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FDA grants IDE approval to STS and ACC to study alternative access approaches for TAVR

The Society of Thoracic Surgeons (STS) and the American College of Cardiology (ACC) have received a unique investigational device exemption (IDE) from the U.S. Food and Drug Administration (FDA) to study "alternative access" approaches for transcatheter aortic valve replacement (TAVR) using the STS/ACC TVT Registry.

14 Feb 2013

Stress and mental illness: an interview with Professor Akira Sawa

As a psychiatrist I am interested in how stress may play a role in the pathology of adult mental disorders. You may know that most of the major mental illnesses, such as schizophrenia, mood-disorder, substance abuse or even anxiety disorder, become prominent in early adulthood.

14 Feb 2013

Cambodia, China report cases of avian influenza H5N1

"Cambodia reported on Wednesday that another four-year-old girl has contracted avian influenza H5N1, becoming the seventh person who infected the virus in 2013," Xinhua reports.

14 Feb 2013

Probiotics shows promise in reducing both incidence and severity of necrotizing enterocolitis

"Good" bacteria that live in our intestines have been linked with a variety of health benefits, from fighting disease to preventing obesity. In a new study, Kriston Ganguli of Massachusetts General Hospital for Children and Harvard Medical School and her colleagues have discovered another advantage to these friendly microscopic tenants: Chemicals secreted by good bacteria that typically live in the intestines of babies could reduce the frequency and severity of a common and often-lethal disease of premature infants.

14 Feb 2013

UNDP administrator calls for 'permanent' focus on NCDs

At the London launch of a Lancet series on non-communicable diseases (NCDs) on Monday, U.N. Development Programme Administrator Helen Clark said if NCDs are placed "permanently on the global development agenda, people's lives, opportunities, and future prospects will improve -- thereby advancing sustainable human development overall," Devex's "Development Newswire" blog reports.

14 Feb 2013

IQGAP1 molecule can suppress growth of tumors in the liver

A molecule already implicated in a number of diverse cellular functions can suppress the growth of tumors in the liver, a Mayo Clinic Cancer Center study has found. Its name is IQGAP1, and when the molecule is active in the cells that surround a tumor cell, this "tumor microenvironment" becomes less hospitable to cancer growth. When the molecule is deficient, cancer thrives.

14 Feb 2013

State roundup: Ore. considers rural doc loan repayment

Oregon would restore $4 million in the next biennium to fund a loan repayment program that assists primary health care providers willing to work in rural areas, under a bill being pushed by Sen. Elizabeth Steiner Hayward, D-Beaverton. The program ran for nearly two decades before it was cut in 2009 in the depths of the recession.

14 Feb 2013

Medgenics closes public offering of 5,600,000 shares of common stock and warrants

Medgenics, Inc., the developer of a novel platform technology for the sustained production and delivery of therapeutic proteins in patients using their own tissue, announces yesterday's closing of an underwritten public offering of 5,600,000 shares of common stock and Series 2013-A warrants to purchase up to an aggregate of 2,800,000 shares of common stock.

14 Feb 2013

Eleventh global case of SARS-linked virus confirmed in U.K.

"British officials say a mysterious virus related to SARS may have spread between humans, as they confirmed the 11th case worldwide of the new coronavirus in a patient who they say probably caught it from a family member," the Associated Press reports.

14 Feb 2013

Married people have better mental and physical health

Research shows that married people have better mental and physical health than their unmarried peers and are less likely to develop chronic conditions than their widowed or divorced counterparts.

14 Feb 2013

The Atlantic examines 'paradigm shift' in global health response

"The world has an 'historic opportunity' to contain and end three of humanity's deadliest scourges by focusing on their 'hot zones,' according to Mark Dybul, the newly appointed director of the Geneva-based Global Fund to Fight AIDS, Tuberculosis, and Malaria," the Atlantic reports in an article examining a "paradigm shift" in the global health response.

14 Feb 2013

FOXC2 vital to epithelial-mesenchymal transition in breast cancer

Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.

14 Feb 2013

College health plans beginning to accommodate transgender students

Over the last decade, as activists started pushing colleges to accommodate transgender students, they first raised only basic issues, like recognizing a name change or deciding who could use which bathrooms.

14 Feb 2013

IAP antagonists may actually increase risk of bone tumors

Cancer drugs should kill tumors, not encourage their spread. But new evidence suggests that an otherwise promising class of drugs may actually increase the risk of tumors spreading to bone, according to researchers at Washington University School of Medicine in St. Louis.

14 Feb 2013

State policies, positions on Medicaid expansion continue to take shape

North Carolina will not expand Medicaid coverage under President Barack Obama's signature health care reform law and will play no role in setting up the required health insurance exchange, Gov. Pat McCrory, a Republican, said on Tuesday.

14 Feb 2013

Researchers identify new way to influence the vital serotonin signaling system

An interdisciplinary team of researchers from the University of Texas Medical Branch at Galveston and the University of Houston has found a new way to influence the vital serotonin signaling system - possibly leading to more effective medications with fewer side effects.

14 Feb 2013

Study: No link between hospital readmissions and saving patient lives

A Journal of the American Medical Association study released Tuesday has found that higher hospital readmissions don't lead to fewer patient deaths.

14 Feb 2013

GSK1322322 targets gram-positive bacteria including methicillin-resistant strains of MRSA

An increasing number of bacteria is evolving antibiotic resistance. Much-feared representatives of this steadily growing group include Staphylococci strains. At this point, multi-resistant forms of the bacterium Staphylococcus aureus - the "hospital germ" known commonly by its acronym, MRSA - can only be treated with a select subset of antibiotics as many drugs have simply stopped working. This is precisely why the field of medicine is in desperate need of new treatment options.

14 Feb 2013

More polio workers killed than reported cases of disease, NPR reports

"The global effort to eradicate polio has reached a bizarre stage: More people have been gunned down recently over the disease than actually infected with it," NPR's "Shots" blog reports.

14 Feb 2013

Traumatic brain injury investigational treatment from BHR Pharma receives EMA orphan medicinal product designation

BHR Pharma, LLC announced today the European Medicines Agency (EMA), responsible for evaluating medicines developed for use in the European Union, granted an orphan medicinal product designation for treating moderate and severe traumatic brain injury (TBI) to its proprietary intravenous progesterone infusion agent, BHR-100. The agent currently is being evaluated as a neuroprotective treatment for severe traumatic brain injury (TBI) in the global, Phase III SyNAPSe® clinical trial.

14 Feb 2013