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Androgens could constitute an efficient treatment against multiple sclerosis

Testosterone and its derivatives could constitute an efficient treatment against myelin diseases such as multiple sclerosis, reveals a study by researchers from the Laboratoire d'Imagerie et de Neurosciences Cognitives, in collaboration in particular with the "Neuroprotection et Neurorégénération: Molécules Neuroactives de Petite Taille" unit.

30 Jan 2013

IL-13 protein could be the key to development of fibrosis in Crohn's disease

New research has shown that a protein, known as IL-13, could be the key to the development of fibrosis in Crohn's disease. This breakthrough could help to advance new medicines to treat people suffering with the disease.

30 Jan 2013

No added benefit from perampanel in patients with epileptic fits

The drug perampanel has been approved since July 2012 as adjunctive therapy for adults and children aged 12 years and older with epileptic fits (seizures).

30 Jan 2013

MiR-182 deeply involved in memory formation within the amygdala brain structure

It takes a lot to make a memory. New proteins have to be synthesized, neuron structures altered. While some of these memory-building mechanisms are known, many are not. Some recent studies have indicated that a unique group of molecules called microRNAs, known to control production of proteins in cells, may play a far more important role in memory formation than previously thought.

30 Jan 2013

Keryx prices underwritten public offering of common stock

Keryx Biopharmaceuticals, Inc. today announced the pricing of its previously announced underwritten public offering of common stock consisting of 8,234,000 shares at $8.49 per share.

30 Jan 2013

Obama administration expected to continue science and technology diplomacy agenda, SciDev.Net reports

"The Obama administration is expected to continue including science and technology (S&T) in its diplomacy agenda, according to interviews with a number of people recognized for their contributions to international science cooperation," SciDev.Net reports.

30 Jan 2013

Microscopic hematuria poor indicator for renal, bladder malignancy

The presence of microscopic levels of blood in the urine is unreliable as an indicator for renal or bladder cancer, report researchers.

30 Jan 2013

ALDH1 expression predicts outcome in node-negative rectal cancer

Expression of the cancer stem cell marker aldehyde dehydrogenase 1 is an independent predictor for poor prognosis in node-negative rectal cancer, researchers say.

30 Jan 2013

Hospitalists flag patient overload threat to safety

Two-fifths of US hospitalists say their average patient load exceeds safe levels at least monthly, according to a nationwide survey.

30 Jan 2013

Birthweight extremes influence psychotic symptom severity

Both high and low birthweight increase the severity of psychotic symptoms, particularly disorganized and negative symptoms, research indicates.

30 Jan 2013

Bipolar pedigree endophenotypes found

Researchers have found cognitive endophenotypes in a single extended family showing linkage of bipolar disorder to a risk locus on chromosome 4.

30 Jan 2013

Maternal diet, first-year housing affect foals' osteochondrosis risk

Mares that are fed a diet that includes or is solely comprised of concentrates during gestation are significantly more likely to produce foals that develop permanent osteochondrosis lesions compared with mares who are fed a diet of roughage alone, report researchers.

30 Jan 2013