risk gauge

Patients’ estimated glomerular filtration rate is highly predictive of their risk for dying after surgery, shows a systematic review and meta-analysis.

8 Feb 2013

HIV prevention: don’t just target serodiscordant couples

A large proportion of heterosexual HIV transmission in sub-Saharan Africa occurs among stable couples who have sexual partners outside of their relationship, shows research published in The Lancet.

8 Feb 2013

Higher arm reading ‘overestimates true BP’

Using the higher of left and right arm single blood pressure readings taken sequentially leads to an overestimation of patients’ “true” level as determined by ambulatory monitoring, UK researchers warn.

8 Feb 2013

Oral eosinophilic ulcers ‘a self-limiting, reactive condition’

A review of patients with oral eosinophilic ulcers suggests that the lesions should be considered a reactive, local condition rather than a CD30+ lymphoproliferative disorder.

8 Feb 2013

Novel combination of ibrutinib and bortezomib could be effective new therapy for blood cancers

Laboratory experiments conducted by scientists at Virginia Commonwealth University Massey Cancer Center suggest that a novel combination of the drugs ibrutinib and bortezomib could potentially be an effective new therapy for several forms of blood cancer, including diffuse large B-cell lymphoma (DLBCL) and mantle cell lymphoma (MCL).

7 Feb 2013

Conference attendees express concern over growing burden of NCDs

Inter Press Service reports on "a conference organized by the International Federation of Pharmaceutical Manufacturers and Associations (IFPMA) on World Cancer Day [February 4] in Geneva," during which experts warned about the growing burden of non-communicable diseases (NCDs) -- "cancer, heart disease, diabetes and chronic respiratory diseases, among others" -- especially in low- and middle-income countries.

7 Feb 2013

Study finds two biomarkers of acute kidney injury

Acute kidney injury strikes large numbers of hospitalized patients, including those with no prior kidney-related illness, and is one of the most costly and deadly conditions affecting critically ill patients.

7 Feb 2013

Uganda's childhood immunization programs face challenges, IRIN reports

"Inadequate funding, a shortage of health staff, and poor adherence to vaccination schedules are some of the reasons for declining immunization levels in Uganda, which experts say threatens efforts to reduce preventable deaths among children," IRIN reports.

7 Feb 2013