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Second trimester HG demands vigilance

Women who experience hyperemesis gravidarum during the second trimester have an increased risk for certain birth complications associated with placental abruption, study results show.

5 Feb 2013

Caution on COX inhibitor use in preterm infants

Very-low-birthweight preterm infants with thrombocytopenia treated with cyclooxygenase inhibitors are at an increased risk for intracerebral hemorrhage, particularly if they have decreased platelet levels, research shows.

5 Feb 2013

Restricting gifts in medical school influences future prescribing behavior

US physicians who attended a medical school with a policy restricting acceptance of gifts from pharmaceutical companies are less likely to prescribe newly marketed drugs than physicians who were not exposed to such restrictions during training, according to research published in the BMJ.

5 Feb 2013

Seven factors rule out CT for children with abdominal injury

Research shows that children presenting with abdominal injury at an emergency department who lack seven key factors are extremely unlikely to have an injury requiring acute intervention and therefore do not require computed tomography scanning.

5 Feb 2013

Detection of B cells may predict graft-versus-host disease

The ability to detect B cells specific to the DEAD box protein may help predict the development of chronic graft-versus-host disease in male recipients of female hematopoietic cells, according to recent findings.

5 Feb 2013

Advanced care planning improves end-of-life care

Advance care planning for older adults results in improved quality of care at the end of life, with less in-hospital death and the increased use of hospice services, the results of a study indicate.

5 Feb 2013

Subclinical hypothyroidism not prognostic in thyroid carcinoma

Subclinical hypothyroidism is not an independent predictor for clinical outcomes in patients with papillary thyroid carcinoma, research shows.

5 Feb 2013

Location of altered brain metabolite levels found in bipolar I patients

Bipolar I disorder patients have increased phospholipid levels in the thalami and increased N-acetyl-aspartate levels in the left hippocampus compared with healthy individuals, a team of investigators has discovered.

5 Feb 2013

Social cognition and negative symptoms scores reveal schizophrenia subgroups

Schizophrenia patients may be classified into three distinct subgroups, based on levels of social cognition and negative symptoms, that are associated with differences in community integration and quality of life, US study findings suggest.

5 Feb 2013

‘Urgent need’ for primary care pneumonia diagnosis tools

While family doctors can exclude pneumonia with a high level of accuracy, they can only identify around a third of radiographically confirmed cases, research shows.

5 Feb 2013

UCSD receives $3.4M NIMH grant to study successful aging in HIV-infected adults

The National Institute of Mental Health has awarded a $3.4 million grant to a team of researchers at the University of California, San Diego School of Medicine to study successful aging in HIV-infected adults. HIV is a serious, chronic, medical disease that affects the lives of more than one million Americans.

5 Feb 2013

Regular exercise reduces development of painful diabetic neuropathy in animals

Regular exercise reduces the development of painful diabetic neuropathy in animals—apparently related to increased expression of a protective substance called "heat shock protein" 72 (Hsp72), reports an experimental study in the February issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

5 Feb 2013

GLP-1 receptor agonists associated with reduced BMI in adolescents with severe obesity

Preliminary evidence from a clinical trial suggests that treatment with glucagon-like peptide-1 (GLP-1) receptor agonists was associated with reduced body mass index and body weight in adolescents with severe obesity, according to a report published Online First by JAMA Pediatrics, a JAMA Network publication.

5 Feb 2013

BD first quarter revenues increase 3.7% to $1.90 billion

BD, a leading global medical technology company, today reported quarterly revenues of $1.90 billion for the first fiscal quarter ended December 31, 2012, representing an increase of 3.7 percent from the prior-year period, or 5.2 percent on a foreign currency-neutral basis.

From BD (Becton, Dickinson and Company) 5 Feb 2013

MammaPrint breast cancer test can help women avoid chemotherapy

The MammaPrint breast cancer test can dramatically reduce the number of women who need to undergo chemotherapy to treat the disease, according to a newly published study.

5 Feb 2013

Insulin could increase risk of health complications in patients with type 2 diabetes

Patients with type 2 diabetes treated with insulin could be exposed to a greater risk of health complications including heart attack, stroke, cancer and eye complications a new study has found.

5 Feb 2013

Results from Merck’s Vorinostat phase 1 trial on lymphoma

Patients whose aggressive lymphomas have relapsed or failed to respond to the current front-line chemotherapy regimen now have an effective second line of attack against their disease.

5 Feb 2013

DCC receptor plays key role in regulating brain plasticity

Our ability to learn and form new memories is fully dependent on the brain's ability to be plastic - that is to change and adapt according to new experiences and environments. A new study from the Montreal Neurological Institute - The Neuro, McGill University, reveals that DCC, the receptor for a crucial protein in the nervous system known as netrin, plays a key role in regulating the plasticity of nerve cell connections in the brain.

5 Feb 2013

Risks and benefits of computed tomography in young adults

The underlying medical conditions facing young adults who undergo computed tomography (CT) exams represent a significantly greater health risk than that of radiation-induced cancer from CT, according to a new study published online in the journal Radiology.

5 Feb 2013

Orphan, St George's sign licensing agreement to develop new therapies for metabolic disorders

St George's, University of London has signed an exclusive worldwide licensing agreement with rare-disease research-and-development firm Orphan Technologies Ltd to develop new therapies for deadly metabolic disorders.

5 Feb 2013